Reduced matrix rigidity promotes neonatal cardiomyocyte dedifferentiation, proliferation and clonal expansion [PDF]
eLife, 2015 Cardiomyocyte (CM) maturation in mammals is accompanied by a sharp decline in their proliferative and regenerative potential shortly after birth. In this study, we explored the role of the mechanical properties of the underlying matrix in the regulation ...
Yfat Yahalom-Ronen +4 more
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Linear Algebra and Its Applications, 2008 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
A Y Alfakih
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Data on the mechanobiological differences in the transcriptomes of human fetal and adult dermal fibroblasts in response to extracellular matrix rigidity [PDF]
Data in Brief, 2019 Fetal skin is known to proceed through the wound healing process without the formation of scar tissue but rather via regeneration. Fetal dermal fibroblasts have emerged as a significant driving force in this regenerative response due to their unique ...
Mitchell J. Leih +3 more
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Linear Algebra and Its Applications, 2000 Matrix rigidity has been introduced by \textit{L. G. Valiant} [Lect. Notes Comput. Sci. 53, 162-176 (1977; Zbl 0384.68046)] in connection with the complexity theory, namely that of proving nontrivial lower bounds on the length of computations. Valiant suggested that nonlinear lower bounds on the length of programs can be proved by constructing matrices
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Elucidating the Role of Matrix Porosity and Rigidity in Glioblastoma Type IV Progression
Applied Sciences, 2020 The highly infiltrating nature of glioma cells is the major cause for the poor prognosis of brain malignancies. Motility, proliferation, and gene expression of cells in natural and synthetic gels have been analyzed by several authors, yet quantitative ...
Rui C. Pereira +5 more
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Cardiomyocytes Sense Matrix Rigidity through a Combination of Muscle and Non-muscle Myosin Contractions [PDF]
Developmental Cell, 2018 Elisabeth Ehler +2 more
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Matrix rigidity differentially regulates invadopodia activity through ROCK1 and ROCK2 [PDF]
Biomaterials, 2016 Aron Parekh
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Zyxin Is Involved in Fibroblast Rigidity Sensing and Durotaxis
Frontiers in Cell and Developmental Biology, 2021 Focal adhesions (FAs) are specialized structures that enable cells to sense their extracellular matrix rigidity and transmit these signals to the interior of the cells, bringing about actin cytoskeleton reorganization, FA maturation, and cell migration ...
Ai Kia Yip +14 more
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Differential matrix rigidity response in breast cancer cell lines correlates with the tissue tropism. [PDF]
PLoS ONE, 2009 Metastasis to a variety of distant organs, such as lung, brain, bone, and liver, is a leading cause of mortality in the breast cancer patients. The tissue tropism of breast cancer metastasis has been recognized and studied extensively, but the cellular ...
Ana Kostic +2 more
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Probabilistic rank and matrix rigidity [PDF]
Proceedings of the 49th Annual ACM SIGACT Symposium on Theory of Computing, 2017 We consider a notion of probabilistic rank and probabilistic sign-rank of a matrix, which measures the extent to which a matrix can be probabilistically represented by low-rank matrices. We demonstrate several connections with matrix rigidity, communication complexity, and circuit lower bounds, including: The Walsh-Hadamard Transform is Not Very Rigid.
Josh Alman, R. Ryan Williams
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