Results 31 to 40 of about 56,763 (249)
Matrix rigidity regulates cancer cell growth and cellular phenotype.
PLoS ONE, 2010 BackgroundThe mechanical properties of the extracellular matrix have an important role in cell growth and differentiation. However, it is unclear as to what extent cancer cells respond to changes in the mechanical properties (rigidity/stiffness) of the ...
Robert W Tilghman +8 more
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Assessment of the Impact of the Rigidity of Nodes on the Operating Reliability of EPSs [PDF]
E3S Web of Conferences, 2019 The operating reliability of electrical power systems is mostly based on the topology and parameters of the schemes considered in this article. The preliminary (before the calculation of operating conditions) analysis of the rigidity or sensitivity of ...
Chemborisova Nailya
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Linking Matrix Rigidity with EMT and Cancer Invasion [PDF]
Developmental Cell, 2020 The extracellular matrix (ECM) plays a major role in cancer progression through its increased deposition and alignment. In this issue of Developmental Cell, Fattet et al. reveal a pathway in which ECM stiffness promotes EPHA2/LYN complex activation, leading to TWIST1 nuclear localization and triggering EMT in breast cancer.
Manon, Ros +2 more
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Data in Brief, 2022 Migration through the extracellular matrix (ECM) is essential for cancer cells to escape the primary tumor and invade neighboring tissues with the potential for metastasis [1].
Rachel Jerrell +2 more
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AUTEX Research Journal, 2021 Natural fiber-reinforced composites are getting more attention from researchers and manufacturing companies to replace metals and synthetic materials that have dominated the manufacturing industries.
Lemmi Tsegaye Sh. +2 more
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iScience, 2023 Summary: Contractile force generated in actomyosin stress fibers (SFs) is transmitted along SFs to the extracellular matrix (ECM), which contributes to cell migration and sensing of ECM rigidity.
Hiroki Katsuta +8 more
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Extracellular Matrix Rigidity Promotes Invadopodia Activity [PDF]
Current Biology, 2008 Invadopodia are actin-rich subcellular protrusions with associated proteases used by cancer cells to degrade extracellular matrix (ECM) [1]. Molecular components of invadopodia include branched actin-assembly proteins, membrane trafficking proteins, signaling proteins, and transmembrane proteinases [1]. Similar structures exist in nontransformed cells,
Alexander, Nelson R. +6 more
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Extracellular matrix rigidity modulates neuroblastoma cell differentiation and N-myc expression
Molecular Cancer, 2010 Neuroblastoma is a pediatric malignancy characterized by tremendous clinical heterogeneity, in which some tumors are extremely aggressive while others spontaneously differentiate into benign forms.
Umesh Vaibhavi +5 more
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Rigidity percolation in dispersions with a structured viscoelastic matrix [PDF]
Physical Review E, 2005 This paper deals with rigidity percolation in composite materials consisting of a dispersion of mineral particles in a microstructured viscoelastic matrix. The viscoelastic matrix in this specific case is a hydrocarbon refinery residue. In a set of model random composites the mean interparticle surface-to-surface distance was controlled, changing ...
Wilbrink, M.W.L. +3 more
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Matrix rigidity regulates cancer cell growth by modulating cellular metabolism and protein synthesis. [PDF]
PLoS ONE, 2012 Tumor cells in vivo encounter diverse types of microenvironments both at the site of the primary tumor and at sites of distant metastases. Understanding how the various mechanical properties of these microenvironments affect the biology of tumor cells ...
Robert W Tilghman +10 more
doaj +1 more source