Results 11 to 20 of about 33,810 (257)

A study on the influence of the dissolution test factors on in vitro release of ibuprofen from sustained release tablets [PDF]

open access: yesRomanian Journal of Pharmaceutical Practice, 2020
Objectives. The aim of this study was to investigate the influence of in vitro release test parameters on the release of ibuprofen from sustained release inert matrix tablets. Materials and methods.
Alexandra Pali   +4 more
doaj   +1 more source

Preparation and evaluation of sustained release carbamazepine matrix tablets using Eudragit RS 100 and Tragacanth [PDF]

open access: yesBulletin of Pharmaceutical Sciences. Assiut University, 2001
Carbamazepine is a widely prescribed anticonvulsant antiepileptic drug which shows variable absorption and variable bioavailability.  It is advisable to prep. it in sustained release dosage form to improve patient compliance and to perform const.
A. Aly, M. Ahmed
doaj   +1 more source

Evaluation of roll compaction as a preparation method for hydroxypropyl cellulose-based matrix tablets

open access: yesJournal of Pharmacy and Bioallied Sciences, 2011
Roll compaction was applied for the preparation of hydroxypropyl cellulose (HPC)-based sustained-release matrix tablets. Matrix tablets made via roll compaction exhibited higher dosage uniformity and faster drug release than direct-compacted tablets. HPC
Imjak Jeon, Tiziana Gilli, Gabriele Betz
doaj   +1 more source

Effect of Hydrophilic Polymers on the Release Rate and Pharmacokinetics of Acyclovir Tablets Obtained by Wet Granulation: In Vitro and In Vivo Assays

open access: yesMolecules, 2022
This study aims to evaluate the feasibility of producing acyclovir-containing modified release matrix tablets by a wet granulation method based on the type and concentration of two pharmaceutical-grade hydrophilic matrix polymers (i.e., hydroxypropyl ...
D. Nagasamy Venkatesh   +7 more
doaj   +1 more source

Modern polymers in matrix tablets technology

open access: yesPolymers in Medicine, 2014
Matrix tablets are the most popular method of oral drug administration, and polymeric materials have been used broadly in matrix formulations to modify and modulate drug release rate. The main goal of the system is to extend drug release profiles to maintain a constant in vivo plasma drug concentration and a consistent pharmacological effect. Polymeric
Łukasz, Zimmer   +2 more
openaire   +2 more sources

Design, Development and Evaluation of Matrix Tablet

open access: yesJournal of Biomedical and Pharmaceutical Research, 2021
Recently, sustained release formulations have become a very helpful tool in medical practice, providing patients with a variety of benefits. Sustained release is also a potential method for reducing pharmacological side effects by preventing fluctuations in the concentration of the drug in the plasma.
Arindam Chatterjee   +2 more
openaire   +2 more sources

Using of Sintering and Microwave Techniques to Control the Release of Trifluoperazine HCl fromWax Matrix

open access: yesAl-Mustansiriyah Journal of Pharmaceutical Sciences, 2010
The very water soluble drug, trifluoperazine HCl was prepared as sustained release carnauba wax matrix tablets using direct compression method. Different amounts of carnauba wax as matrix substance was used to show its effect on drug release.
Ahmed A. Hussein
doaj   +1 more source

A study on the influence of the formulation factors on in vitro release of ketoprofen from sustained release tablets [PDF]

open access: yesRomanian Journal of Pharmaceutical Practice, 2021
Objectives. The aim of this study was to investigate the influence of formulation factors on in vitro release of ketoprofen from sustained release inert matrix tablets. Materials and methods.
Larisa Cimpoaie   +2 more
doaj   +1 more source

New Hydrophilic Matrix Tablets for the Controlled Released of Chlorzoxazone. [PDF]

open access: yesInt J Mol Sci
The modified release of active substances such as chlorzoxazone from matrix tablets, based on Kollidon®SR and chitosan, depends both on the drug solubility in the dissolution medium and on the matrix composition. The aim of this study is to obtain some new oral matrix tablet formulations, based on Kollidon®SR and chitosan, in order to optimize the low ...
Creteanu A   +7 more
europepmc   +3 more sources

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