Results 21 to 30 of about 33,810 (257)
In order to achieve the therapeutic purpose, the choice of the most suitable delivery route is of indisputable importance. Therefore, certain factors must be taken into consideration when delivering a active substance, namely its own properties, the disease to be diagnosed and the desired beneficial time.
S. Parveen +5 more
openaire +2 more sources
Predicting the drug release kinetics of matrix tablets
In this paper we develop two mathematical models to predict the release kinetics of a water soluble drug from a polymer/excipient matrix tablet. The first of our models consists of a random walk on a weighted graph, where the vertices of the graph represent particles of drug, excipient and polymer, respectively. The graph itself is the contact graph of
Baeumer, Boris +5 more
openaire +3 more sources
Effect of polymers on in-vitro performance of eplerenone sustained release matrix tablets
Objectives: The intention of the present study was to design and assess oral sustained drug delivery systems for Eplerenone, using Cellulose and natural polymers as release modifiers in the form of matrix tablets.
Sunil Reddy +5 more
doaj +1 more source
A Review on Sustained Release Matrix Tablet
AbstractThe objective of the study was to explore the objectives, advantages and disadvantages ofsustained release matrix tablet. Different types of sustained release matrix tablet have beenexplained briefly along with various types of polymers that are used during the formulation.Various preparation methods are discussed here.
Rajesh Kuma, Vijay Sharma
openaire +2 more sources
Development and validation of a dissolution test for primaquine/polyethylene oxide matrix tablets
A simple, precise, specific, repeatable and discriminating dissolution test for primaquine (PQ) matrix tablets was developed and validated according to ICH and FDA guidelines. Two UV assaying methods were validated for determination of PQ released in 0.1
Ariane P. Cruz +6 more
doaj +3 more sources
The study was aimed at developing extended release matrix tablets of poorly water-soluble diclofenac sodium and highly water-soluble metformin hydrochloride by direct compression using cashew gum, xanthan gum and hydroxypropylmethylcellulose (HPMC) as ...
Kwabena Ofori-Kwakye +4 more
doaj +1 more source
Preparation and in-vitro evaluation of oral controlled-release matrix tablets containing diclofenac sodium [PDF]
Controlled-release matrix tablets contg. 100 mg-diclofenac sodium were successfully prepd. using egg albumin and three matrixes forming materials namely, sodium CM-cellulose (NaCMC), hydroxypropylmethyl cellulose (HPMC) and Eudragit RS.
F. Mohammed, M. Hassan, M. Fathy
doaj +1 more source
Formulation and Evaluation of Sustained Release Matrix Tablets of Aceclofenac
This study aimed to improve the dissolution rate of aceclofenac and release the drug in a controlled manner over a period of 24 hours. Matrix tablets were prepared by direct compression method, using hydrophilic polymers (HPMC/guar gum).
Priyanka Singh +3 more
doaj +1 more source
Formulation and evaluation of floating matrix tablet of stavudine
The purpose of the study was to prolong the gastric residence time of stavudine by designing its floating tablets and to study the influence of different polymers on its release rate.The floating mix matrix tablets of stavudine were prepared by melt granulation method. Beeswax was used as hydrophobic meltable material.
Prajapati, Pankaj H +2 more
openaire +3 more sources
DEVELOPMENT AND EVALUATION OF A PROLONGED-RELEASE MATRIX TABLETS OF DICLOFENAC SODIUM RESINATE [PDF]
The preparation of a potential prolonged-release matrix tablets (IER-tablets) containing diclofenac sodium – anion exchange resin (Dowex I-X8.Cl-) complexes has been performed by direct compression of the drug-resin complex (drug resinate) with various ...
Eman Samy, Ibrahim El-Gibaly
doaj +1 more source

