Results 21 to 30 of about 1,485,483 (289)

A Requirement for Fatty Acid Oxidation in the Hormone-Induced Meiotic Maturation of Mouse Oocytes [PDF]

open access: yes, 2013
We have previously shown that fatty acid oxidation (FAO) is required for AMP-activated protein kinase (PRKA)-induced maturation in vitro. In the present study, we have further investigated the role of this metabolic pathway in hormone-induced meiotic ...
Downs, Stephen, Valsangkar, Deepa
core   +2 more sources

Surface Functionalization of Silica Nanoparticles: Strategies to Optimize the Immune-Activating Profile of Carrier Platforms

open access: yesPharmaceutics, 2022
Silica nanoparticles (SiNPs) are generally regarded as safe and may represent an attractive carrier platform for nanomedical applications when loaded with biopharmaceuticals. Surface functionalization by different chemistries may help to optimize protein
Benjamin Punz   +6 more
doaj   +1 more source

Effects of endocrine-disrupting chemical exposure on zebrafish ovarian follicles [PDF]

open access: yes, 2017
The process of oocyte maturation involves both nuclear and cytoplasmic events that are essential for the production of viable eggs and subsequent fertilization in sexually reproducing animals.
D\u27Angelo, Josephine   +1 more
core   +2 more sources

Control of RelB during dendritic cell activation integrates canonical and noncanonical NF-κB pathways. [PDF]

open access: yes, 2012
The NF-κB protein RelB controls dendritic cell (DC) maturation and may be targeted therapeutically to manipulate T cell responses in disease. Here we report that RelB promoted DC activation not as the expected RelB-p52 effector of the noncanonical NF-κB ...
Asagiri, Masataka   +10 more
core   +2 more sources

An Overview of the Occurrence of Bioactive Peptides in Different Types of Cheeses

open access: yesFoods, 2023
The search for improvements in quality of life has increasingly involved changes in the diet, especially the consumption of foods which, in addition to having good nutritional value, are characterized by offering health benefits. Among the molecules that
Adriano Henrique do Nascimento Rangel   +9 more
doaj   +1 more source

Early maturation processes in coal. Part 1: Pyrolysis mass balances and structural evolution of coalified wood from the Morwell Brown Coal seam [PDF]

open access: yes, 2009
In this work, we develop a theoretical approach to evaluate maturation process of kerogen-like material, involving molecular dynamic reactive modeling with a reactive force field to simulate the thermal stress. The Morwell coal has been selected to study
Adler   +32 more
core   +3 more sources

Use of Specific Chemical Reagents for Detection of Modified Nucleotides in RNA

open access: yesJournal of Nucleic Acids, 2011
Naturally occurring cellular RNAs contain an impressive number of chemically distinct modified residues which appear posttranscriptionally, as a result of specific action of the corresponding RNA modification enzymes.
Isabelle Behm-Ansmant   +2 more
doaj   +1 more source

Towards a typology of continuative expressions

open access: yesLinguistic Typology at the Crossroads, 2023
This paper investigates the cross-linguistic diversity of continuative (‘still’) expressions. Based on a genealogically stratified sample of 120 languages, the continuative expressions are systematically analyzed according to the four following ...
Anastasia Panova
doaj   +1 more source

Exceptional increase in the creep life of magnesium rare-earth alloys due to localized bond stiffening

open access: yesNature Communications, 2017
Adding very small amounts of zinc to magnesium alloys containing rare earth elements dramatically improves their creep life. Here, the authors use first principles calculations and atomic-scale characterization to show that this is due to stiff covalent ...
Deep Choudhuri   +6 more
doaj   +1 more source

IL-27 Signaling Promotes Th1 Response by Downregulating IL-10 Production in DCs during Chlamydial Respiratory Infection

open access: yesMicroorganisms, 2023
Chlamydia trachomatis usually causes mucosal infections, bringing considerable morbidity and socioeconomic burden worldwide. We previously revealed that IL-27/IL-27R mediates protection against chlamydial invasion by promoting a protective Th1 response ...
Jiajia Zeng   +9 more
doaj   +1 more source

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