Results 41 to 50 of about 188,223,062 (256)

Pathophysiology of diabetes: An overview

Avicenna Journal of Medicine, 2020
Diabetes mellitus is a chronic heterogeneous metabolic disorder with complex pathogenesis. It is characterized by elevated blood glucose levels or hyperglycemia, which results from abnormalities in either insulin secretion or insulin action or both ...
Mujeeb Z Banday, Aga S Sameer, Saniya Nissar   +2 more
doaj   +1 more source

Neurologic Manifestations of Long COVID Affect Adult Females More Severely Than Males

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize differences in neurologic manifestations of postacute sequelae of SARS‐CoV‐2 infection (Neuro‐PASC) between females and males. Methods Cross‐sectional study of the first consecutive 261 posthospitalization Neuro‐PASC (PNP) and 2068 nonhospitalized Neuro‐PASC (NNP) patients evaluated at the Neuro‐COVID clinic between ...
Hannah Kopinsky, Melissa Lopez, Janet Miller, Millenia Jimenez, Eric M. Liotta, Igor J. Koralnik   +5 more
wiley   +1 more source

Treatment implications of a delayed diagnosis of maturity-onset diabetes of the young

, 2021
Maturity-onset diabetes of the young (MODY) is a rare form of monogeneic diabetes that classically presents as non-insulin requiring diabetes with evidence of autosomal dominant inheritance in individuals who are typically young and lean.
Brown, F, Ekinci, EI, Ali, AS
core   +1 more source

Changes in Immune‐Inflammation Status and Prognosis in Pregnancy‐Related Cerebral Venous Thrombosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Distinguishing pathological changes from physiological adaptations in pregnancy‐related cerebral venous thrombosis (CVT) is clinically challenging. This study aimed to characterize coagulation, immune‐inflammation, and dehydration status in these patients and assess their prognostic value.
Xiaoming Zhang, Zilin Xu, Ran Duan, Chunxiao Lu, Da Zhou, Chen Zhou, Ran Meng, Xunming Ji   +7 more
wiley   +1 more source

Case Report: A Novel ABCC8 Variant in a Chinese Pedigree of Maturity-Onset Diabetes of the Young

Frontiers in Endocrinology, 2021
BackgroundWe aimed to analyze a novel ABCC8 variant of a Chinese patient with suspected maturity-onset diabetes of the young (MODY) and to provide evidence for precise diagnosis and appropriate treatment.MethodA Chinese family with suspected MODY was ...
Chaoyan Tang, Liheng Meng, Ping Zhang, Xinghuan Liang, Chaozhi Dang, Hui Liang, Junfeng Wu, Haiyun Lan, Yingfen Qin   +8 more
doaj   +1 more source

Incident Comorbid Diabetes and Outcomes in Multiple Sclerosis: An English Population‐Based Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To compare the incidence of diabetes mellitus and its associations with hospitalisation and mortality in adults with multiple sclerosis (MS) and matched controls. Methods Using English primary care data from the Clinical Practice Research Datalink, linked to hospital and mortality records, we matched adults with MS with up to 10 ...
Yolanda Lau, Sedigheh Zabihi, Morghan Hartmann, Georgina Mathlin, Sube Banerjee, Ebaa Marouf, Clare Hadley, Claudia Cooper, Ruth Dobson   +8 more
wiley   +1 more source

Primary pancreatic lymphoma in a patient with maturity onset diabetes of the young type 3 [PDF]

, 2012
Primary pancreatic lymphoma (PPL) is an extremely rare disease which occurs in pancreas, accounts for less than 1% of extra-nodal malignant lymphomas and 0,5% of cases of pancreatic masses.
Hohaus, Stefan, Calcagni, Maria Lucia, Pitocco, Dario, Teofili, Luciana, Luigi Pianese, Alberto Larghi, Larghi, Alberto, Stefano Tumini, Larocca, Luigi Maria, D'Alo', Francesco, Valentina Bozzoli, Luciana Teofili, Maria Lucia Calcagni, Dario Pitocco, Rufini, Vittoria, Bozzoli, Valentina, Giuseppina Massini, Vittoria Rufini, Francesco D'Alò, Luigi Maria Larocca, Stefan Hohaus, Massini, Giuseppina, Maria Chiara Tisi   +22 more
core   +1 more source

Rheumatoid Arthritis and Coronary Artery Calcium Progression: A Case Cohort Analysis From ELSA‐Brasil

Arthritis Care &Research, EarlyView.
Objective To investigate the association between rheumatoid arthritis (RA) and coronary artery calcium (CAC) prevalence, incidence, and progression over four years in adults without prior cardiovascular disease. Methods A case‐cohort study within the Brazilian Longitudinal Study of Adult Health (ELSA‐Brasil) included 585 participants (86 patients with ...
Patrícia Fonseca Estrada, Marcos Rafael N. Cavalcante, Itamar de Souza Santos, Márcio S. Bittencourt, Vandrize Meneghini, Paulo A. Lotufo, Alessandra C. Goulart, Isabela M. Bensenor   +7 more
wiley   +1 more source

Incidence, Risk Factors and Management of Adverse Events in Contemporary Real‐World Care of Children with Juvenile Idiopathic Arthritis

Arthritis Care &Research, Accepted Article.
Objective We describe the frequency, risk factors, severity, and management of actionable and serious adverse events (AAE and SAE) in children with newly diagnosed Juvenile Idiopathic Arthritis (JIA) in Canada. Methods We enrolled patients within 3 months of JIA diagnosis in the Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) Registry,
Bashayer Alnuaimi, Roberta A. Berard, Jean‐Philippe Proulx‐Gauthier, Heinrike Schmeling, Michelle Batthish, Gilles Boire, Adam M. Huber, Dax G. Rumsey, Jaime Guzman, Gaëlle Chédeville, The CAPRI registry Investigators   +10 more
wiley   +1 more source

A genome-wide scan in families with maturity-onset diabetes of the young: evidence for further genetic heterogeneity.

, 2003
Maturity-onset diabetes of the young (MODY) is a heterogeneous single gene disorder characterized by non-insulin-dependent diabetes, an early onset and autosomal dominant inheritance. Mutations in six genes have been shown to cause MODY. Approximately 15-
Benmezroua, Y, Rao, PS, Lindgren, Cecilia,, Lindgren, Cecilia M, Menzel, Stephan, Rao, Pamidghantam Subba, Almgren, Peter,, Groop, Leif,, Pedersen, Oluf, Cognet, I, Chevre, Jean Claude, Almgren, Peter, Almgren, P, Cognet, Ignacio, Tuomi, Tiinamaija,, Wright-Pascoe, Rosemarie, Wright-Pascoe, R, Wang, Youxiang, Bulman, MP, Menzel, S, Tuomi, T, Hattersley, Andrew T., Mills, J, Wishart, M, Vaxillaire, Martine, Evans, Julie C, Hattersley, Andrew T, Kanninen, Timo, Mills, James, Prisco, Francesco, Hansen, Torben, Evans, JC, Costa, A, Dina, Christian, Dina, C, Lund University., Mahtani, Melanie M., Ellard, Sian, Froguel, Philippe, Vaxillaire, M, Hansen, T, Brown, A, Lindgren, Cecilia, Pedersen, O, Bulman, Michael P., Lecoeur, Cécile, Frayling, Timothy M., Costa, Angels, Benmezroua, Yamina, Prisco, F, Groop, Leif C, Wang, Y, Evans, Julie C., Lecoeur, C, Bulman, Michael P, Groop, Leif, Wishart, Marie, Mahtani, MM, Chevre, JC, Frayling, Timothy M, Mahtani, Melanie M, Ellard, S, Frayling, TM, Kanninen, T, Froguel, P, Brown, Alison, Tuomi, Tiinamaija, Frayling, T M, Hattersley, A T, Groop, L C, Conget, I, Chevre, J C, Lindgren, C M, Bulman, M P, Kaninen, T, Toumi, T, Subba Rao, P V, Evans, J C, Menzel, S; id_orcid, Mahtani, M M   +79 more
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