Results 141 to 150 of about 177,423,405 (278)

Genetic Biomarkers in the Risk Assessment of Sudden Cardiac Events: A Personalized Approach

iNew Medicine, EarlyView.
Genetic insights into the risk assessment of sudden cardiac events. ABSTRACT Sudden cardiac events are the leading cause of death worldwide. Conventional risk stratification methods, which largely depend on clinical history, imaging, and electrocardiography, are usually inadequate for identifying high‐risk individuals, especially those without visible ...
Shrikant Verma, Sushma Verma, Mohammad Abbas, Tabrez Faruqui, Bashir Ahmad Mir, Farzana Mahdi   +5 more
wiley   +1 more source

Phenotypic heterogeneity and polygenic risk scores in a family of maturity-onset diabetes of the young. [PDF]

JCEM Case Rep
Chatchomchuan W, Thewjitcharoen Y, Nakasatien S, Himathongkam T, Lim CKP, Chan JCN.   +5 more
europepmc   +1 more source

High‐Sugar Diet and Intestinal Diseases: A Shared Microbiota–Barrier–Immunity–Metabolism Axis in Inflammatory Bowel Disease, Food Allergy, and Colorectal Cancer

iNew Medicine, EarlyView.
ABSTRACT The global incidence of intestinal diseases—including food allergy, inflammatory bowel disease (IBD), and colorectal cancer (CRC)—continues to escalate in parallel with the expansion of the “Western diet,” within which the high‐sugar diet (HSD) has emerged as a pivotal yet under‐recognized dietary driver.
Yuchen Wang, Yajuan Wu, Huayang Sheng, Shouhong Jiang, Jinping Cheng, Ye Kuang, Miao Liu, Lei Feng, Yanan Sun, Jinzhi Duan   +9 more
wiley   +1 more source

Identification and functional characterization of a novel mutation in the NEUROD1 gene in a Chinese family with maturity-onset diabetes of the young. [PDF]

Acta Diabetol
Li J, Zhang J, Ren S, Liu Y, Wu C, Dong J, Zhu C, Chen S, Zhang H, Li T, Jiang Y.   +10 more
europepmc   +1 more source

The role of rare copy number variants in early‐onset depression

JCPP Advances, EarlyView.
Abstract Background Depression is a highly heterogeneous condition. Depression with an onset in childhood and early adolescence has a worse clinical course, is more heritable, and shows a lower genetic correlation with other depression subtypes, than does later‐onset depression.
Charlotte A. Dennison, Ida Sønderby, Miguel Garcia‐Argibay, Victoria Powell, Amy Shakeshaft, Lucy Riglin, Elliott Rees, Michael O’Donovan, Henrik Larsson, Ole Andreassen, Alexandra Havdahl, Joanna Martin, Anita Thapar   +12 more
wiley   +1 more source

Treatment Options for Patients with Maturity-Onset Diabetes of the Young (MODY): A Systematic Review of Literature: 2026 Update. [PDF]

Diabetes Ther
Zagaroli L, Di Berardino A, Petragnano F, Lustri S, Fasciani I, Rossi M, Baroni MG, Delvecchio M.   +7 more
europepmc   +1 more source

Nutritional and environmental determinants of maturation and disruption of the early life gut microbiome: A narrative review

Journal of Parenteral and Enteral Nutrition, EarlyView.
Abstract The first 1000 days of life represent a critical window for gut microbiome assembly, with lifelong implications for child growth, immune development, and disease risk. This review synthesizes evidence on maternal, perinatal, and especially nutritional factors that influence early‐life intestinal colonization and highlights the consequences of ...
Carly Burow, Romy Shenderey, Fariha Chowdhury, Nyah Shah, Nikhil Pai   +4 more
wiley   +1 more source

HNF1A-Maturity-Onset Diabetes of the Young (MODY) in a Family With a Rare Silent Variant: Clinical Challenges and Variable Expressivity. [PDF]

Cureus
Carvalho R, Moreira B, Parente S.
europepmc   +1 more source

Patient regret in tooth extraction for periodontitis: Highlighting the role of patient involvement in decision‐making

Journal of Periodontology, EarlyView.
Abstract Background Tooth extraction is one of the most common irreversible treatment options in dentistry, and it may lead to complex emotional responses such as patient regret. This study aimed to assess the extent of decisional regret among patients who underwent tooth extraction due to periodontal disease and to identify associated influencing ...
Kyung‐A Ko, Ji‐Young Jung, Youngkyung Ko, Nicolas P. A. Müller, Junhewk Kim, Jung‐Seok Lee   +5 more
wiley   +1 more source

Genomic landscape of Mexican patients with maturity onset diabetes of the young: beyond mutations in MODY-known genes. [PDF]

Front Endocrinol (Lausanne)
Moscona-Nissan A, Marrero-Rodríguez D, Andonegui-Elguera S, Luna-Ávila ES, Martínez-Mendoza F, Vela-Patiño S, Ramírez-Ramos I, Hinojosa-Alvarez S, Hernandez-Perez J, Chavez-Santoscoy RA, Mercado-Medrez S, León-Wu KS, De Miguel-Ibáñez R, Mercado M, Taniguchi-Ponciano K, Ferreira-Hermosillo A.   +15 more
europepmc   +1 more source