Antimicrobial peptides: agents of border protection for companion animals. [PDF]
Over the past 20 years, there have been significant inroads into understanding the roles of antimicrobial peptides in homeostatic functions and their involvement in disease pathogenesis.
Affolter, Verena K +2 more
core +1 more source
Melanocortin 1 Receptor (MC1R): Pharmacological and Therapeutic Aspects
Melanocortins play crucial roles in regulating the stress response, inflammation, and skin pigmentation. In this review, we focus on the melanocortin 1 receptor (MC1R), a G protein-coupled receptor primarily known for regulating skin pigmentation and exhibiting anti-inflammatory effects.
Mun, Yoonwoo +2 more
openaire +2 more sources
Polymorphic loci of coat color in mini-pigs
The present work is phenomenological and purely descriptive. It shows polymorphism of colors in a breeding group of mini-pig in the Institute of Cytology and Genetics of the Siberian Branch of the Russian Academy of Sciences (ICG SB RAS) and makes some ...
S. V. Nikitin +5 more
doaj +1 more source
Use of domesticated pigs by Mesolithic hunter-gatherers in northwestern Europe [PDF]
Acknowledgements We thank the Archaeological State Museum Schleswig-Holstein, the Archaeological State Offices of Brandenburg, Lower Saxony and Saxony and the following individuals who provided sample material: Betty Arndt, Jo¨rg Ewersen, Frederick ...
A Cooper +33 more
core +1 more source
Discriminant analysis of colour measurements reveals allele dosage effect of ASIP/MC1R in bay horses
Considering the variability of bay coat colour, we aimed to investigate the association of different shades of bay with ASIP and MC1R genotype combinations and we studied the discrimination between the bay and black coat colour.
Thomas Druml +3 more
doaj +1 more source
Spotlight on islands.On the origin and diversification of an ancient lineage of the Italian wall lizard Podarcis siculus in the western Pontine Islands [PDF]
Groups of proximate continental islands may conceal more tangled phylogeographic patterns than oceanic archipelagos as a consequence of repeated sea level changes, which allow populations to experience gene flow during periods of low sea level stands and
Castiglia, Riccardo +6 more
core +3 more sources
Pig Coat Color Manipulation by MC1R Gene Editing
Black coat color in pigs is determined by the dominant E allele at the MC1R locus. Through comparing MC1R gene sequences between recessive e and dominant ED1 alleles, we identified four missense mutations that could affect MC1R protein function for eumelanin synthesis.
Haiwen Zhong +7 more
openaire +2 more sources
A simple DNA based method for determination of pure Black Slavonian pigs
The aim of this work was to determine the MC1R genotype of Black Slavonian pigs and to find an efficient and simple PCR-RFLP method, based on differences in MC1R genotype, to distinguish between purebred Black Slavonian pigs and their crossings with ...
Polona Margeta +4 more
doaj +1 more source
Evolutionary and demographic correlates of Pleistocene coastline changes in the Sicilian wall lizard Podarcis wagleriana [PDF]
Aim Emergence of coastal lowlands during Pleistocene ice ages might have provided conditions for glacial expansions (demographic and spatial), rather than contraction, of coastal populations of temperate species. Here, we tested these predictions in the
Canestrelli, Daniele +6 more
core +1 more source
MC1R Variants Increase Risk of Melanomas Harboring BRAF Mutations [PDF]
Melanocortin-1 receptor (MC1R) variants have been associated with BRAF (v-raf murine sarcoma viral oncogene homolog B1) mutations in non-CSD (chronic solar-damaged) melanomas in an Italian and an American population. We studied an independent Italian population of 330 subjects (165 melanoma patients and 165 controls) to verify and estimate the ...
Fargnoli, Mc +16 more
openaire +7 more sources

