Results 21 to 30 of about 9,263 (182)

Molecular Marker-Assisted Selection of Green Shank and White Feather Traits in Chickens

Guangdong nongye kexue, 2023
【Objective】The shank and feather color, as the characteristic traits of breeds, which remains an important selective trait in the breeding process of new varieties.
Xuewen CHAI, Jishang GONG, Fangfang CUI, Zhaofeng KANG, Yanping WU, Min ZHOU, Xuemei SUN, Jiguo XU   +7 more
doaj   +1 more source

Coat Color of Korean Brindle Cattle and Melanocortin 1 Receptor (MC1R) mRNA: Variation of 3'-Untranslated Region and Expression

Journal of Animal Reproduction and Biotechnology, 2014
The objective of this study was to determine the breed differences in the 3'-untranslated region (UTR) of MC1R mRNA, which may be used to distinguish Korean brindle cattle (Chikso) from other breeds. We investigated the relationship between the variation
Hae-Lee Lee, Jae-Hee Park, Jong Gug Kim
doaj   +1 more source

The protective role of MC1R in chromosome stability and centromeric integrity in melanocytes

Cell Death Discovery, 2021
Variants in the melanocortin-1 receptor (MC1R) gene, encoding a trimeric G-protein-coupled receptor and activated by α-melanocyte-stimulating hormone (α-MSH), are frequently associated with red or blonde hair, fair skin, freckling, and skin sensitivity ...
Xin Li, Weiwei Mao, Jie Chen, Colin R. Goding, Rutao Cui, Zhi-Xiang Xu, Xiao Miao   +6 more
doaj   +1 more source

A simple DNA based method for determination of pure Black Slavonian pigs

Italian Journal of Animal Science, 2010
The aim of this work was to determine the MC1R genotype of Black Slavonian pigs and to find an efficient and simple PCR-RFLP method, based on differences in MC1R genotype, to distinguish between purebred Black Slavonian pigs and their crossings with ...
Polona Margeta, Damir Jakšić, Peter Dovč, Gordana Kralik, Vladimir Margeta   +4 more
doaj   +1 more source

Functional Characterization of MC1R-TUBB3 Intergenic Splice Variants of the Human Melanocortin 1 Receptor.

PLoS ONE, 2015
The melanocortin 1 receptor gene (MC1R) expressed in melanocytes is a major determinant of skin pigmentation. It encodes a Gs protein-coupled receptor activated by α-melanocyte stimulating hormone (αMSH).
Cecilia Herraiz, Conchi Olivares, Maria Castejón-Griñán, Marta Abrisqueta, Celia Jiménez-Cervantes, José Carlos García-Borrón   +5 more
doaj   +1 more source

MC1RVariation in a New Mexico Population [PDF]

Cancer Epidemiology, Biomarkers & Prevention, 2019
AbstractBackground:The Melanocortin 1 Receptor (MC1R) contributes to pigmentation, an important risk factor for developing melanoma. Evaluating SNPs in MC1R and association with race/ethnicity, skin type, and perceived cancer risk in a New Mexico (NM) population will elucidate the role of MC1R in a multicultural population.Methods:We genotyped MC1R in ...
Kirsten A.M. White, Yvonne T. Dailey, Dolores D. Guest, Kate Zielaskowski, Erika Robers, Andrew Sussman, Keith Hunley, Christopher R. Hughes, Matthew R. Schwartz, Kimberly A. Kaphingst, David B. Buller, Jennifer L. Hay, Marianne Berwick   +12 more
openaire   +2 more sources

The MC1R gene in the guppy (Poecilia reticulata): Genotypic and phenotypic polymorphisms

BMC Research Notes, 2011
Background The guppy (Poecilia reticulata) is an important model organism for studying sexual selection; male guppies have complex and conspicuous pigmentation, and female guppies exhibit preferences for males with specific color spots. Understanding the
Yokoyama Jun, Yamamoto Hiroaki, Tezuka Ayumi, van Oosterhout Cock, Kawata Masakado   +4 more
doaj   +1 more source

Gene Expression Regulation by Agonist-Independent Constitutive Signaling of Melanocortin-1 Receptor [PDF]

Endocrinology and Metabolism, 2014
BackgroundMelanocortin-1 receptor (Mc1r), a key signaling receptor for melanogenesis, has been reported to mediate migration of B16F10 melanoma cells.
Ikjoo Seong, Jaesang Kim
doaj   +1 more source

Functional divergence of the pigmentation gene melanocortin-1 receptor (MC1R) in six endemic Macaca species on Sulawesi Island

Scientific Reports, 2022
Coat color is often highly variable within and between animal taxa. Among hundreds of pigmentation-related genes, melanocortin-1 receptor (MC1R) plays key roles in regulating the synthesis of the dark eumelanin and the red–yellow pheomelanin.
Xiaochan Yan, Yohey Terai, Kanthi Arum Widayati, Akihiro Itoigawa, Laurentia Henrieta Permita Sari Purba, Fahri Fahri, Bambang Suryobroto, Hiroo Imai   +7 more
doaj   +1 more source

Targeting MC1R depalmitoylation to prevent melanomagenesis in redheads [PDF]

Nature Communications, 2019
AbstractSome genetic melanocortin-1 receptor (MC1R) variants responsible for human red hair color (RHC-variants) are consequently associated with increased melanoma risk. Although MC1R signaling is critically dependent on its palmitoylation primarily mediated by the ZDHHC13 protein-acyl transferase, whether increasing MC1R palmitoylation represents a ...
Shuyang Chen, Changpeng Han, Xiao Miao, Xin Li, Chengqian Yin, Junrong Zou, Min Liu, Shanshan Li, Lukasz Stawski, Bo Zhu, Qiong Shi, Zhi-Xiang Xu, Chunying Li, Colin R. Goding, Jun Zhou, Rutao Cui   +15 more
openaire   +4 more sources