Results 41 to 50 of about 11,568 (220)

Heterodimerization of MC1R and MC1R-TUBB3 chimeric isoforms.

, 2015
(A) Co-immunoprecipitation of MC1R-001 and the MC1R-TUBB3 chimeric isoforms. HEK293T cells expressing the indicated constructs were lysed and immunoprecipitated for Flag-labelled MC1R-001, Iso1 or Iso2 using an anti-Flag monoclonal antibody.
Celia Jiménez-Cervantes (836701), José Carlos García-Borrón (836702), Marta Abrisqueta (836700), Cecilia Herraiz (836697), Maria Castejón-Griñán (836699), Conchi Olivares (836698)   +5 more
core   +1 more source

Two MC1R loss-of-function alleles in cream-coloured Australian Cattle Dogs and white Huskies. [PDF]

, 2018
Loss-of-function variants in the MC1R gene cause recessive red or yellow coat-colour phenotypes in many species. The canine MC1R:c.916C>T (p.Arg306Ter) variant is widespread and found in a homozygous state in many uniformly yellow- or red-coloured dogs ...
Hadji Rasouliha, Sheida, Hytönen, M K, Loechel, R, Mauri, Nico, Dietrich, Sara Joëlle, Schmutz, S M, Wiedmer, Michaela, Kehl, A, Jagannathan, Vidhya, Leeb, Tosso, Letko, Anna, Dürig, Nicole, Lohi, H, Drögemüller, Michaela, Lepori, Vincent   +14 more
core   +1 more source

MC1R protein expression.

, 2014
Western blotting was performed in order to detect MC1R protein expression in mouse and human tissue. Left panel: incubation with a rabbit polyclonal MC1R antibody (Alomone Labs).
Martin E. Johansson (119842), Börje Haraldsson (5653147), Annika Lindskog Jonsson (517299), Jenny Nyström (353585), Johannes Elvin (517300), Anna Granqvist (353582)   +5 more
core   +1 more source

CDKN2A and MC1R analysis in amelanotic and pigmented melanoma

Melanoma Research, 2009
Amelanotic melanoma (AM) is a rare subtype of melanoma with little or no clinically visible pigment; it is more difficult to diagnose than pigmented melanoma (PM), and has a worse prognosis. In the attempt to find a genetic explanation for the distinction between AM and PM, we conducted a case-case study, matching AM and PM patients, and testing them ...
GHIORZO, PAOLA, PASTORINO, LORENZA, Pizzichetta MA, Bono R, Queirolo P, Talamini R, Annessi G, BRUNO, WILLIAM, NASTI, SABINA, GARGIULO, SARA, BATTISTUZZI, LINDA, Sini MC, Palmieri G, BIANCHI, GIOVANNA, Italian Melanoma Intergroup   +14 more
openaire   +6 more sources

Bioinformatics Analysis of the Melanocortin 1 Receptor Gene (MC1R) in the Southern Platyfish Xiphophorus maculatus (Günther, 1866) [PDF]

International Journal Bioautomation, 2020
The Southern platyfish Xiphophorus maculatus is one of the most popular ornamental fish used widely as a premier model system in understanding the genetic basis of color pattern polymorphism. Coloration in X.
Abdul Khader Sultan Mohideen, Anbu Arun
doaj   +1 more source

Alpha‐Synuclein Promotes Anterograde Vesicle Transport in Melanocytes and Melanoma Cells: A Pro‐Survival Function

Journal of the Chinese Chemical Society, EarlyView.
Model for how α‐syn modulates the positioning of endolysosomes in melanoma cells. (a) α‐syn tethers endolysosomes to the plasma membrane, a last step in anterograde transport. (b) Loss of α‐syn expression causes the loss of the tethering function, which leads to perinuclear vesicle clustering. Reproduced from the open access article.
Stephan N. Witt
wiley   +1 more source

MC1R Alligment

, 2015
MC1R ...
Wakamatsu, Kazumasa, Luis M. San-José (3319257), Béziers, Paul, Paul Béziers (3261750), Alexandre Roulin (482076), Simon, Céline, Roulin, Alexandre, Anne-Lyse Ducrest (3191806), San-José, Luis M., Ducrest, Anne-Lyse, Ducret, Valérie, Valérie Ducret (3194052), Céline Simon (482074), Kazumasa Wakamatsu (55669)   +13 more
core   +1 more source

Towards the identity of different Crna slavonska pig breed gene pools [PDF]

Journal of Central European Agriculture, 2018
The microsatellite (MS) genetic diversity studies on CS pig breed showed subclustering of this breed. Structuring results based on MS data of 70 CS pigs were compared to the MC1R coat color gene genotyping results.
Polonca Margeta, Kristina Gvozdanović, Krešimir Salajpal, Goran Kušec   +3 more
doaj   +1 more source

Association of MC1R variation and plumage color diversity of Nigerian domestic pigeon (Columba livia domestica)

Journal of Advanced Veterinary and Animal Research, 2022
Objectives: Domestic pigeons (Columba livia domestica) have diverse plumage pigmentations. Melanocortin 1 receptor (MC1R) gene variation has been correlated with color traits.
Xiang-Xiang Jiang, Adeniyi Charles Adeola, Foluke Eunice Sola-Ojo, Ibraheem Atolagbe Abubakar, Isiaka Hannah Fatima, Ojuerayetan Judah Olaoluwa, Abdulwahab Barakat Abodurin, Olawale Abdulafeez Olasunkanmi, Oladejo Hafsat Abisola, Oladipo Uthman, Adeshina Esther Kehinde, Hussein Hamidat, Taiwo Eyitayo Nishola, Semiu Folaniyi Bello, Min-Sheng Peng, Ya-Ping Zhang   +15 more
doaj   +1 more source

Cutaneous Pigmentary Changes During Setmelanotide Therapy: Dermoscopic and Confocal Findings in Two Patients

JEADV Clinical Practice, EarlyView.
ABSTRACT Setmelanotide is a melanocortin‐4 receptor agonist approved for the treatment of rare forms of genetic obesity. Through off‐target activation of the melanocortin‐1 receptor, it may induce cutaneous pigmentation changes; however, data regarding its effects on melanocytic nevi remain limited.
Martina Cavicchi, Claudia Lasagni, Silvana Ciardo, Francesca Giusti, Albino Eccher, Caterina Longo   +5 more
wiley   +1 more source