Results 91 to 100 of about 3,352 (198)
Skin microbiome engineering: Challenges and opportunities in skin diseases treatment
iMetaOmics, Volume 2, Issue 2, June 2025.The skin microbiome plays a crucial role in skin health, influencing barrier integrity, immune responses, and disease susceptibility. Various interventions can reshape the microbiome, broadly categorized into targeted and untargeted approaches. Targeted strategies, such as phage therapy, engineered bacteria, and phage lysins, selectively modulate ...
Yiang Lyu, Juntao Shen, You Che, Lei Dai
wiley +1 more source
Experimental Dermatology, Volume 34, Issue 3, March 2025.ABSTRACT This meta‐analysis presents findings from nine studies involving 4626 cases of primary Merkel cell carcinoma (MCC), aimed at evaluating the relationship between primary MCC and the incidence of a second skin cancer. The analysis reveals a significant association, with a calculated risk ratio of 2.97 (95% CI, 1.70–5.19, p = 0.0001), indicating ...
Trairong Chokwassanasakulkit +1 more
wiley +1 more source
Presence of Merkel cell polyomavirus DNA and large-T antigen in keratinocyte carcinomas and its correlation with immunohistochemical markers p16, p53 and ki67 [PDF]
Anais Brasileiros de DermatologiaBackground Merkel cell polyomavirus (MCPyV), a human polyomavirus that is unequivocally linked to merkel cell carcinoma (MCC), has been found in association with keratinocytes carcinomas (KC), especially basal cell carcinoma (BCC) and cutaneous squamous ...
T.R. Bellott +6 more
doaj +1 more source
The Role of Viruses in Cellular Transformation and Cancer
Cancer Reports, Volume 8, Issue 2, February 2025.ABSTRACT Background Viral infections are established contributors to oncogenesis, leading to significant public health challenges. This systematic review aims to synthesize current knowledge on the mechanisms of viral cellular transformation and their association with various cancers.
Donath Damian
wiley +1 more source
Multiple DNA Viruses and HPV Integration in Inverted Papilloma and Associated Sinonasal Carcinoma
The Laryngoscope, Volume 135, Issue 2, Page 677-686, February 2025.HPV6 integration was observed in benign inverted papilloma, whereas HPV16 is present pre‐ and post‐malignant transformation. Marked increase in viral diversity was present, supported by accumulation of mutations over time. Objectives Sinonasal inverted papilloma (IP) has a locally destructive growth pattern, can relapse, and can undergo malignant ...
Maria K. Jauhiainen +9 more
wiley +1 more source
healthbook TIMES. Oncology Hematology, 2019 Merkel cell carcinoma (MCC) is a rare and difficult-to-treat cutaneous malignancy with a poor prognosis. Treatment protocols for localized MCC are well established.
Deborah Zihler +2 more
doaj +1 more source
Cancer Medicine, Volume 14, Issue 1, January 2025.ABSTRACT Objective The lack of consensus on the benefits and harms of standard therapies, including surgery (SRx), radiotherapy (RTx), chemotherapy (CTx), and their combinations among early‐stage MCC, prompted this study. Methods A systematic review and meta‐analysis of randomized and non‐randomized studies published between January 01, 1972, and ...
Yves Paul Vincent Mbous +7 more
wiley +1 more source
Depicting CREB-Dependent Transcriptome in MCPyV+ and MCPyV- Merkel Cell Carcinoma Cells
, 2021 Merkel Cell Carcinoma (MCC) is a highly malignant neuroendocrine tumor with an increasing incidence and the highest mortality rate amongst skin cancers (30%). They are usually diagnosed at advanced stages and still lack precise markers for diagnosis. MCC has two main etiologies: polyomavirus-positive (MCPyV+) and -negative (MCPyV-).
openaire +1 more source
Merkel Cell Polyomavirus DNA in Persons without Merkel Cell Carcinoma
Emerging Infectious Diseases, 2009 Merkel cell polyomavirus (MCPyV) DNA was detected in 88% of Merkel cell carcinomas in contrast to 16% of other skin tumors. MCPyV was also found in anogenital and oral samples (31%) and eyebrow hairs (50%) of HIV-positive men and in forehead swabs (62 ...
Ulrike Wieland +4 more
doaj +1 more source
Human papillomavirus (HPV) and Merkel cell polyomavirus (MCPyV) in non small cell lung cancer
Experimental and Molecular Pathology, 2010 Certain types of human papillomavirus (HPV) induce cancers, especially cervical cancers in women. A meta-analysis of the literature suggests that HPV is also associated with 20%-25% of non small cell lung carcinoma (NSCLC). Merkel cell Polyomavirus (MCPyV) causes most Merkel cell carcinomas in immunocompromised hosts, and is associated with some ...
Joongho, Joh +6 more
openaire +2 more sources