Clinicopathological features,
Journal of the European Academy of Dermatology and Venereology, 2022 The proportion of Merkel cell carcinomas (MCCs) in solid‐organ transplant recipients (SOTR) harbouring Merkel cell polyomavirus (MCPyV) is unknown, as are factors affecting their outcomes.
Carla Ferrándiz‐Pulido +24 more
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Quantification of human polyomaviruses MCPyV and HPyV6 in malignant and non-malignant skin lesions
Anais Brasileiros de Dermatologia, 2023 Background Human Polyomaviruses such as MCPyV and HPyV6 are frequently found as part of healthy skin microbiota and have been associated with Merkel cell carcinoma (MCC), pruritic and dyskeratotic dermatoses, respectively.
M. T. Venceslau +4 more
semanticscholar +4 more sources
Mast cell density in Merkel cell carcinoma and its correlation with prognostic features and MCPyV status: a pilot study [PDF]
Clinical and Experimental Medicine (Testo stampato)Merkel cell carcinoma (MCC) is a rare, highly aggressive, primitive neuroendocrine carcinoma of the skin, the origin of which is not yet fully understood.
Gerardo Cazzato +10 more
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Merkel Cell Polyomavirus (MCPyV) and Cancers: Emergency Bell or False Alarm?
Cancers, 2022 Simple Summary Merkel cell polyomavirus is a widespread pathogen, strongly associated with the highly aggressive Merkel cell carcinoma. In this review paper we aim to examine a possible association between Merkel cell polyomavirus and the emergence of ...
Maria Georgia Dimitraki, G. Sourvinos
semanticscholar +3 more sources
MCPyV Large T Antigen-Induced Atonal Homolog 1 Is a Lineage-Dependency Oncogene in Merkel Cell Carcinoma [PDF]
Journal of Investigative Dermatology, 2019 Despite the fact that the transcription factor atonal homolog 1 (ATOH1) is a master regulator of Merkel cell development, its role in Merkel cell carcinoma (MCC) carcinogenesis remains controversial.
Kaiji Fan +8 more
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Autologous MCPyV-specific HLA-A02-restricted TCR-transduced CD4 and CD8 T-cells FH-MCVA2TCR [PDF]
Definitions, 2020 A preparation of autologous CD4+ and CD62L-expressing CD8+ T -cells transduced with a third generation lentiviral vector (LV) to express the high affinity T -cell receptor (T CR) A2 -MCC1, specific for the human leucocyte antigen (HLA)-A02-restricted ...
National Cancer Institute
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PLoS ONE, 2017 Background The aim of this study was to determine the prevalence of MCPyV in Merkel cell carcinoma (MCC) primaries versus lymph node metastasis and to evaluate possible prognostic factors.
Georg Haymerle +9 more
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Antiviral regulator
International Journal of CancerMerkel cell carcinoma (MCC) is a highly aggressive neuroendocrine skin cancer, most often driven by integration of Merkel cell polyomavirus (MCPyV). While anti-PD-1/PD-L1 therapies have improved outcomes, reliable prognostic biomarkers remain limited ...
Klaus W. Fagerstedt +6 more
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Structural Analysis of Merkel Cell Polyomavirus (MCPyV) Viral Capsid Protein 1 (VP1) in HIV-1 Infected Individuals [PDF]
International Journal of Molecular Sciences, 2020 Merkel cell polyomavirus (MCPyV) viral protein 1 (VP1) is the capsid protein that mediates virus attachment to host cell receptors and is the major immune target.
Carla Prezioso +9 more
openalex +2 more sources
Investigation of mRNA expression levels of DNA damage response genes in Merkel Cell Polyomavirus-positive Merkel Cell Carcinoma: a pilot study [PDF]
Discover OncologyMerkel Cell Polyomavirus (MCPyV) is recognized as the major aetiological agent of Merkel Cell Carcinoma (MCC), an aggressive skin tumor. MCPyV-mediated oncogenesis is strictly dependent on viral integration and the expression of a truncated form of the ...
Sara Passerini +7 more
doaj +2 more sources