Results 51 to 60 of about 2,946 (205)

Detection of Merkel Cell Polyomavirus in Seborrheic Keratosis

Frontiers in Microbiology, 2018
Seborrheic keratosis (SK) is the most common benign cutaneous neoplasm. A subset shows increased p16 expression. Since SK shares several features with verruca vulgaris, e.g., increased p16 expression, human papillomaviruses (HPV) have been suggested as ...
Lisa M. Hillen, Dorit Rennspiess, Ernst-Jan Speel, Anke M. Haugg, Véronique Winnepenninckx, Axel zur Hausen   +5 more
doaj   +1 more source

Evaluation of Merkel Cell Polyomavirus DNA in Tissue Samples from Italian Patients with Diagnosis of MCC

Viruses, 2021
Because the incidence of Merkel cell carcinoma (MCC) has increased significantly during the last 10 years and it is recognized that Merkel cell polyomavirus (MCPyV) and ultraviolet (UV) radiation represent two different etiological inputs sharing ...
Carla Prezioso, Raffaella Carletti, Francisco Obregon, Francesca Piacentini, Anna Maria Manicone, Giuseppe Soda, Ugo Moens, Cira Di Gioia, Valeria Pietropaolo   +8 more
doaj   +1 more source

MCPyV DNA copy number.

, 2013
Relative quantification by QPCR of MCPyV DNA copies in eleven non irradiated skin samples from patient P18; normalization with GAPDH gene. Comparable results have been obtained with irradiated skin samples (data not shown).
Sébastien Corre (62241), Na Guo (198794), Alain Fautrel (209374), Laurent Misery (363611), Nicolas Mouchet (186275), Henri Adamski (248466), Eric Watier (248477), Ariane Mogha (149686), Marie-Dominique Galibert (62246)   +8 more
core   +1 more source

HATi treatment represses MCPyV EP-driven transcription.

, 2023
(A) HEK293 cells stably expressing an MCPyV EP-luciferase reporter were treated with DMSO, 2 μM A485, 1 μM NEO2734, 1 μM GNE-781, 1 μM CCS-1477, 10 μM C646, 10 μM SGC-CBP30, or 20 μM anacardic acid for 72h, then collected for luciferase or CellTiterGlo ...
Jianxin You (121729), June F. Yang (16907650), Wei Liu (20030)   +2 more
core   +1 more source

Characterization of ALTO-encoding circular RNAs expressed by Merkel cell polyomavirus and trichodysplasia spinulosa polyomavirus.

PLoS Pathogens, 2021
Circular RNAs (circRNAs) are a conserved class of RNAs with diverse functions, including serving as messenger RNAs that are translated into peptides. Here we describe circular RNAs generated by human polyomaviruses (HPyVs), some of which encode variants ...
Rong Yang, Eunice E Lee, Jiwoong Kim, Joon H Choi, Elysha Kolitz, Yating Chen, Clair Crewe, Nicholas J H Salisbury, Philipp E Scherer, Clay Cockerell, Taylor R Smith, Leslie Rosen, Louisa Verlinden, Denise A Galloway, Christopher B Buck, Mariet C Feltkamp, Christopher S Sullivan, Richard C Wang   +17 more
doaj   +1 more source

DNA Virus Detection in Olfactory Neuroblastomas Using Targeted Enrichment NGS

Neuropathology, Volume 46, Issue 2, April 2026.
ABSTRACT A variety of malignancies can be found in the sinonasal tract including the nasal cavity, paranasal sinuses, and skull base. Many of these are attributed to viruses, for example, carcinomas with the presence of transcriptionally active high‐risk human papillomavirus, as well as Epstein–Barr virus associated malignant lymphoepithelial carcinoma
Maria K. Jauhiainen, Outi I. Mielonen, Aaro Haapaniemi, Maria Söderlund‐Venermo, Jaana Hagström, Maria F. Perdomo, Saku T. Sinkkonen, Antti A. Mäkitie   +7 more
wiley   +1 more source

MCPyV VP1 epitope mapping of DSL.

, 2012
1H-NMR-spectra showing the binding epitope of DSL binding to MCPyV VP1 in solution. Top: DSL reference spectrum, bottom: STD spectrum in the presence of MCPyV VP1. Assignments are color-coded according to the DSL cartoon.
Bärbel S. Blaum (114952), Warren W. Wakarchuk (147276), Ursula Neu (147265), Akihiro Imamura (147278), Michel Gilbert (60775), Makoto Kiso (147280), Thilo Stehle (114963), Holger Hengel (147270), Niklas Arnberg (147281), Christopher B. Buck (121726), Thomas Peters (147287), Hiromune Ando (147279), Rachel M. Schowalter (121719), Dennis Macejak (147273), Robert L. Garcea (147283)   +14 more
core   +1 more source

Merkel cell Polyomavirus (MCPyV) in non-Merkel Cell Carcinoma (non-MCC) [PDF]

, 2023
Merkel cell polyomavirus (MCPyV) has been detected in respiratory specimens including those from Cystic Fibrosis (CF) patients, raising questions about its immunological and clinical relevance in the respiratory tract. MCPyV is considered the etiological
Prezioso, Carla
core  

Distinct merkel cell polyomavirus molecular features in tumour and non tumour specimens from patients with merkel cell carcinoma.

PLoS Pathogens, 2010
Merkel Cell Polyomavirus (MCPyV) is associated with Merkel Cell carcinoma (MCC), a rare, aggressive skin cancer with neuroendocrine features. The causal role of MCPyV is highly suggested by monoclonal integration of its genome and expression of the viral
Hélène C Laude, Barbara Jonchère, Eve Maubec, Agnès Carlotti, Eduardo Marinho, Benoit Couturaud, Martine Peter, Xavier Sastre-Garau, Marie-Françoise Avril, Nicolas Dupin, Flore Rozenberg   +10 more
doaj   +1 more source

The presence of Merkel cell carcinoma polyomavirus is associated with a distinct phenotype in neoplastic Merkel cell carcinoma cells and their tissue microenvironment.

PLoS ONE, 2020
AimsMerkel cell carcinoma (MCC) is an aggressive primary neuroendocrine tumor of the skin, associated with Merkel cell polyomavirus (MCPyV) in 49-89% of cases, depending on the country of origin and the techniques of detection.
María-Dolores Mendoza, Carlos Santonja, Carmen Gonzalez-Vela, Angel Concha, Nicolás Iglesias Pena, Eva-Maria Andrés-Esteban, Jose Pedro Vaque, Laura Cereceda, Raquel Pajares, H Kutzner, Luis Requena, Miguel A Piris   +11 more
doaj   +1 more source