Ultrastructural proof of polyomavirus in Merkel cell carcinoma tumour cells and its absence in small cell carcinoma of the lung. [PDF]
BACKGROUND: A new virus called the Merkel Cell Polyomavirus (MCPyV) has recently been found in Merkel Cell Carcinoma (MCC). MCC is a rare aggressive small cell neuroendocrine carcinoma primarily derived from the skin, morphologically indistinguishable ...
Charlotte T A H Wetzels +5 more
doaj +1 more source
Does a New Polyomavirus Contribute to Merkel Cell Carcinoma? [PDF]
A new technique designed to hunt for non-human transcripts has identified a novel SV40-like virus present in the majority of Merkel cell carcinomas.
DeCaprio, James A. +2 more
core +1 more source
Lymphotropism of Merkel Cell Polyomavirus Infection, Nova Scotia, Canada
To test the hypothesis that Merkel cell polyomavirus (MCPyV) can infect cells of the lymphoid system, we analyzed 353 specimens, including 152 non-Hodgkin lymphomas, 44 Hodgkin lymphomas, 110 benign lymph nodes, 27 lymph nodes with metastasis, and 20 ...
Sonia Toracchio +6 more
doaj +1 more source
Detection and characterization of two chimpanzee polyomavirus genotypes from different subspecies [PDF]
The complete nucleotide sequences of three chimpanzee polyomavirus genetic variants were determined. Phylogenetic analysis indicated that the viruses form two different genotypes of ChPyV.
Ilona Deuzing +6 more
core +1 more source
Detection of Merkel Cell Polyomavirus in Seborrheic Keratosis
Seborrheic keratosis (SK) is the most common benign cutaneous neoplasm. A subset shows increased p16 expression. Since SK shares several features with verruca vulgaris, e.g., increased p16 expression, human papillomaviruses (HPV) have been suggested as ...
Lisa M. Hillen +5 more
doaj +1 more source
The PP4R1 sub-unit of protein phosphatase PP4 is essential for inhibition of NF-kB by Merkel Polyomavirus small Tumour antigen [PDF]
Merkel cell carcinoma (MCC) is a highly aggressive skin cancer with a high metastatic potential. The majority of MCC cases are caused by the Merkel cell polyomavirus (MCPyV), through expression of the virus-encoded tumour antigens.
Agou +42 more
core +3 more sources
Frequent detection of human polyomavirus 6 in keratoacanthomas [PDF]
BACKGROUND: The recent discovery of the Merkel cell polyomavirus and its consistent association with Merkel cell carcinoma has drawn attention to the numerous recently discovered polyomaviruses and their possible involvement in the etiopathogenesis of ...
Anke Maria Haugg +9 more
core +1 more source
Merkel cell polyomavirus: molecular insights into the most recently discovered human tumour virus. [PDF]
A fifth of worldwide cancer cases have an infectious origin, with viral infection being the foremost. One such cancer is Merkel cell carcinoma (MCC), a rare but aggressive skin malignancy.
Abdul-Sada, H +7 more
core +3 more sources
DNA Virus Detection in Olfactory Neuroblastomas Using Targeted Enrichment NGS
ABSTRACT A variety of malignancies can be found in the sinonasal tract including the nasal cavity, paranasal sinuses, and skull base. Many of these are attributed to viruses, for example, carcinomas with the presence of transcriptionally active high‐risk human papillomavirus, as well as Epstein–Barr virus associated malignant lymphoepithelial carcinoma
Maria K. Jauhiainen +7 more
wiley +1 more source
Merkel Cell Polyomavirus (MCPyV) is associated with Merkel Cell carcinoma (MCC), a rare, aggressive skin cancer with neuroendocrine features. The causal role of MCPyV is highly suggested by monoclonal integration of its genome and expression of the viral
Hélène C Laude +10 more
doaj +1 more source

