Results 61 to 70 of about 3,161 (168)

MCPyV VP1 epitope mapping of DSL.

, 2012
1H-NMR-spectra showing the binding epitope of DSL binding to MCPyV VP1 in solution. Top: DSL reference spectrum, bottom: STD spectrum in the presence of MCPyV VP1. Assignments are color-coded according to the DSL cartoon.
Bärbel S. Blaum (114952), Warren W. Wakarchuk (147276), Ursula Neu (147265), Akihiro Imamura (147278), Michel Gilbert (60775), Makoto Kiso (147280), Thilo Stehle (114963), Holger Hengel (147270), Niklas Arnberg (147281), Christopher B. Buck (121726), Thomas Peters (147287), Hiromune Ando (147279), Rachel M. Schowalter (121719), Dennis Macejak (147273), Robert L. Garcea (147283)   +14 more
core   +1 more source

Merkel cell Polyomavirus (MCPyV) in non-Merkel Cell Carcinoma (non-MCC) [PDF]

, 2023
Merkel cell polyomavirus (MCPyV) has been detected in respiratory specimens including those from Cystic Fibrosis (CF) patients, raising questions about its immunological and clinical relevance in the respiratory tract. MCPyV is considered the etiological
Prezioso, Carla
core  

HATi treatment represses MCPyV EP-driven transcription.

, 2023
(A) HEK293 cells stably expressing an MCPyV EP-luciferase reporter were treated with DMSO, 2 μM A485, 1 μM NEO2734, 1 μM GNE-781, 1 μM CCS-1477, 10 μM C646, 10 μM SGC-CBP30, or 20 μM anacardic acid for 72h, then collected for luciferase or CellTiterGlo ...
Jianxin You (121729), June F. Yang (16907650), Wei Liu (20030)   +2 more
core   +1 more source

Robust Production of Merkel Cell Polyomavirus Oncogene Specific T Cells From Healthy Donors for Adoptive Transfer

Frontiers in Immunology, 2020
Virus positive Merkel cell carcinoma (VP-MCC) is an aggressive but immunogenic skin malignancy driven by Merkel cell polyomavirus (MCPyV) T antigen (TAg). Since adoptive T cell transfer (ACT) can be effective against virus-driven malignancies, we set out
Sarah I. Davies, Sarah I. Davies, Sarah I. Davies, John Barrett, Susan Wong, Mark Jesse Chang, Pawel J. Muranski, Pawel J. Muranski, Isaac Brownell   +8 more
doaj   +1 more source

DNA Virus Detection in Olfactory Neuroblastomas Using Targeted Enrichment NGS

Neuropathology, Volume 46, Issue 2, April 2026.
ABSTRACT A variety of malignancies can be found in the sinonasal tract including the nasal cavity, paranasal sinuses, and skull base. Many of these are attributed to viruses, for example, carcinomas with the presence of transcriptionally active high‐risk human papillomavirus, as well as Epstein–Barr virus associated malignant lymphoepithelial carcinoma
Maria K. Jauhiainen, Outi I. Mielonen, Aaro Haapaniemi, Maria Söderlund‐Venermo, Jaana Hagström, Maria F. Perdomo, Saku T. Sinkkonen, Antti A. Mäkitie   +7 more
wiley   +1 more source

Replication of Merkel cell polyomavirus (MCPyV) in human cell lines

, 2022
The Merkel cell polyomavirus (MCPyV) is the only human polyomavirus classified as probably carcinogenic to humans and is the causal factor of a rare aggressive skin malignancy the Merkel cell carcinoma (MCC) in around 80% of cases.
Bučková, Alžbeta
core  

Casein kinase 1α mediates phosphorylation of the Merkel cell polyomavirus large T antigen for β-TrCP destruction complex interaction and subsequent degradation

mBio
Merkel cell polyomavirus (MCPyV) is a double-stranded tumor virus that is the main causative agent of Merkel cell carcinoma (MCC). The MCPyV large T antigen (LT), an essential viral DNA replication protein, maintains viral persistence by interacting with
Alexander M. Pham, Hyun Jin Kwun
doaj   +1 more source

Novel human polyomaviruses, Merkel cell polyomavirus and human polyomavirus 9, in Japanese chronic lymphocytic leukemia cases

Journal of Hematology & Oncology, 2012
Background Chronic lymphocytic leukemia (CLL) is the rarest adult leukemia in Japan, whereas it is the most common leukemia in the Western world. Recent studies from the United States and Germany suggest a possible etiological association between Merkel ...
Imajoh Masayuki, Hashida Yumiko, Taniguchi Ayuko, Kamioka Mikio, Daibata Masanori   +4 more
doaj   +1 more source

Antigenic cross-reactivity among MCPyV-, BKPyV- and JCPyV-LPs.

, 2015
Hyperimmune sera were obtained from rats that were immunized with MCPyV-, BKPyV- and JCPyV-LPs, respectively. Titers of anti-MCPyV-, BKPyV- and JCPyV-LP-IgG were determined by ELISA.
Michiyo Kataoka (485324), Tetsuro Suzuki (180340), Noriyo Nagata (389752), Naokazu Takeda (290583), Kenji Iwasaki (352584), Harutaka Katano (249978), Kazumi Kobayashi (691493), Tetsuya Mizutani (58974), Takaji Wakita (109321), Tian-Cheng Li (691492)   +9 more
core   +1 more source

Prevalence of Merkel Cell Polyomavirus (MCPyV) in the Oral Cavity Biopsies in Northern Iran

, 2021
Objective: Infection with human tumor viruses is one of the hypothesized causes of cancer. The current investigation aimed to explore the presence and quantitative analysis of a new human tumor virus, Merkel cell polyomavirus (MCPyV)in tissue samples of ...
Chehrazi, M., Zebardast, A., Sadeghi, Farzin, Yahyapour, Yousef, Chehrazi, Mohammad, Hasanzadeh, Ali, Yahyapour, Y., Estalkhi, M.H., Sadeghi, F., Hasanzadeh, A., Hasani Estalkhi, Mina, Majidi, M.S., Zebardast, Arghavan, Seyed Majidi, Maryam   +13 more
core   +1 more source