Results 61 to 70 of about 2,946 (205)
Merkel cell polyomavirus and associated Merkel cell carcinoma
Tumour Virus Research, 2022 Merkel cell polyomavirus (MCPyV) is a ubiquitous skin infection that can cause Merkel cell carcinoma (MCC), a highly lethal form of skin cancer with a nearly 50% mortality rate.
June F. Yang, Jianxin You
doaj +1 more source
Replication of Merkel cell polyomavirus (MCPyV) in human cell lines
, 2022 The Merkel cell polyomavirus (MCPyV) is the only human polyomavirus classified as probably carcinogenic to humans and is the causal factor of a rare aggressive skin malignancy the Merkel cell carcinoma (MCC) in around 80% of cases.
Bučková, Alžbeta
core
Merkel cell polyomavirus small T antigen mRNA level is increased following in vivo UV-radiation. [PDF]
PLoS ONE, 2010 Merkel cell carcinoma (MCC) is a rare but aggressive skin cancer involving Merkel cells. Recently, a new human polyomavirus was implicated in MCC, being present in 80% of the samples analyzed.
Ariane Mogha +8 more
doaj +1 more source
International Journal of Cancer, Volume 158, Issue 3, Page 511-526, 1 February 2026.Abstract Viral infections play a significant role in cancer development, making detecting viral signatures a promising approach for early cancer diagnosis. Circulating free DNA (cfDNA), released into the bloodstream by tumors and other cells, has emerged as a powerful biomarker for non‐invasive cancer screening.
Richard Donkor Amponsah +4 more
wiley +1 more source
Antigenic cross-reactivity among MCPyV-, BKPyV- and JCPyV-LPs.
, 2015 Hyperimmune sera were obtained from rats that were immunized with MCPyV-, BKPyV- and JCPyV-LPs, respectively. Titers of anti-MCPyV-, BKPyV- and JCPyV-LP-IgG were determined by ELISA.
Michiyo Kataoka (485324) +9 more
core +1 more source
Frontiers in Oncology, 2022 IntroductionThere are numerous findings over the past decade have indicated that Merkel cell carcinoma (MCC) may have two pathways of pathogenesis: one related to ultraviolet irradiation and the other to the Merkel cell polyomavirus (MCPyV). However, the
Aimin Yang +5 more
doaj +1 more source
Tumor Immunotherapy and Microbiome: From Bench‐to‐Bedside Applications
MedComm, Volume 7, Issue 2, February 2026.The microbiome is related to the efficacy of immunotherapy and can be utilized to predict the efficacy and adverse reactions of immunotherapy. Microbiome‐targeted intervention strategies can improve the efficacy of ICI, but necessitating more comprehensive exploration.
Anqi Lin +12 more
wiley +1 more source
Competitive inhibition of seroreactivity between MCPyV, PtvPyV1 and PtvPyV2.
, 2014 ELISA Reactivity against MCPyV, PtvPyV1 and PtvPyV2 was determined for five human (A) and five chimpanzee (B) sera after preincubation with or without MCPyV, PtvPyV1 or PtvPyV VLPs. Percentage of inhibition after preincubation is indicated above bars.
Jérôme T. J. Nicol (561901) +6 more
core +1 more source
Ubiquitination dynamics in human tumour viruses: Viral infection, oncogenesis and antiviral therapy
The FEBS Journal, Volume 293, Issue 2, Page 325-347, January 2026.The ubiquitin system is essential for cellular homeostasis and regulates many processes. Viruses, including oncogenic ones, exploit or evade this system to survive and replicate. This review explores how human tumour viruses manipulate the ubiquitination system to complete their life cycle, evade immunity and promote cancer.
Oscar Trejo‐Cerro +2 more
wiley +1 more source
The Role of APOBEC3B in Cancer: Mechanisms, Clinical Challenges, and Therapeutic Opportunities
Human Mutation, Volume 2026, Issue 1, 2026.Apolipoprotein B mRNA editing enzyme catalytic polypeptide‐like 3B (APOBEC3B, A3B) is a key cytidine deaminase that induces genomic instability and clonal evolution in diverse malignancies. Although A3B plays a key role in the onset and advancement of various cancers, a comprehensive model bridging its multifaceted mechanisms and clinical translation ...
Fengfeng Zhou +3 more
wiley +1 more source