Results 11 to 20 of about 3,779 (167)

The influences of ApoE isoforms on endothelial adherens junctions and actin cytoskeleton responding to mCRP. [PDF]

Angiogenesis, 2023
Apolipoprotein E4 (ApoE4) plays an important role responding to monomeric C-reactive protein (mCRP) via binding to CD31 leading to cerebrovascular damage and Alzheimer’s disease (AD).
Zhang Z, Lin W, Gan Q, Lei M, Gong B, Zhang C, Henrique JS, Han J, Tian H, Tao Q, Potempa LA, Stein TD, Emili A, Qiu WQ.   +13 more
europepmc   +4 more sources

IgG4-related acute interstitial nephritis and the potential role of mCRP autoantibodies: a case report [PDF]

Renal Failure, 2019
Background: IgG4-related acute tubulointerstitial nephritis is a type of autoimmune-mediated interstitial nephritis. Recently, autoantibodies against modified C-reactive protein (mCRP) were found to play a pathogenic role in renal diseases through the ...
Lei Pu, Ping Zhang, Guisen Li
doaj   +4 more sources

pCRP-mCRP Dissociation Mechanisms as Potential Targets for the Development of Small-Molecule Anti-Inflammatory Chemotherapeutics [PDF]

Frontiers in Immunology, 2018
Circulating C-reactive protein (CRP) is a key acute-phase protein and one of the main clinical biomarkers for inflammation and infection. CRP is an important upstream mediator of inflammation and is associated with the onset of a number of important ...
V. Caprio, L. Badimón, M. Di Napoli, Wen-Hui Fang, G. Ferris, B. Guo, Rocco S. Iemma, Donghui Liu, Yasmin Zeinolabediny, M. Slevin   +9 more
semanticscholar   +8 more sources

Role of ischemic preconditioning in cardioprotective mechanisms of mCRP deposited myocardium in a rat model [PDF]

bioRxiv, 2020
The deposition of monomeric C-reactive protein (mCRP) in the myocardium aggravates ischemia-reperfusion injury (IRI) and myocardial infarction. Ischemic preconditioning (IPC) is known to protect the myocardium against IRI. We evaluated the effects of IPC
Eun Na Kim, Jae-Sung Choi, C. Kim, So Ra Kim, Ki-Bong Kim, S. Oh   +5 more
semanticscholar   +2 more sources

C-reactive protein dissociation drives choroidal neovascularization in age-related macular degeneration [PDF]

Scientific Reports
Choroidal neovascularization (CNV) and inflammation play an important role in retinal disease development and the acute phase reactant C-reactive protein (CRP) has been shown to contribute to Age-related macular degeneration (AMD) in vitro.
Maria Hernandez, Sara Romero-Vázquez, Sergio Recalde, Jaione Bezunartea, Maite Moreno Orduña, Idoia Belza-Zuazu, Alfredo García-Layana, Alfredo Adán, Patricia Fernández-Robredo, Blanca Molins   +9 more
doaj   +2 more sources

MCRP: Multiple Chain Routing Protocol for Energy Efficiency in Homogeneous Wireless Sensor Networks [PDF]

2019 International Conference on Advanced Science and Engineering (ICOASE), 2019
Wireless sensor networks (WSNs) comprise a wide variety of applications. In most of the applications, the sensor nodes are distributed in a hostile area and nodes in WSNs are energy constrained, once it is installed, it would be difficult to recharge the
Husam Kareem, S. Hashim, A. Sali, Omer W. Taha, I. J. Kazim, S. Shukri   +5 more
semanticscholar   +2 more sources

The plasma levels of mCRP is linked to cardiovascular disease in antineutrophil cytoplasmic antibody -associated vasculitis [PDF]

, 2020
Background C-reactive protein (CRP) has 2 natural isomers, C-reactive protein pentamer (pCRP) and C-reactive protein monomer (mCRP). The levels of CRP are significantly elevated in patients with anti-neutrophil cytoplasmic antibody（ANCA)-associated ...
Kaili Wu, Qinghui Liang, Na Ding, Bo-Wei Li, Jian Hao   +4 more
semanticscholar   +2 more sources

The Pathogenic Role of C-Reactive Protein in Diabetes-Linked Unstable Atherosclerosis. [PDF]

Int J Mol Sci
C-reactive protein (CRP) has long been recognized as a biomarker of systemic inflammation and cardiovascular disease (CVD) risk. However, emerging evidence highlights the distinct and potent pro-inflammatory role of its monomeric form (mCRP), which is ...
Sibianu M, Slevin M.
europepmc   +2 more sources

Monomeric C-reactive protein is associated with severity and prognosis of decompensated hepatitis B cirrhosis [PDF]

Frontiers in Immunology
C-reactive protein (CRP) is an acute-phase protein produced by the liver in response to infection and during chronic inflammatory disorders. Systemic inflammation is a major driver of cirrhosis progression from the compensated to the decompensated stage.
Ning Gao, Ping Yuan, Zhao-Ming Tang, Zhao-Ming Tang, Jia-Geng Lei, Ze-Rui Yang, Ze-Rui Yang, Mustafa Ahmed, Mustafa Ahmed, Zhen-Yu Yao, Dan Liang, Dan Liang, Yi Wu, Yi Wu, Hai-Yun Li, Hai-Yun Li   +15 more
doaj   +2 more sources

mCRP-Induced Focal Adhesion Kinase-Dependent Monocyte Aggregation and M1 Polarization, Which Was Partially Blocked by the C10M Inhibitor

International Journal of Molecular Sciences
Monomeric C-reactive protein (mCRP) has recently been implicated in the abnormal vascular activation associated with development of atherosclerosis, but it may act more specifically through mechanisms perpetuating damaged vessel inflammation and ...
Ylenia Pastorello, D. Manu, Xenia Sawkulycz, Vittorio Caprio, C. Bănescu, M. Dobreanu, L. Potempa, Mario Di Napoli, M. Slevin   +8 more
semanticscholar   +4 more sources