The influences of ApoE isoforms on endothelial adherens junctions and actin cytoskeleton responding to mCRP. [PDF]
Abstract Monomeric C-reactive protein (mCRP) plays a role in cerebrovascular damage mediated by apolipoprotein E4 (ApoE4) in Alzheimer's disease (AD) pathogenesis. Using proteomic profilings, we found altered cytoskeleton proteins in the microvasculature of AD brains, including increased levels of hyperphosphorylated tau (pTau) and the actin ...
Zhang Z +13 more
europepmc +3 more sources
Predicting Rainfall in the Context of Rainfall Derivatives Using Genetic Programming [PDF]
Rainfall is one of the most challenging variables to predict, as it exhibits very unique characteristics that do not exist in other time series data. Moreover, rainfall is a major component and is essential for applications that surround water resource ...
Alexandridis, Antonis +3 more
core +1 more source
Role of ischemic preconditioning in cardioprotective mechanisms of mCRP deposited myocardium in a rat model [PDF]
AbstractThe deposition of monomeric C-reactive protein (mCRP) in the myocardium aggravates ischemia-reperfusion injury (IRI) and myocardial infarction. Ischemic preconditioning (IPC) is known to protect the myocardium against IRI. We evaluated the effects of IPC on mCRP-deposited myocardium due to IRI in a rat model.
Kim, Eun Na +5 more
openaire +1 more source
Competition between distinct ApoE alleles and mCRP for the endothelial receptor CD31 differentially regulates neurovascular inflammation and Alzheimer’s disease pathology [PDF]
AbstractBACKGROUNDC-reactive protein (CRP) in peripheral inflammation is associated with increased Alzheimer’s disease (AD) risk in Apolipoprotein E4 (ApoE4), but not ApoE3 or E2, humans. It remains unknown whether peripheral monomeric CRP (mCRP) induces AD pathogenesis through some receptor of blood-facing endothelia in the brain in an ApoE genotype ...
Zhengrong Zhang +18 more
openaire +1 more source
FHR-1 binds to C-reactive protein and enhances rather than inhibits complement activation [PDF]
Factor H (FH)-related protein 1 (FHR-1) is one of the five human factor H-related proteins, which share sequence and structural homology with the alternative pathway complement inhibitor FH.
Bánlaki, Zsófia +7 more
core +1 more source
MCRP: Multiple Chain Routing Protocol for Energy Efficiency in Homogeneous Wireless Sensor Networks [PDF]
Wireless sensor networks (WSNs) comprise a wide variety of applications. In most of the applications, the sensor nodes are distributed in a hostile area and nodes in WSNs are energy constrained, once it is installed, it would be difficult to recharge the energy source of those sensor nodes.
Husam Kareem +5 more
openaire +1 more source
Wavelet feature extraction and genetic algorithm for biomarker detection in colorectal cancer data [PDF]
Biomarkers which predict patient’s survival can play an important role in medical diagnosis and treatment. How to select the significant biomarkers from hundreds of protein markers is a key step in survival analysis.
Aickelin, Uwe +3 more
core +3 more sources
Tubulointerstitial nephritis and uveitis syndrome : case report and review of the literature [PDF]
Purpose: To review the literature on tubulointerstitial nephritis and uveitis (TINU) syndrome, and to report a case of a patient with relapsing polychondritis (RP) and TINU syndrome. Method: TINU syndrome is a rare oculorenal inflammatory disorder.
Aguilar Sierra, Maria, Lonngi, Marcela
core +1 more source
MCRP Community Planning Graduate Studio 2005/06: King City Community Plan
During the current academic year, the City and Regional Planning Department graduate Community Planning Studio is engaged in important community-outreach that will make a difference in King City CA. Nuworsoo and Topping, the class instructors, resume the studio's pedagogy and do a brief discussion of the process and progress of this year's work in King
Nuworsoo, Cornelius, Topping, Kenneth
openaire +3 more sources
Serum C-reactive protein is an important and powerful prognostic biomarker in most adult solid tumors. [PDF]
INTRODUCTION:Prognostication in cancer is challenging and inaccurate. C-Reactive Protein (CRP), a cheap and sensitive marker of inflammation may help. This study investigated the relationship between CRP and prognosis in a large cohort of solid tumors ...
Shiva Shrotriya +9 more
doaj +1 more source

