Results 31 to 40 of about 1,814 (179)

Role of ischemic preconditioning in cardioprotective mechanisms of mCRP deposited myocardium in a rat model [PDF]

, 2020
Abstract The deposition of monomeric C-reactive protein (mCRP) in the myocardium aggravates ischemia-reperfusion injury (IRI) and myocardial infarction. Ischemic preconditioning (IPC) is known to protect the myocardium against IRI. We evaluated the effects of IPC on mCRP-deposited myocardium due to IRI in a rat model. Myocardial IRI was
Kim, Eun Na, Choi, Jae-Sung, Kim, Chong Jai, Kim, So Ra, Kim, Ki-Bong, Oh, Se Jin   +5 more
openaire   +1 more source

Image_1_mCRP as a Biomarker of Adult-Onset Still’s Disease: Quantification of mCRP by ELISA.tif

, 2022
BackgroundC-reactive protein (CRP) is a dynamic protein that undergoes conformational changes between circulating native pentameric CRP (pCRP), pentameric symmetrical forms (pCRP*) and monomeric (or modified) CRP (mCRP) forms.
Rino Homma (12985229), Masaaki Fujita (365351), Yasuo Sakurai (12985226), Cheng-Long Huang (3248166), Yuki Yasuda (5621375), Chitose Fujita (12985223)   +5 more
core   +1 more source

Monomeric C-Reactive Protein Localized in the Cerebral Tissue of Damaged Vascular Brain Regions Is Associated With Neuro-Inflammation and Neurodegeneration-An Immunohistochemical Study

Frontiers in Immunology, 2021
Monomeric C-reactive protein (mCRP) is now accepted as having a key role in modulating inflammation and in particular, has been strongly associated with atherosclerotic arterial plaque progression and instability and neuroinflammation after stroke where ...
Raid S. Al-Baradie, Shuang Pu, Shuang Pu, Donghui Liu, Yasmin Zeinolabediny, Glenn Ferris, Coral Sanfeli, Ruben Corpas, Elisa Garcia-Lara, Suliman A. Alsagaby, Bader M. Alshehri, Ahmed M. Abdel-hadi, Fuzail Ahmad, Psalm Moatari, Nima Heidari, Mark Slevin, Mark Slevin   +16 more
doaj   +1 more source

Representative CRP and mCRP immunostaining according to serum CRP levels.

, 2021
(A) Low serum CRP (≤0.1 mg/dL). (B) High serum CRP (1.39 mg/dL) (anti-CRP antibody, anti-mCRP antibody, × 40).
Chong Jai Kim (8828177), Eun Na Kim (3234693), Hee-Sung Ahn (823274), Se Jin Oh (8786870), So Ra Kim (11326717), Joon Seo Lim (3939407), Jae-Sung Choi (238255), Kyunggon Kim (414536), Jiyoung Yu (414538), Hwangkyo Jeong (11326714)   +9 more
core   +1 more source

Serum C-reactive protein is an important and powerful prognostic biomarker in most adult solid tumors. [PDF]

PLoS ONE, 2018
INTRODUCTION:Prognostication in cancer is challenging and inaccurate. C-Reactive Protein (CRP), a cheap and sensitive marker of inflammation may help. This study investigated the relationship between CRP and prognosis in a large cohort of solid tumors ...
Shiva Shrotriya, Declan Walsh, Amy S Nowacki, Cliona Lorton, Aynur Aktas, Barbara Hullihen, Nabila Benanni-Baiti, Katherine Hauser, Serkan Ayvaz, Bassam Estfan   +9 more
doaj   +1 more source

Competition between distinct ApoE alleles and mCRP for the endothelial receptor CD31 differentially regulates neurovascular inflammation and Alzheimer’s disease pathology [PDF]

, 2021
Abstract BACKGROUND C-reactive protein (CRP) in peripheral inflammation is associated with increased Alzheimer’s disease (AD) risk in Apolipoprotein E4 (ApoE4), but not ApoE3 or E2, humans. It remains unknown whether peripheral monomeric CRP (mCRP) induces AD pathogenesis through some receptor of ...
Zhengrong Zhang, Hana Na, Qini Gan, Qiushan Tao, Yuriy Alekseyev, Junming Hu, Zili Yan, Jack B. Yang, Hua Tian, Shenyu Zhu, Qiang li, Ibraheem M. Rajab, Jan Krizysztof Blusztajn, Benjamin Wolozin, Andrew Emili, Xiaoling Zhang, Thor Stein, Lawrence A. Potempa, Wei Qiao Qiu   +18 more
openaire   +1 more source

Representative microscopic images showing the patterns of CRP and mCRP immunopositivity in cases of abdominal aortic aneurysm.

, 2021
(A. anti-CRP antibody, B. anti-mCRP antibody, × 12.5). (TIF)
Chong Jai Kim (8828177), Eun Na Kim (3234693), Hee-Sung Ahn (823274), Se Jin Oh (8786870), So Ra Kim (11326717), Joon Seo Lim (3939407), Jae-Sung Choi (238255), Kyunggon Kim (414536), Jiyoung Yu (414538), Hwangkyo Jeong (11326714)   +9 more
core   +1 more source

Associations of C-reactive protein isoforms with systemic lupus erythematosus phenotypes and disease activity

Arthritis Research & Therapy, 2022
Background Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by a large production of autoantibodies and deficient clearance of cellular waste.
Jesper Karlsson, Jonas Wetterö, Maria Weiner, Johan Rönnelid, Rafael Fernandez-Botran, Christopher Sjöwall   +5 more
doaj   +1 more source

C-Reactive Protein in Atherosclerosis—More than a Biomarker, but not Just a Culprit

Reviews in Cardiovascular Medicine, 2023
C-reactive protein (CRP) is a pentraxin that is mainly synthesized in the liver in response to inflammatory cytokines. It exists in two functionally and structurally distinct isoforms.
Kürsat Kirkgöz
doaj   +1 more source

Image_1_Combination of anti-C1qA08 and anti-mCRP a.a.35-47 antibodies is associated with renal prognosis of patients with lupus nephritis.jpeg

, 2023
ObjectiveThe aim of this study is to explore the prevalence and clinicopathological associations between anti-C1qA08 antibodies and anti-monomeric CRP (mCRP) a.a.35-47 antibodies and to explore the interaction between C1q and mCRP.MethodsNinety patients ...
Xiao-Ling Liu (158848), Ying Tan (346135), Ming-Hui Zhao (160760), Shang-Rong Ji (598442), Feng Yu (273443)   +4 more
core   +1 more source