Viruses, 2021 Madin–Darby canine kidney (MDCK) cells are commonly used for the isolation of mammalian influenza A viruses. The goal of this study was to compare the sensitivity and suitability of the original MDCK cell line in comparison with MDCK-derived cell lines ...
Matthew Suderman +6 more
doaj +1 more source
Metabolites, 2023 Renal failure is a common chronic disease in dogs that substantially affects both their quality of life and longevity. The objective of this study was to assess the protective mechanisms of baicalin in cisplatin-induced Madin–Darby canine kidney (MDCK ...
Yao Wang +4 more
doaj +1 more source
Stable Ectopic Expression of ST6GALNAC5 Induces Autocrine MET Activation and Anchorage-Independence in MDCK Cells. [PDF]
PLoS ONE, 2016 The epithelial-mesenchymal transition (EMT) is a complex cancer progression that can boost the metastatic potential of transformed cells by inducing migration, loss of cell adhesion, and promoting proliferation under anchorage-independent conditions.
Chia Chu +3 more
doaj +1 more source
Cell Volume Fluctuations in MDCK Monolayers [PDF]
Biophysical Journal, 2015 Cells moving collectively in tissues constitute a form of active matter, in which collective motion depends strongly on driven fluctuations at the single-cell scale. Fluctuations in cell area and number density are often seen in monolayers, yet their role in collective migration is not known.
Steven M., Zehnder +4 more
openaire +3 more sources
Claudin-2 knockout by TALEN-mediated gene targeting in MDCK cells: claudin-2 independently determines the leaky property of tight junctions in MDCK cells. [PDF]
PLoS ONE, 2015 Tight junctions (TJs) regulate the movements of substances through the paracellular pathway, and claudins are major determinants of TJ permeability. Claudin-2 forms high conductive cation pores in TJs.
Shinsaku Tokuda, Mikio Furuse
doaj +1 more source
Comparison of different cell substrates on the measurement of human influenza virus neutralizing antibodies. [PDF]
PLoS ONE, 2012 Eight cell lines were systematically compared for their permissivity to primary infection, replication, and spread of seven human influenza viruses. Cell lines were of human origin (Caco-2, A549, HEp-2, and NCI-H292), monkey (Vero, LLC-MK2), mink (Mv1 Lu)
Weiguo Zhai +6 more
doaj +1 more source
Aquaporins differentially regulate cell‐cell adhesion in MDCK cells [PDF]
The FASEB Journal, 2019 ABSTRACT Plasticity of epithelial cell‐cell adhesion is vital in epithelial homeostasis and is regulated in multiple processes associated with cell migration, such as embryogenesis and wound healing. In cancer, cell‐cell adhesion is compromised and is associated with increased cell migration and metastasis ...
Login, Frédéric H. +6 more
openaire +3 more sources
Functional evaluation for adequacy of MDCK-lineage cells in influenza research
BMC Research Notes, 2019 Objective Influenza is an acute respiratory disease caused by the influenza virus which circulates annually in populations of different species. Madin-Darby Canine Kidney (MDCK) is the most widely utilized cell-line for conducting influenza research ...
Hsin-Chung Tsai +4 more
doaj +1 more source
The MDCK variety pack: choosing the right strain
BMC Cell Biology, 2011 The MDCK cell line provides a tractable model for studying protein trafficking, polarity and junctions (tight, adherens, desmosome and gap) in epithelial cells.
Chalmers Andrew D +2 more
doaj +1 more source
High yield production of influenza virus in Madin Darby canine kidney (MDCK) cells with stable knockdown of IRF7. [PDF]
PLoS ONE, 2013 Influenza is a serious public health problem that causes a contagious respiratory disease. Vaccination is the most effective strategy to reduce transmission and prevent influenza.
Itsuki Hamamoto +3 more
doaj +1 more source