Results 21 to 30 of about 12,124,912 (231)

Comparison of different cell substrates on the measurement of human influenza virus neutralizing antibodies. [PDF]

open access: yesPLoS ONE, 2012
Eight cell lines were systematically compared for their permissivity to primary infection, replication, and spread of seven human influenza viruses. Cell lines were of human origin (Caco-2, A549, HEp-2, and NCI-H292), monkey (Vero, LLC-MK2), mink (Mv1 Lu)
Weiguo Zhai   +6 more
doaj   +1 more source

Aquaporins differentially regulate cell‐cell adhesion in MDCK cells [PDF]

open access: yesThe FASEB Journal, 2019
ABSTRACT Plasticity of epithelial cell‐cell adhesion is vital in epithelial homeostasis and is regulated in multiple processes associated with cell migration, such as embryogenesis and wound healing. In cancer, cell‐cell adhesion is compromised and is associated with increased cell migration and metastasis ...
Login, Frédéric H.   +6 more
openaire   +3 more sources

Functional evaluation for adequacy of MDCK-lineage cells in influenza research

open access: yesBMC Research Notes, 2019
Objective Influenza is an acute respiratory disease caused by the influenza virus which circulates annually in populations of different species. Madin-Darby Canine Kidney (MDCK) is the most widely utilized cell-line for conducting influenza research ...
Hsin-Chung Tsai   +4 more
doaj   +1 more source

Serum-Free Suspension Culture of MDCK Cells for Production of Influenza H1N1 Vaccines

open access: yesPLoS ONE, 2015
Development of serum-free suspension cell culture processes is very important for influenza vaccine production. Previously, we developed a MDCK suspension cell line in a serum-free medium.
Ding Huang   +14 more
semanticscholar   +1 more source

High-throughput mRNA and miRNA profiling of epithelial-mesenchymal transition in MDCK cells

open access: yesBMC Genomics, 2015
Epithelial-mesenchymal transition (EMT) is an important process in embryonic development, especially during gastrulation and organ formation. Furthermore EMT is widely observed in pathological conditions, e.g., fibrosis, tumor progression and metastasis.
P. Shukla   +5 more
semanticscholar   +1 more source

The MDCK variety pack: choosing the right strain

open access: yesBMC Cell Biology, 2011
The MDCK cell line provides a tractable model for studying protein trafficking, polarity and junctions (tight, adherens, desmosome and gap) in epithelial cells.
Chalmers Andrew D   +2 more
doaj   +1 more source

Chitosan encapsulation modulates the effect of capsaicin on the tight junctions of MDCK cells

open access: yesScientific Reports, 2015
Capsaicin has known pharmacological effects including the ability to reversibly open cellular tight junctions, among others. The aim of this study was to develop a strategy to enhance the paracellular transport of a substance with low permeability (FITC ...
K. M   +8 more
semanticscholar   +1 more source

PrPC Undergoes Basal to Apical Transcytosis in Polarized Epithelial MDCK Cells. [PDF]

open access: yesPLoS ONE, 2016
The Prion Protein (PrP) is an ubiquitously expressed glycosylated membrane protein attached to the external leaflet of the plasma membrane via a glycosylphosphatidylinositol anchor (GPI).
Alexander Arkhipenko   +4 more
doaj   +1 more source

Signal transducing molecules and glycosyl-phosphatidylinositol-linked proteins form a caveolin-rich insoluble complex in MDCK cells

open access: yesJournal of Cell Biology, 1993
GPI-linked protein molecules become Triton-insoluble during polarized sorting to the apical cell surface of epithelial cells. These insoluble complexes, enriched in cholesterol, glycolipids, and GPI-linked proteins, have been isolated by flotation on ...
M. Sargiacomo   +3 more
semanticscholar   +1 more source

Contribution of multidrug and toxin extrusion protein 1 (MATE1) to renal secretion of trimethylamine-N-oxide (TMAO)

open access: yesScientific Reports, 2018
Trimethylamine-N-oxide (TMAO) gained considerable attention because of its role as a cardiovascular risk biomarker. Organic cation transporter 2 (OCT2) mediates TMAO uptake into renal proximal tubular cells.
A. Gessner, J. König, M. F. Fromm
doaj   +1 more source

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