Results 31 to 40 of about 12,124,912 (231)

Transepithelial Secretion of Mucosal IgM Mediated by Polymeric Immunoglobulin Receptor of Flounder (Paralichthys olivaceus): In-Vivo and In-Vitro Evidence

open access: yesFrontiers in Immunology, 2022
Secretory immunoglobulin (SIg) is crucial for mucosal surface defenses, but the transepithelial secretion of SIg mediated by polymeric immunoglobulin receptor (pIgR) is not clarified in fish.
Xiuzhen Sheng   +12 more
doaj   +1 more source

ZO-1 Knockout by TALEN-Mediated Gene Targeting in MDCK Cells: Involvement of ZO-1 in the Regulation of Cytoskeleton and Cell Shape

open access: yesPLoS ONE, 2014
ZO-1, ZO-2 and ZO-3 are tight junction-associated scaffold proteins that bind to transmembrane proteins of tight junctions and the underlying cytoskeleton.
Shinsaku Tokuda, T. Higashi, M. Furuse
semanticscholar   +1 more source

Cl- and regulation of pH by MDCK-C11 cells [PDF]

open access: yesBrazilian Journal of Medical and Biological Research, 2007
The interaction between H(+) extrusion via H(+)-ATPase and Cl(-) conductance was studied in the C11 clone of MDCK cells, akin to the intercalated cells of the collecting duct. Cell pH (pHi) was measured by fluorescence microscopy using the fluorescein-derived probe BCECF-AM.
Tararthuch, A.L.   +2 more
openaire   +5 more sources

TBC1D9B functions as a GTPase-activating protein for Rab11a in polarized MDCK cells

open access: yesMolecular Biology of the Cell, 2014
Rab11a is a key modulator of vesicular trafficking processes, but there is limited information about the GEFs and GAPs that regulate its GTP-GDP cycle.
Luciana I. Gallo   +9 more
semanticscholar   +1 more source

Regulation of caveolin and caveolae by cholesterol in MDCK cells [PDF]

open access: yesJournal of Lipid Research, 1998
We have examined the expression of caveolin in MDCK cells under conditions that vary cellular cholesterol concentration. Caveolin mRNA levels dropped to one-sixth of control levels after treatment with simvastatin, an inhibitor of cholesterol synthesis, or beta-trimethyl cyclodextrin (CD), a cholesterol sequestering drug.
Hailstones, D.   +3 more
openaire   +6 more sources

Regulation of Cell–Cell Adhesion by Rac and Rho Small G Proteins in MDCK Cells

open access: yesJournal of Cell Biology, 1997
The Rho small G protein family, consisting of the Rho, Rac, and Cdc42 subfamilies, regulates various cell functions, such as cell shape change, cell motility, and cytokinesis, through reorganization of the actin cytoskeleton.
K. Takaishi   +4 more
semanticscholar   +1 more source

Alpha1-Antitrypsin Attenuates Renal Fibrosis by Inhibiting TGF-β1-Induced Epithelial Mesenchymal Transition. [PDF]

open access: yesPLoS ONE, 2016
Alpha1-antitrypsin (AAT) exerts its anti-inflammatory effect through regulating the activity of serine proteinases. This study evaluated the inhibitory effects of AAT against the transforming growth factor (TGF)-β1 induced epithelial-to-mesenchymal ...
Jang-Hee Cho   +10 more
doaj   +1 more source

Receptor-mediated transcytosis of IgA in MDCK cells is via apical recycling endosomes

open access: yesJournal of Cell Biology, 1994
Classically, the polymeric immunoglobulin receptor and its ligand, IgA, are thought to be sorted from basolateral early endosomes into transcytotic vesicles that directly fuse with the apical plasma membrane. In contrast, we have found that in MDCK cells
G. Apodaca, L. Katz, K. Mostov
semanticscholar   +1 more source

Recycling endosomes can serve as intermediates during transport from the Golgi to the plasma membrane of MDCK cells

open access: yesJournal of Cell Biology, 2004
The AP-1B clathrin adaptor complex is responsible for the polarized transport of many basolateral membrane proteins in epithelial cells. Localization of AP-1B to recycling endosomes (REs) along with other components (exocyst subunits and Rab8) involved ...
A. Ang   +7 more
semanticscholar   +1 more source

APOPTOSIS STUDY OF INDONESIAN AVIAN INFLUENZA VIRUS SUBTYPE H5N1 IN MADIN-DARBY CANINE KIDNEY CELLS

open access: yesJurnal Kedokteran Hewan, 2017
This study aimed to determine the ability of highly pathogenic avian influenza virus (HPAI) virus subtype H5N1 originated from Indonesia to induce apoptosis in Madin-Darby Canine Kidney (MDCK) cells.
NLP Indi Dharmayanti   +3 more
doaj   +1 more source

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