Results 31 to 40 of about 33,145 (176)
Cl- and regulation of pH by MDCK-C11 cells [PDF]
The interaction between H(+) extrusion via H(+)-ATPase and Cl(-) conductance was studied in the C11 clone of MDCK cells, akin to the intercalated cells of the collecting duct. Cell pH (pHi) was measured by fluorescence microscopy using the fluorescein-derived probe BCECF-AM.
Tararthuch, A.L. +2 more
openaire +5 more sources
Trimethylamine-N-oxide (TMAO) gained considerable attention because of its role as a cardiovascular risk biomarker. Organic cation transporter 2 (OCT2) mediates TMAO uptake into renal proximal tubular cells.
A. Gessner, J. König, M. F. Fromm
doaj +1 more source
PrPC Undergoes Basal to Apical Transcytosis in Polarized Epithelial MDCK Cells. [PDF]
The Prion Protein (PrP) is an ubiquitously expressed glycosylated membrane protein attached to the external leaflet of the plasma membrane via a glycosylphosphatidylinositol anchor (GPI).
Alexander Arkhipenko +4 more
doaj +1 more source
Secretory immunoglobulin (SIg) is crucial for mucosal surface defenses, but the transepithelial secretion of SIg mediated by polymeric immunoglobulin receptor (pIgR) is not clarified in fish.
Xiuzhen Sheng +12 more
doaj +1 more source
Regulation of caveolin and caveolae by cholesterol in MDCK cells [PDF]
We have examined the expression of caveolin in MDCK cells under conditions that vary cellular cholesterol concentration. Caveolin mRNA levels dropped to one-sixth of control levels after treatment with simvastatin, an inhibitor of cholesterol synthesis, or beta-trimethyl cyclodextrin (CD), a cholesterol sequestering drug.
Hailstones, D. +3 more
openaire +6 more sources
Alpha1-Antitrypsin Attenuates Renal Fibrosis by Inhibiting TGF-β1-Induced Epithelial Mesenchymal Transition. [PDF]
Alpha1-antitrypsin (AAT) exerts its anti-inflammatory effect through regulating the activity of serine proteinases. This study evaluated the inhibitory effects of AAT against the transforming growth factor (TGF)-β1 induced epithelial-to-mesenchymal ...
Jang-Hee Cho +10 more
doaj +1 more source
APOPTOSIS STUDY OF INDONESIAN AVIAN INFLUENZA VIRUS SUBTYPE H5N1 IN MADIN-DARBY CANINE KIDNEY CELLS
This study aimed to determine the ability of highly pathogenic avian influenza virus (HPAI) virus subtype H5N1 originated from Indonesia to induce apoptosis in Madin-Darby Canine Kidney (MDCK) cells.
NLP Indi Dharmayanti +3 more
doaj +1 more source
Evidence for a prepore stage in the action of Clostridium perfringens epsilon toxin. [PDF]
Clostridium perfringens epsilon toxin (ETX) rapidly kills MDCK II cells at 37°C, but not 4°C. The current study shows that, in MDCK II cells, ETX binds and forms an oligomeric complex equally well at 37°C and 4°C but only forms a pore at 37°C.
Susan L Robertson +3 more
doaj +1 more source
Effect of human activated NRAS on replication of delNS1 H5N1 influenza virus in MDCK cells
Background RAS, coded by ras proto-oncogenes, played an important role in signal transmission to regulate cell growth and differentiation. Host activation of RAS was significant for IFN-sensitive vaccinia virus (delE3L) or attenuate influenza virus in ...
Zou Wei +3 more
doaj +1 more source
Src-family kinases, expressed in a wide variety of cell types, are anchored to cellular membranes through posttranslational lipid modifications and involved in diverse cellular signalling.
Takao Morinaga +4 more
doaj +1 more source

