Results 41 to 50 of about 12,124,912 (231)
Evidence for a prepore stage in the action of Clostridium perfringens epsilon toxin. [PDF]
PLoS ONE, 2011 Clostridium perfringens epsilon toxin (ETX) rapidly kills MDCK II cells at 37°C, but not 4°C. The current study shows that, in MDCK II cells, ETX binds and forms an oligomeric complex equally well at 37°C and 4°C but only forms a pore at 37°C.
Susan L Robertson +3 more
doaj +1 more source
Effect of human activated NRAS on replication of delNS1 H5N1 influenza virus in MDCK cells
Virology Journal, 2011 Background RAS, coded by ras proto-oncogenes, played an important role in signal transmission to regulate cell growth and differentiation. Host activation of RAS was significant for IFN-sensitive vaccinia virus (delE3L) or attenuate influenza virus in ...
Zou Wei +3 more
doaj +1 more source
Scientific Reports, 2017 Src-family kinases, expressed in a wide variety of cell types, are anchored to cellular membranes through posttranslational lipid modifications and involved in diverse cellular signalling.
Takao Morinaga +4 more
doaj +1 more source
Mechanisms of RON-mediated epithelial-mesenchymal transition in MDCK cells through the MAPK pathway
Brazilian Journal of Medical and Biological Research, 2011 The epithelial-mesenchymal transition (EMT) is involved in neoplastic metastasis, and the RON protein may be involved. In the present study, we determined the role and the mechanisms of action of RON in EMT in Madin-Darby canine kidney (MDCK) cells by ...
Xu Xiangming +4 more
doaj +1 more source
Ganglioside GM2 is substrate for a sialidase in MDCK cells
FEBS Letters, 1998 GM1 ganglioside carrying a fluorescent fatty acid in substitution of the natural one, has been administered to cultured Madin‐Darby canine kidney (MDCK) cells for different pulse times (0.5–24 h), and its metabolic fate was followed. The fluorescent GM2, asialo‐GM2, asialo‐GM1 and ceramide were the only detectable metabolites.
MARCHESINI, Sergio +4 more
openaire +2 more sources
Journal of Cell Biology, 1998 Membrane microdomains (“lipid rafts”) enriched in glycosylphosphatidylinositol (GPI)-anchored proteins, glycosphingolipids, and cholesterol have been implicated in events ranging from membrane trafficking to signal transduction.
A. Kenworthy, Michael Edidin
semanticscholar +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
FEBS Open Bio, 2019 Nuclear factor of activated T cells 5 (NFAT5) is a transcription factor involved in the regulation of several genes involved in the response to extracellular hyperosmolality. Recently, the uptake of ibuprofen by an as yet unknown carrier was suggested in
Rune Nørgaard Rasmussen +3 more
doaj +1 more source
Higher titers of some H5N1 and recent human H1N1 and H3N2 influenza viruses in Mv1 Lu vs. MDCK cells
Virology Journal, 2011 Background The infectivity of influenza A viruses can differ among the various primary cells and continuous cell lines used for such measurements. Over many years, we observed that all things equal, the cytopathic effects caused by influenza A subtype ...
Daniels Deirdre E +6 more
doaj +1 more source
Shear-induced Volume Decrease in MDCK Cells [PDF]
Cellular Physiology and Biochemistry, 2012 Using a microfluidic cell volume sensor we measured the change in the cell volume of Madin-Darby Canine Kidney (MDCK) cells induced by shear stress. An increase in shear stress from 0.2 to 2.0 dyn/cm(2) resulted in a volume decrease to a steady state volume ∼ 20 - 30 % smaller than the initial resting cell volume.
Jinseok, Heo +3 more
openaire +2 more sources