Results 1 to 10 of about 37,011 (292)

The Effect of Curcumin on Functional and Structural Alterations of the Liver in Rats after MDMA Consumption [PDF]

Journal of Kerman University of Medical Sciences, 2019
Background: Nowadays, one of the problems of human beings is drug addiction, which causes individual, economic and social damages. One of the most commonly used substances in parties is ecstasy pills or 3, 4-methylenedioxymethamphetamine (MDMA).
Naser Khalaji, Mohammad Hasan Khadem Ansari, Maryam Pourheydar, Mehdi Hasanpour, Sina Dindarian, Mehdi Bagheri, leila chodari   +6 more
doaj   +3 more sources

Safety pharmacology of acute MDMA administration in healthy subjects [PDF]

Journal of Psychopharmacology, 2017
3,4-Methylenedioxymethamphetamine (MDMA; ecstasy) is being investigated in MDMA-assisted psychotherapy. The present study characterized the safety pharmacology of single-dose administrations of MDMA (75 or 125 mg) using data from nine double-blind ...
Patrick Vizeli, Matthias E Liechti
exaly   +3 more sources

Pharmacogenetics of ecstasy: CYP1A2, CYP2C19, and CYP2B6 polymorphisms moderate pharmacokinetics of MDMA in healthy subjects [PDF]

, 2017
In vitro studies showed that CYP2C19, CYP2B6, and CYP1A2 contribute to the metabolism of 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) to 3,4-methylenedioxyamphetamine (MDA).
Liechti, Matthias E., Meyer Zu Schwabedissen, Henriette E., Prestin, Katharina, Schmid, Yasmin, Vizeli, Patrick   +4 more
core   +2 more sources

Motives for MDMA Use: A Comparative Study with Alcohol and Cannabis [PDF]

European Psychiatry
Introduction While research on drug use motives has primarily focused on widely used substances like alcohol, tobacco, and cannabis, understanding the motivations behind MDMA use is crucial for developing targeted therapeutic, preventive, and harm ...
D. Zullino, L. Penzenstadler, S. Rothen, F. Seragnnoli, A. S. Girardet, G. Calzada, G. Thorens   +6 more
doaj   +2 more sources

Adverse events in clinical treatments with serotonergic psychedelics and MDMA: A mixed-methods systematic review

Journal of Psychopharmacology, 2022
Joost J Breeksema, Eric H G J M Vermetten   +1 more
exaly   +3 more sources

Effect of MDMA exposure during pregnancy on cell apoptosis, astroglia, and microglia activity in rat offspring striatum [PDF]

Iranian Journal of Basic Medical Sciences, 2022
Objective(s): Ecstasy is a popular recreational psychostimulant with side effects on the central nervous system. This study examined the corpus striatum tissue of adult rats that received ecstasy during the embryonic period for histological and molecular
Zahra Nazari, Khadijeh Bahrebar, Mohammad Jafar Golalipour   +2 more
doaj   +1 more source

White matter alterations in chronic MDMA use: Evidence from diffusion tensor imaging and neurofilament light chain blood levels

NeuroImage: Clinical, 2022
3,4–Methylenedioxymethamphetamine (MDMA, “Ecstasy”) is a serotonin- and noradrenaline-releasing substance, currently among the most widely used illicit substances worldwide.
Josua Zimmermann, Nicole Friedli, Francesco Bavato, Philipp Stämpfli, Rebecca Coray, Markus R. Baumgartner, Denis Grandgirard, Stephen L. Leib, Antje Opitz, Erich Seifritz, Ann-Kathrin Stock, Christian Beste, David M. Cole, Boris B. Quednow   +13 more
doaj   +1 more source

MDMA-assisted therapy and current treatment options for chronic, treatment-resistant, moderate or higher severity post-traumatic stress disorder: Systematic literature review. [PDF]

PLoS One
Stanicic F, Zah V, Grbic D, Vukicevic D, de Angelo D.   +4 more
europepmc   +2 more sources

Role of the gut–brain axis via the subdiaphragmatic vagus nerve in stress resilience of 3,4-methylenedioxymethamphetamine in mice exposed to chronic restrain stress

Neurobiology of Disease, 2023
3,4-Methylenedioxymethamphetamine (MDMA) is the most widely used illicit substance worldwide. Nevertheless, recent observational studies demonstrated that lifetime MDMA use among U.S.
Youge Qu, Akifumi Eguchi, Li Ma, Xiayun Wan, Chisato Mori, Kenji Hashimoto   +5 more
doaj   +1 more source

MDMA ELECTROCHEMICAL DETERMINATION IN AQUEOUS MEDIA CONTAINING ILLICIT DRUGS AND VALIDATION OF A VOLTAMMETRIC METHODOLOGY

Drug Analytical Research, 2020
MDMA is the abbreviation for 3,4-methylenedioxymethamphetamine, which is commonly found in “ecstasy” pills. The psychoactive and euphoric effects that MDMA causes make this substance an illicit drug that is constantly seized by police forces. We describe
Juliana Midori Toia Katayama, Erica Naomi Oiye, Maria Fernanda Muzetti Ribeiro, Antônio José Ipólito, José Fernando de Andrade, Marcelo Firmino de Oliveira   +5 more
doaj   +1 more source