Results 41 to 50 of about 37,011 (292)
Evidence for selective executive function deficits in ecstasy/polydrug users [PDF]
, 2009 Previous research has suggested that the separate aspects of executive functioning are differentially affected by ecstasy use. Although the inhibition process appears to be unaffected by ecstasy use, it is unclear whether this is true of heavy users ...
Fisk, John, Montgomery, C.
core +1 more source
Journal of Neuroinflammation, 2011 Background Preconditioning is a phenomenon by which tolerance develops to injury by previous exposure to a stressor of mild severity. Previous studies have shown that single or repeated low dose MDMA can attenuate 5-HT transporter loss produced by a ...
Mayado Andrea +4 more
doaj +1 more source
Non-Serotonergic Neurotoxicity by MDMA (Ecstasy) in Neurons Derived from Mouse P19 Embryonal Carcinoma Cells. [PDF]
PLoS ONE, 2016 3,4-methylenedioxymethamphetamine (MDMA; ecstasy) is a commonly abused recreational drug that causes neurotoxic effects in both humans and animals. The mechanism behind MDMA-induced neurotoxicity is suggested to be species-dependent and needs to be ...
Dina Popova +3 more
doaj +1 more source
PLoS ONE, 2018 Methylenedioxymethamphetamine (MDMA) increases oxytocin, empathy, and prosociality. Oxytocin plays a critical role in emotion processing and social behavior and has been shown to mediate the prosocial effects of MDMA in animals. Genetic variants, such as
Patrick Vizeli, Matthias E Liechti
doaj +1 more source
An index of fatal toxicity for new psychoactive substances [PDF]
, 2018 The final, definitive version of this paper has been published in Journal of Psychopharmacology, February 2018, published by SAGE Publishing, All rights reserved.An index of fatal toxicity for new psychoactive substances has been developed based solely ...
Corkery, John, King, L.A.
core +2 more sources
The influence of genetic and environmental factors among MDMA users in cognitive performance. [PDF]
PLoS ONE, 2011 This study is aimed to clarify the association between MDMA cumulative use and cognitive dysfunction, and the potential role of candidate genetic polymorphisms in explaining individual differences in the cognitive effects of MDMA.
Elisabet Cuyàs +12 more
doaj +1 more source
Multifaceted empathy of healthy volunteers after single doses of MDMA: A pooled sample of placebo-controlled studies [PDF]
, 2017 Previous placebo-controlled experimental studies have shown that a single dose of MDMA can increase emotional empathy in the multifaceted empathy test (MET) without affecting cognitive empathy. Although sufficiently powered to detect main effects of MDMA,
Dolder, Patrick C. +3 more
core +2 more sources
Effects of ecstasy/polydrug use on memory for associative information [PDF]
, 2012 Rationale Associative learning underpins behaviours that are fundamental to the everyday functioning of the individual. Evidence pointing to learning deficits in recreational drug users merits further examination.
A Klugman +49 more
core +1 more source
Molecular Cages as Probes in Indicator Displacement Assays: The Case of Scopolamine Detection
Angewandte Chemie International Edition, EarlyView.In this research, we show the concept of molecular cages as probes in indicator displacement assays, focusing on scopolamine detection, a drug often used in drug‐facilitated sexual assaults. Drug sensing occurs via the drug‐induced transformation of non‐emissive [Fluorescein2⊂Cage] complex into [Scopolamine⊂Catenane] and highly emissive free ...
Giovanni Montà‐González +5 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aim The aim of this study was to develop a novel workflow to identify human urine biomarkers for drugs of abuse and new psychoactive substances. Metabolites of amphetamine, cocaine, LSD, MDMA, methamphetamine, THC, MDMB‐CHMICA, and MDPPP were first identified in a zebrafish embryo (ZE) metabolism study followed by comparison to most abundant human ...
Simon K. Wellenberg +7 more
wiley +1 more source