Results 211 to 220 of about 1,725,788 (328)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Mechanical stress on the rod in posterior spinal fusion with and without rod fracture: a finite element analysis. [PDF]

BMC Musculoskelet Disord
Inoue T, Kumano Y, Sugaya J, Okazaki K, Doi T.   +4 more
europepmc   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

CCDC141 is a Connectin/Titin and Nesprin-1 binding protein that adapts cardiomyocytes to mechanical stress. [PDF]

Commun Biol
Hanashima A, Kimoto M, Ujihara Y, Hashimoto K, Usui Y, Ohira M, Hoshino M, Uesugi K, Witt S, Labeit D, Kimura S, Murayama T, Sakurai T, Labeit S, Mohri S.   +14 more
europepmc   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Calcium waves and nuclear tension changes coordinate mechanical stress dissipation in locally folded epithelia. [PDF]

iScience
Brun-Cosme-Bruny M, Pernet L, Elias K, Guilluy C, Oddou C, Dolega ME.   +5 more
europepmc   +1 more source

Mechanical Stress Regulates Osteogenesis and Adipogenesis of Rat Mesenchymal Stem Cells through PI3K/Akt/GSK-3β/β-Catenin Signaling Pathway [PDF]

, 2017
Fanglong Song, Dawei Jiang, Tianchen Wang, Yi Wang, Yi Lou, Yinquan Zhang, Hui Ma, Yifan Kang   +7 more
openalex   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Mechanical Stress Reveals Asymmetry of Sodiation and Desodiation of Hard Carbon. [PDF]

ChemSusChem
Mück S, Kramer D, Palanisamy K, Kranz C, Mönig R.   +4 more
europepmc   +1 more source

Tuning stiffness of mechanical metamaterial unit cells via transitions to second-order rigid and pre-stressed states

Joseph C. Roback, Arya Nagrath, Sameera Kristipati, Christian D. Santangelo, Ryan C. Hayward   +4 more
openalex   +2 more sources