Results 201 to 210 of about 3,910,323 (355)

Remission spectroscopy resolves the mechanism of action of bedaquiline within living mycobacteria. [PDF]

Nat Commun
Harrison SH, Walters RC, Cheung CY, Springett RJ, Cook GM, Osman MM, Blaza JN.   +6 more
europepmc   +1 more source

Folates as adjuvants to anticancer agents: Chemical rationale and mechanism of action

, 2016
Peter V. Danenberg, Bengt Gustavsson, Patrick Johnston, Per Lindberg, Rudolf Moser, Elisabeth Odin, Godefridus J. Peters, Nicholas J. Petrelli   +7 more
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Theoretical-Experimental Analysis to Elucidate the Mechanism of Action of Novel Anabolic Agents. [PDF]

Molecules
Quiroga I, Cardenas-Garcia M, Hernández-Linares MG, Guerrero-Luna G, Flores-Manuel F.   +4 more
europepmc   +1 more source

Multisensory perception and action: development, decision-making, and neural mechanisms [PDF]

, 2013
Zhuanghua Shi, Hermann J. Müller
openalex   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Suzetrigine, a Non-Opioid Small-Molecule Analgesic: Mechanism of Action, Clinical, and Translational Science. [PDF]

Clin Transl Sci
Rajasingham R, Qi Y.
europepmc   +1 more source

Pigmented bioactive compounds from marine bacteria and their mechanisms of action involved in cytotoxicity

, 2012
Azamjon B. Soliev
openalex   +1 more source

Cognitive therapy as an early treatment for post‐traumatic stress disorder in children and adolescents: a randomized controlled trial addressing preliminary efficacy and mechanisms of action [PDF]

, 2016
Richard Meiser‐Stedman, Patrick Smith, Anna McKinnon, Clare Dixon, David Trickey, Anke Ehlers, David M. Clark, Adrian Boyle, Peter Watson, Ian Goodyer, Tim Dalgleish   +10 more
openalex   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source