Results 91 to 100 of about 9,819 (199)

The acute and chronic effects of local aerobic exercise on cardiovascular physiology

open access: yesExperimental Physiology, EarlyView.
Abstract Exercise training has beneficial effects for primary and secondary prevention of cardiovascular disease (CVD). Effects of exercise training have typically been studied in the form of whole‐body exercise training, partly driven by the assumption that larger effects of exercise training can be achieved by involving more and larger muscle groups.
Myrthe P. F. van de Ven   +3 more
wiley   +1 more source

Mechanosensing in Bone [PDF]

open access: yesClinical Reviews in Bone and Mineral Metabolism, 2010
The rationale for this issue of Clinical Reviews in Bone and Mineral Metabolism is rooted in the recognition of the revolution of the role of the osteocyte in bone biology. Since Wolff formulated his law of bone remodeling more than a century ago, the notion that mechanical function determines skeletal design and bone tissue organization has become ...
openaire   +2 more sources

Mathematical modeling of mechanosensitive reversal control in Myxococcus xanthus

open access: yesFrontiers in Microbiology
Adjusting motility patterns according to environmental cues is important for bacterial survival. Myxococcus xanthus, a bacterium moving on surfaces by gliding and twitching mechanisms, modulates the reversal frequency of its front-back polarity in ...
Yirui Chen   +6 more
doaj   +1 more source

Vascular smooth muscle cell mechanotransduction: Pathways, phenotypes and emerging technologies

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Vascular smooth muscle cells are exposed to mechanical stimuli from the blood flow and the extracellular matrix. The cells sense the signals from cyclic stretch, shear stress, hydrostatic pressure and matrix stiffness through specialized mechanosensors, such as mechanosensitive ion channels or cell surface receptors including ...
Nivethitha Kota Lakshminaraasimulu   +3 more
wiley   +1 more source

Piezo1 mechanosensing regulates integrin-dependent chemotactic migration in human T cells

open access: yeseLife
T cells are crucial for efficient antigen-specific immune responses and thus their migration within the body, to inflamed tissues from circulating blood or to secondary lymphoid organs, plays a very critical role. T cell extravasation in inflamed tissues
Chinky Shiu Chen Liu   +10 more
doaj   +1 more source

Generation of contractile actomyosin bundles depends on mechanosensitive actin filament assembly and disassembly

open access: yeseLife, 2015
Adhesion and morphogenesis of many non-muscle cells are guided by contractile actomyosin bundles called ventral stress fibers. While it is well established that stress fibers are mechanosensitive structures, physical mechanisms by which they assemble ...
Sari Tojkander   +4 more
doaj   +1 more source

Slit2/Robo Signaling Restores Diabetic Erectile Function via Neurovascular Remodeling

open access: yesAndrology, Volume 14, Issue 6, Page 1831-1846, September 2026.
ABSTRACT Background Diabetes mellitus‐induced erectile dysfunction (DMED) is a common and debilitating vascular‐neurogenic complication of diabetes. The poor responsiveness of DMED patients to phosphodiesterase type‐5 inhibitors underscores the need for therapies capable of restoring both endothelial integrity and cavernous nerve function.
Sen Fu   +7 more
wiley   +1 more source

The evolutionary origins of streptophyte multicellularity

open access: yesNew Phytologist, Volume 251, Issue 5, Page 2365-2383, September 2026.
The phylogeny of streptophytes and the deep origin of branching filamentous growth. Summary Over their more than 1 billion years of evolutionary history, streptophytes have repeatedly transitioned between unicellular, simple multicellular and complex multicellular forms.
Tatyana Darienko   +10 more
wiley   +1 more source

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