Results 101 to 110 of about 10,274 (232)

Piezo1 mechanosensing regulates integrin-dependent chemotactic migration in human T cells

eLife
T cells are crucial for efficient antigen-specific immune responses and thus their migration within the body, to inflamed tissues from circulating blood or to secondary lymphoid organs, plays a very critical role. T cell extravasation in inflamed tissues
Chinky Shiu Chen Liu, Tithi Mandal, Parijat Biswas, Md Asmaul Hoque, Purbita Bandopadhyay, Bishnu Prasad Sinha, Jafar Sarif, Ranit D'Rozario, Deepak Kumar Sinha, Bidisha Sinha, Dipyaman Ganguly   +10 more
doaj   +1 more source

Non‐Functionalized Graphene as an Electrical Sensing Surface for Bacterial Detection

Advanced Materials Interfaces, Volume 13, Issue 5, 4 March 2026.
Pathogenic bacteria detection in food remains a major public health concern, driving the need for rapid, cost‐effective, and portable detection systems. This review focuses on the use of non‐functionalized graphene as an electrical sensing surface for bacterial detection, highlighting their unique properties, sensing mechanism, and current developments.
Jazmin Berthe, Sara Giancaterino, Luciana Castillo, Cristiana Boi, Silvia Barbosa   +4 more
wiley   +1 more source

Hyperviscous Diabetic Bone Marrow Niche Impairs BMSCs Osteogenesis via TRPV2‐Mediated Cytoskeletal‐Nuclear Mechanotransduction

Advanced Science, Volume 13, Issue 13, 3 March 2026.
Diabetic bone marrow exhibits pathological ECM hyperviscosity that activates TRPV2‐mediated Ca2⁺ influx, leading to perinuclear F‐actin disassembly, nuclear deformation, and chromatin condensation. This cytoskeletal‐nuclear decoupling suppresses osteogenic differentiation of BMSCs.
Yao Wen, Xinhui Zheng, Jieliu Li, Minyu He, Dongqi Fan, Xingyu Zhu, Qiming Zhai, Liangjing Xin, Tao Chen   +8 more
wiley   +1 more source

A New Perspective in Nanocellulose‐Based Materials for Biomineralization and Strategies for Bone Repair

Journal of Biomedical Materials Research Part A, Volume 114, Issue 3, March 2026.
Nanocellulose‐based materials platform with the implementation of different bioactivation strategies for its potential use in hard tissue engineering (bone, tooth and cartilage). ABSTRACT Repairing large bone defects is a significant clinical challenge.
Jonathan Michel Barba Godinez, Ernesto Tinajero‐Díaz, Maria Soledad Peresin, Zaira Yunuen García Carvajal, Diego Gomez‐Maldonado   +4 more
wiley   +1 more source

Conformational Dynamics of the T-cell Receptor Chassis Coordinates CDR3 Loop Positioning during Mechanosensing of pMHC Ligands [PDF]

, 2020
Wonmuk Hwang, Robert J. Mallis, Matthew J. Lang, Ellis L. Reinherz   +3 more
openalex   +1 more source

Light‐Responsive Surface Topographies Modulate Macrophage Immune Responses Through Dynamic Mechanical Cues

Macromolecular Bioscience, Volume 26, Issue 3, March 2026.
This work introduces light‐responsive liquid crystal polymer films that generate dynamic, reversible topographies to modulate macrophage immune responses. By switching surface features on demand, we reveal macrophage plasticity, morphological adaptation, and mechanical memory.
Oksana K. Savchak, Ruth M. C. Verbroekken, Burcu Gumuscu, Albert P. H. J. Schenning   +3 more
wiley   +1 more source

Pre-T Cell Receptors (Pre-TCRs) Leverage Vβ Complementarity Determining Regions (CDRs) and Hydrophobic Patch in Mechanosensing Thymic Self-ligands [PDF]

, 2016
Dibyendu Kumar Das, Robert J. Mallis, Jonathan S. Duke‐Cohan, Rebecca E. Hussey, Paul W. Tetteh, Mark A. Hilton, Gerhard Wagner, Matthew J. Lang, Ellis L. Reinherz   +8 more
openalex   +1 more source

Carbon Dot‐Based Mechanofluorescent Hydrogel with Tunable Fluorescence for Bioengineering Applications

Small, Volume 22, Issue 14, 6 March 2026.
Hybrid hydrogels embedded with carbon‐based quantum dots (CQDs) exhibit real‐time fluorescence change in response to compressive force. These hydrogels demonstrate multifunctionality, biocompatibility, and tunable mechanofluorescent behavior, enabling advanced applications in soft robotics.
Elahe Masaeli, Poushali Das, Seshasai Srinivasan, Amin Reza Rajabzadeh   +3 more
wiley   +1 more source

A Role of Caveolae in Trabecular Meshwork Mechanosensing and Contractile Tone

, 2022
Michael L. De Ieso, Megan Kuhn, Pascal Bernatchez, Michael H. Elliott, W. Daniel Stamer   +4 more
openalex   +1 more source

Piezo1‐Mediated Mechanotransduction: Orchestrating the Dynamic Response of Podocytes and Parietal Epithelial Cells to Mechanical Stress

Acta Physiologica, Volume 242, Issue 3, March 2026.
ABSTRACT Aim The glomerulus is a specialized microvascular unit that filters plasma through the coordinated function of podocytes and parietal epithelial cells (PECs). From this perspective, the glomerulus functions like a living hydrogeological filtration system.
Maria Elena Melica, Giulia Antonelli, Anna Julie Peired, Laura Lasagni   +3 more
wiley   +1 more source