Results 31 to 40 of about 9,819 (199)
Cells, 2021 The magnitude of eosinophil mobilization into respiratory tissues drives the severity of inflammation in several airway diseases. In classical models of leukocyte extravasation, surface integrins undergo conformational switches to high-affinity states ...
Kiho Son +3 more
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WormBook, 2006 Wild C. elegans and other nematodes live in dirt and eat bacteria, relying on mechanoreceptor neurons (MRNs) to detect collisions with soil particles and other animals as well as forces generated by their own movement. MRNs may also help animals detect bacterial food sources.
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Nucleus Mechanosensing in Cardiomyocytes
International Journal of Molecular Sciences, 2023 Cardiac muscle contraction is distinct from the contraction of other muscle types. The heart continuously undergoes contraction–relaxation cycles throughout an animal’s lifespan. It must respond to constantly varying physical and energetic burdens over the short term on a beat-to-beat basis and relies on different mechanisms over the long term.
Isabella Leite Coscarella +5 more
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Mechanosensing: A Regulation Sensation [PDF]
Current Biology, 2015 Mechanosensing of surfaces in bacteria is a process that often uses obstruction of flagellum rotation to trigger behaviors such as adhesion and surface-associated movement. In a recent publication, the PilY1 protein of Pseudomonas aeruginosa has been implicated as a novel mechanosensor that stimulates virulence in response to surface attachment.
Ellison, Courtney, Brun, Yves V.
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Frontiers in Bioengineering and BiotechnologyWhile yes-associated protein (YAP) is now recognized as a potent mechanosensitive transcriptional regulator to affect cell growth and differentiation including the osteogenic transcription of mesenchymal stem cells (MSCs), most studies have reported the ...
Eunju Kim +7 more
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Dabbling with Piezo2 for mechanosensation [PDF]
Proceedings of the National Academy of Sciences, 2017 Nature has devised various strategies for sensing food so species can coexist and exploit different types of prey. Sharks can detect amino acids in blood as low as 1 ppb, while hawks and buzzards scan the Earth from a height of ∼10,000 feet looking for rodents. However, not all birds rely on their keen sense of sight to acquire food.
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Extracellular Matrix Components and Mechanosensing Pathways in Health and Disease
BiomoleculesGlycosaminoglycans (GAGs) and proteoglycans (PGs) are essential components of the extracellular matrix (ECM) with pivotal roles in cellular mechanosensing pathways.
Aikaterini Berdiaki +5 more
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Harnessing Mechanosensation in Next Generation Cardiovascular Tissue Engineering
Biomolecules, 2020 The ability of the cells to sense mechanical cues is an integral component of ”social” cell behavior inside tissues with a complex architecture. Through ”mechanosensation” cells are in fact able to decrypt motion, geometries and physical information of ...
Gloria Garoffolo +5 more
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Two-dimensional molecular condensation in cell signaling and mechanosensing
Acta Biochimica et Biophysica Sinica, 2023 Membraneless organelles (MLO) regulate diverse biological processes in a spatiotemporally controlled manner spanning from inside to outside of the cells.
Guo Xiangfu +4 more
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Advanced Functional Materials, EarlyView.A swelling‐programmed micropatterned hydrogel guides adherent cells through a controlled transition from cell–matrix anchoring to cadherin‐mediated cell–cell compaction, enabling rapid assembly of high‐viability spheroids with defined size and morphology.
Han Gyeol Nam +8 more
wiley +1 more source