Results 151 to 160 of about 43,729 (258)

The Stiff Side of Cancer: How Matrix Mechanics Rewrites Non-Coding RNA Expression Programs. [PDF]

Noncoding RNA
Campos-Parra AD, Puente-Rivera J, López-Camarillo C, Nuñez-Olvera SI, Hernández Nava N, Macias GA, Silva-Cázares MB.   +6 more
europepmc   +1 more source

Shaping Function: Polymeric 3D Systems With Unconventional Geometries for Biomedical Applications

Small, EarlyView.
Particle shape is a key design parameter governing biological interactions. Advances in fabrication enable precise control over anisotropy and compartmentalization, allowing modulation of cellular uptake, transport, and biodistribution, ultimately enhancing therapeutic performance. ABSTRACT Polymer geometry is a primary determinant of physical behavior
Francisca G. Perfeito, Mariana B. Oliveira, João F. Mano   +2 more
wiley   +1 more source

Mechanochemical regulation of organoid morphogenesis: Integrated signaling circuits in engineered microenvironments. [PDF]

Mater Today Bio
Zhang X, Zhao Y, Mao L, Wang Q, Huang P.
europepmc   +1 more source

Vertically Aligned Nanopillar Electrodes: Engineered Interfaces for Electrophysiology and Cell‐Electrode Coupling

Small Methods, EarlyView.
The graphic provides an overview of the emerging field of high‐surface area vertically aligned nanopillar electrodes for electrophysiological measurements. It depicts various types of electrodes; materials, and the methods used for fabrication of vertically aligned nanopillar electrodes.
Mohammad Alzahrani, Ismat Kabbara, Shuhua Peng, Hoang‐Phuong Phan, Tushar Kumeria   +4 more
wiley   +1 more source

The roles of the microtubule cytoskeletal network in cardiac mechanobiology. [PDF]

J Cell Sci
Murphy JF, Li X.
europepmc   +1 more source

Engineering Nanoscale Frontiers: Valve Metal Oxide Nanostructures From Fundamentals to Multifunctional Biomedical Applications

The Chemical Record, EarlyView.
Valve metal oxide nanostructures such as TiO2, Ta2O5, Nb2O5, ZrO2, and HfO2 are emerging as versatile biomedical platforms due to their tunable surface properties, exceptional stability, and inherent biocompatibility. This review highlights their synthesis, physicochemical properties, and biological interactions, addressing their roles in advanced ...
Nina Kummer, Désirée Gül, İdris Sargin, Mustafa Dolaz, Dzmitry Shcharbin, Shirley K. Knauer, Burcu Önal Acet, Emrah Dikici, Mingyuan Gao, Mehmet Odabaşı, Ömür Acet, Roland H. Stauber   +11 more
wiley   +1 more source

The Nemp1-Nesprin complex mediates cellular responses to matrix mechanics. [PDF]

Proc Natl Acad Sci U S A
Ganguly A, Zmuda H, Abello J, Illy D, Walter C, Tsatskis Y, Thanintorn N, Zhang Y, Hakim BA, Hodzic D, Stratman AN, Jurisicova A, Pathak A, McNeill H.   +13 more
europepmc   +1 more source

Decoding Dual Regulatory Layers: Integrating Differential Expression and Alternative Splicing Dynamics in the Evolution of Laryngeal Echolocation Across Chiropteran Lineages

Integrative Zoology, EarlyView.
We integrated short‐read and long‐read RNA‐seq data from cochlear tissues of echolocating and non‐echolocating bats to disentangle transcriptional and post‐transcriptional regulation. Echolocating bats showed neural‐function enrichment among differentially expressed genes, while alternatively spliced genes were linked to epigenetic regulation. Overlaps
Jianyu Wu, Daoyuan Hu, Min Chen, Xiuguang Mao   +3 more
wiley   +1 more source

Stress transmission towards the nucleus of the cell. [PDF]

Front Cell Dev Biol
Zhan Y, Shao S, Liu B, Yu X.
europepmc   +1 more source

Compartmentalisation in cAMP signalling: A phase separation perspective

British Journal of Pharmacology, EarlyView.
Cells rely on precise spatiotemporal control of signalling pathways to ensure functional specificity. The compartmentalisation of cyclic AMP (cAMP) and protein kinase A (PKA) signalling enables distinct cellular responses within a crowded cytoplasmic space.
Milda Folkmanaite, Manuela Zaccolo
wiley   +1 more source