Results 181 to 190 of about 43,729 (258)

Mechanical stiffness orchestrates distinct regulation of MRTFs and YAP/TAZ transcriptional cofactors in hepatocytes

The FEBS Journal, EarlyView.
MRTFs and YAP/TAZ proteins, or mechanosensitive transcriptional cofactors (MRTcoF), regulate common genes associated with cellular contractility and immune cell infiltration. Their differential regulation in response to stiffness is linked to changes in hepatocyte's aspect ratio. MRTFB does not undergo nuclear translocation under these conditions. This
Brenda Selene Torres‐Ortiz, Daniel Pérez‐Calixto, Jorge Carretero‐Ortega, Aida Gabriela Guzman‐López, Diana Cristina Pinto‐Dueñas, Mariana Hernández‐Juárez, Alejandra Jiménez‐Escobar, Adriana Rodríguez‐Hernández, Beatriz Díaz‐Bello, Nathalia Serna‐Márquez, Miguel Ángel Peña‐Rico, Laura Gómez‐Romero, Francisco Gabriel Vázquez‐Cuevas, Genaro Vázquez‐Victorio   +13 more
wiley   +1 more source

Mechanobiology in Stem Cell-Based Bioprinting. [PDF]

Cell Prolif
Ding S, Liu T, Yao R.
europepmc   +1 more source

Inflammation‐Regeneration Axis of Dental Pulp Stem Cells: Wnt/NF‐κB Crosstalk

International Endodontic Journal, EarlyView.
ABSTRACT Background Inflammation critically determines dental pulp regenerative outcomes, with dental pulp stem cells (DPSCs) orchestrating tissue homeostasis through differentiation, self‐renewal and immunomodulation processes dynamically regulated by Wnt/β‐catenin and NF‐κB signaling crosstalk.
V. Rajasekar, M. Huang, M. M. Abdalla, P. Neelakantan, C. K. Y. Yiu   +4 more
wiley   +1 more source

Pathogen-host infection modulated by mechanobiological cues in tissue microenvironments. [PDF]

Mechanobiol Med
Han Y, Duan X, Wang S, Huang S, Zhu K, Huang J.   +5 more
europepmc   +1 more source

A Unified Map of Airway Interactions: Secretome and Mechanotransduction Loops from Development to Disease. [PDF]

Adv Respir Med
Tugade C, Ramis J.
europepmc   +1 more source

Blood Mechanical Intelligence: From Force Sensing to Precision Mechanomedicine. [PDF]

Research (Wash D C)
Wang S, Pan T, Liu Q, Li Z, Wen T, Cheng B, Xu F, Yao C.   +7 more
europepmc   +1 more source

Tubule and microbranch variations in human dentine: A quantitative 3D study with serial block‐face scanning electron microscopy

Journal of Microscopy, EarlyView.
ABSTRACT Objective: Microbranches exist within dentine, providing a network of fluid filled connections between tubules. This study used serial block‐face scanning electron microscopy to generate 3D volumes of dentine from different tooth locations, allowing for investigations of the microbranch morphology, the microbranch network characteristics and ...
Bethany Harding, Patricia Goggin, James Thompson, Behrad Mahmoodi, Katy Rankin, Philipp Schneider, Richard Cook   +6 more
wiley   +1 more source

Reconstruction of native cellular microanatomy in a novel bioengineered full thickness human nasal mucosal construct

Journal of Anatomy, EarlyView.
Bioengineered tissue constructs are vital technologies employed in in vitro testing of both fundamental biological principles and industrial screening practices. Current approaches to modelling the nasal mucosa in vitro are not representative and are associated with limitations that impact their reliability and predictive value.
Steven Bradbury, Bethany Dickson, Nicola Curtis, David Bunton, Kirsty Goncalves, Stefan Przyborski   +5 more
wiley   +1 more source

Ventilator-Induced Lung Injury: Mechanotransduction and Potential Therapeutic Targets. [PDF]

MedComm (2020)
Ren H, Shang Z, Stewart AG, Qi YX, Huang K.   +4 more
europepmc   +1 more source