Results 111 to 120 of about 39,386 (288)
Under Pressure: Mechanical Stress Management in the Nucleus
Cells, 2016 Cells are constantly adjusting to the mechanical properties of their surroundings, operating a complex mechanochemical feedback, which hinges on mechanotransduction mechanisms.
Néjma Belaadi +2 more
doaj +1 more source
Bioinspired Adaptive Sensors: A Review on Current Developments in Theory and Application
Advanced Materials, EarlyView.This review comprehensively summarizes the recent progress in the design and fabrication of sensory‐adaptation‐inspired devices and highlights their valuable applications in electronic skin, wearable electronics, and machine vision. The existing challenges and future directions are addressed in aspects such as device performance optimization ...
Guodong Gong +12 more
wiley +1 more source
Steps in Mechanotransduction Pathways that Control Cell Morphology.
Annual Review of Physiology, 2019 It is increasingly clear that mechanotransduction pathways play important roles in regulating fundamental cellular functions. Of the basic mechanical functions, the determination of cellular morphology is critical.
Haguy Wolfenson, Bo Yang, M. Sheetz
semanticscholar +1 more source
A Soft Microrobot for Single‐Cell Transport, Spheroid Assembly, and Dual‐Mode Drug Screening
Advanced Materials, EarlyView.A soft, untethered hydrogel microrobot enables precise single‐cell delivery, self‐assembly into 3D spheroids, and real‐time thermal actuation. Driven by light‐induced convection and embedded with gold nanorods and temperature sensors, the microrobot guides cells, modulates local microenvironments, and supports drug testing.
Philipp Harder +3 more
wiley +1 more source
Control of cell differentiation by mechanical stress
Journal of Physical Fitness and Sports Medicine, 2013 Cells sense mechanical force and their physical environment to change their fate and behavior through mechanotransduction. The mechanotransduction is, by translating mechanical forces and deformations into biochemical intracellular signaling, changing ...
Jong-Hoon Park +2 more
doaj +1 more source
Poking Pluripotency: Nanoinjection Into Human iPSCs
Advanced Materials, EarlyView.Nanoinjection into hiPSCs: silicon nanotubes effectively transfect human induced pluripotent stem cells (hiPSCs) with mRNA, enabled by a delayed extracellular matrix application and enhanced surface functionalization. Nanoinjection is demonstrated with several reporter mRNA, including co‐transfection of mCherry and GFP.
Jann Harberts +5 more
wiley +1 more source
Mechanotransduction for therapeutic approaches: Cellular aging and rejuvenation
APL BioengineeringMechanotransduction regulates cytoskeletal remodeling, nuclear mechanics, and metabolic adaptation, which are central to cellular aging and rejuvenation.
Hye-Min Han, Su-Yeon Kim, Dong-Hwee Kim
doaj +1 more source
eLife, 2017 Hair cells of the cochlea are mechanosensors for the perception of sound. Mutations in the LRTOMT gene, which encodes a protein with homology to the catecholamine methyltransferase COMT that is linked to schizophrenia, cause deafness.
Christopher L Cunningham +7 more
doaj +1 more source
Advanced Materials Technologies, EarlyView.This study presents a novel platform for assessing the active mechanical behavior of living cardiac microbundles through localized nanoindentation, integrated with temperature regulation and dual‐camera imaging systems. The developed system enables quantitative evaluation of dynamic micromechanics in engineered cardiac tissues in vitro, offering ...
Lihua Lou +4 more
wiley +1 more source
Mechanobiology of bone remodeling and fracture healing in the aged organism
Innovative Surgical Sciences, 2016 Bone can adapt to changing load demands by mechanically regulated bone remodeling. Osteocytes, osteoblasts, and mesenchymal stem cells are mechanosensitive and respond to mechanical signals through the activation of specific molecular signaling pathways.
Haffner-Luntzer Melanie +2 more
doaj +1 more source