Results 11 to 20 of about 40,337 (298)
Mechanotransduction in Skin Inflammation
Cells, 2022 In the process of mechanotransduction, the cells in the body perceive and interpret mechanical stimuli to maintain tissue homeostasis and respond to the environmental changes.
Maria S. Shutova, Wolf-Henning Boehncke
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Mechanotransduction pathways in articular chondrocytes and the emerging role of estrogen receptor-α
Bone Research, 2023 In the synovial joint, mechanical force creates an important signal that influences chondrocyte behavior. The conversion of mechanical signals into biochemical cues relies on different elements in mechanotransduction pathways and culminates in changes in
Ning Wang +8 more
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A Hierarchical Mechanotransduction System: From Macro to Micro
Advanced Science, 2023 Mechanotransduction is a strictly regulated process whereby mechanical stimuli, including mechanical forces and properties, are sensed and translated into biochemical signals. Increasing data demonstrate that mechanotransduction is crucial for regulating
Rong Cao +3 more
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Physiological Reviews, 2023 This review aims to survey the current state of mechanotransduction in vascular smooth muscle cells (VSMCs) and endothelial cells (ECs), including their sensing of mechanical stimuli and transduction of mechanical signals that result in the acute ...
M. Davis +3 more
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Tuning immunity through tissue mechanotransduction
Nature Reviews Immunology, 2022 This Review considers how the biophysical properties of a tissue are able to shape immune cell function through the process of mechanotransduction. There are multiple mechanotransduction pathways that operate in immune cells and the authors highlight ...
Huixun Du +2 more
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Mechanotransduction gone awry [PDF]
Nature Reviews Molecular Cell Biology, 2009 Cells sense their physical surroundings through mechanotransduction - that is, by translating mechanical forces and deformations into biochemical signals such as changes in intracellular calcium concentration or by activating diverse signalling pathways. In turn, these signals can adjust cellular and extracellular structure.
Diana E Jaalouk, Jan Lammerding
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Integrin-mediated mechanotransduction [PDF]
Journal of Cell Biology, 2016 Sun, Guo, and Fässler review the function and regulation of integrin-mediated mechanotransduction and discuss how its dysregulation impacts cancer progession.
Zhiqi Sun, Shengzhen S Guo, R. Fässler
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Periodontal cell mechanotransduction [PDF]
Open Biology, 2018 The periodontium is a structurally and functionally complex tissue that facilitates the anchorage of teeth in jaws. The periodontium consists of various cell types including stem cells, fibroblasts and epithelial cells.
Sasanka S. Chukkapalli, Tanmay P. Lele
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Flow-mediated endothelial mechanotransduction. [PDF]
Physiological Reviews, 1995 Mechanical forces associated with blood flow play important roles in the acute control of vascular tone, the regulation of arterial structure and remodeling, and the localization of atherosclerotic lesions. Major regulation of the blood vessel responses occurs by the action of hemodynamic shear stresses on the endothelium.
P. Davies
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Lamins' role in osteosarcoma. [PDF]
Front Cell Dev BiolOsteosarcoma (OS) is a rare and highly aggressive bone tumor that can develop in several skeletal segments, although it predominantly affects the long bones. This cancer mostly occurs in adolescents, young adults and people older than 60.
Bagnato G, Peruzzi B.
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