Circadian Variation in the Median Effective Dose of Epidural Ropivacaine for Labor Analgesia [PDF]
Frontiers in Medicine, 2021 Background: Labor pain perception has been demonstrated to exhibit a circadian rhythm with lower pain scores during the day compared with the night. This study aimed to determine and compare the median effective dose (ED50) of ropivacaine in parturients ...
Jiali Deng +8 more
doaj +5 more sources
Median effective dose of esketamine for intranasal premedication in children with congenital heart disease [PDF]
BMC Anesthesiology, 2023 Background Esketamine is commonly used as a premedication for its sedation effect. However, the proper dosage for intranasal use in children with congenital heart disease (CHD) has not been determined.
Jiajia Huang +3 more
doaj +4 more sources
Median effective dose (ED50) of esketamine combined with propofol for children to inhibit response of gastroscope insertion [PDF]
BMC Anesthesiology, 2023 Background Propofol is the most commonly used drug for procedural sedation during gastroscopy. However, independent use of propofol can lead to increased dosage and additional side effects.
Ming Su +6 more
doaj +2 more sources
Median Effective Dose of Remifentanil for the Prevention of Pain Caused by the Injection of Rocuronium: An Age-Stratified Study [PDF]
Pain and Therapy, 2023 Introduction Rocuronium intravenous pain is common in induction of general anesthesia. The aim of our study was to determine the median effective dose (ED50) of prophylactic intravenous remifentanil for the prevention of rocuronium injection pain and to ...
Shiting Yan +8 more
doaj +2 more sources
The Effect of Dezocine on the Median Effective Dose of Sufentanil-Induced Respiratory Depression in Patients Undergoing Spinal Anesthesia Combined with Low-Dose Dexmedetomidine [PDF]
Drug Design, Development and Therapy, 2023 Yong-Kang Gui,1,2,* Xiao-Hui Zeng,1,2,* Rui Xiao,3 Wen-Feng Xi,1– 3 Dan Zhang,1– 3 Yang Liu,1,2 Si-Hui Zhu,1,2 Xin Da,1,2 De-Wen Shi,1,2 Xu-Dong Hu,1,2 Guang-Hong Xu1,2 1Department of Anesthesiology, the First Affiliated Hospital of Anhui Medical
Gui YK +10 more
doaj +2 more sources
The median effective dose of propofol combined with butorphanol during artificial abortion: a randomized controlled trial [PDF]
Frontiers in Medicine, 2023 ObjectivePropofol-opioids are the most common drug combination and can reduce the dose of propofol and the incidence of adverse events in painless artificial abortion.
Yuling Zheng +4 more
doaj +2 more sources
Determination of the median effective dose of sufentanil for inhibiting the laryngeal mask insertion response in geriatric patients: a prospective, double-blinded, dose–response trial [PDF]
BMC Anesthesiology, 2022 Background Laryngeal mask airway(LMA) have been widely used in clinical practice. Irritation to the patient during the insertion of a laryngeal mask can cause hemodynamic fluctuations, which is particularly unsafe for geriatric patients.
ShiFang Wang +5 more
doaj +2 more sources
Median effective dose of rocuronium for the prevention of succinylcholine-induced fasciculation: an age-stratified study [PDF]
BMC AnesthesiologyBackground Succinylcholine, a commonly used depolarizing neuromuscular blocking relaxant, may produce fasciculation and postoperative myalgia as adverse effects.
Shunping Tian +7 more
doaj +2 more sources
The median effective dose of esketamine with different doses of oliceridine during hysteroscopic surgery [PDF]
Frontiers in PharmacologyPurposeThis study aimed to investigate the impact of different doses of oliceridine on the ED50 of esketamine during hysteroscopic surgery. The objective was to establish an optimal dosing regimen that facilitates the development of an effective and safe
Min Shi +6 more
doaj +2 more sources
Determination of the median effective dose of sufentanil combined with remimazolam in inhibiting tracheal intubation response [PDF]
Scientific ReportsTo determine the median effective dose (ED50) and 95% effective dose (ED95) of sufentanil combined with remimazolam for inhibiting the tracheal intubation response in patients undergoing general anesthesia and to evaluate the hemodynamic stability and ...
Lin Feng +8 more
doaj +2 more sources