Results 31 to 40 of about 416,251 (201)

Determining the Median Effective Dose of Remimazolam for Anesthesia Induction in Patients Undergoing Endoscopic Retrograde Cholangiopancreatography: An Age-Stratified Study. [PDF]

Drug Des Devel Ther
Meng Y, Song Y, Gao C, Wang S, He K, Xu M.   +5 more
europepmc   +3 more sources

Effect of methotrexate on neurobehavior and cholinesterase in chicks [PDF]

Iraqi Journal of Veterinary Sciences, 2023
This reading aimed to determine the therapeutic index of methotrexate (MTX) with a note on the consequence of methotrexate in chicks on neurobehavioral in addition to calculating the activity for cholinesterase in plasma and brain in chicks.
Maab A. Fadel, Khayrea A. Mustafa, Imad A. Thanoon   +2 more
doaj   +1 more source

Determination of the Median Effective Dose of Dexmedetomidine for the Prevention of Emergence Agitation in Geriatric Patients Undergoing Major Open Surgery With General Anesthesia: A Prospective, Double-Blinded, Dose-Response Trial. [PDF]

Dose Response, 2021
Wang W, Zhou H, Sun A, Xiao J, Dong J, Xu H.   +5 more
europepmc   +3 more sources

The Median Effective Dose of Dexmedetomidine for the Inhibition of Emergence Delirium in Preschool Children Undergoing Tonsillectomy and/or Adenoidectomy: A Retrospective Dose-response Trial. [PDF]

Dose Response
Wei B, Yu C, Xiao J, Xu H, Zheng P, Wang W.   +5 more
europepmc   +3 more sources

Assessing a 6-h endpoint observation time in the lethality neutralization assay used to evaluate the preclinical efficacy of snake antivenoms

Toxicon: X, 2021
The lethality neutralization assay in mice is the gold standard for the evaluation of the preclinical efficacy and specification fulfillment of snake antivenoms. However, owing to the animal suffering involved, this assay is a candidate to be replaced by
Gina Durán, Gabriela Solano, Aarón Gómez, Daniel Cordero, Adriana Sánchez, Mauren Villalta, Melvin Sánchez, Cecilia Díaz, José María Gutiérrez, Guillermo León   +9 more
doaj   +1 more source

ED50 of Propofol Combined with Nalbuphine on the Sedative Effect in Painless Hysteroscopy

Pain and Therapy, 2021
Introduction Nalbuphine has gradually become a commonly used clinical analgesic drug for painless hysteroscopy. The aim of our study was to identify the median effective dose (ED50) of propofol combined with nalbuphine for painless hysteroscopy.
Chen Chen, Weixiang Tang, Wei Ye, Weiwei Zhong, Yuanhai Li   +4 more
doaj   +1 more source

Determining the Median Effective Dose of Remimazolam for Anesthesia Induction in Patients Undergoing Endoscopic Retrograde Cholangiopancreatography: An Age-Stratified Study

Drug Design, Development and Therapy
Yan Meng, Youping Song, Chen Gao, Sheng Wang, Keqiang He, Min Xu Department of Anesthesiology, the First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, People’s Republic ...
Meng Y, Song Y, Gao C, Wang S, He K, Xu M   +5 more
doaj   +1 more source

Determination of pesticide toxicity parameters using probit-analysis

Карантин і захист рослин, 2023
Goal of the research is to consider the main concepts used in the probit-analysis method, the features of its application to determine the toxicity of pesticides, in particular insecticides, acaricides and fungicides. Methods.
O. Shevchuk, O. Vlasova, I. Shevchuk, Yu. Stefkivska   +3 more
doaj   +1 more source

ED50 and ED95 of Propofol Combined with Different Doses of Intravenous Lidocaine for First-Trimester Uterine Aspiration: A Prospective Dose-Finding Study Using Up-and-Down Sequential Allocation Method

Drug Design, Development and Therapy, 2022
Jingwen Zhang,1 Linglingli Kong,2 Juan Ni1 1Department of Anesthesiology, West China Second University Hospital, Sichuan University, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Sichuan University, Ministry of Education ...
Zhang J, Kong L, Ni J
doaj  

Evaluating Antivenom Efficacy against Echis carinatus Venoms—Screening for In Vitro Alternatives

Toxins, 2022
In India, polyvalent antivenom is the mainstay treatment for snakebite envenoming. Due to batch-to-batch variation in antivenom production, manufacturers have to estimate its efficacy at each stage of IgG purification using the median effective dose ...
Siddharth Bhatia, Avni Blotra, Karthikeyan Vasudevan   +2 more
doaj   +1 more source