Results 71 to 80 of about 1,007,590 (275)

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Electron microscopic immunohistochemical localization of growth hormone‐release inhibiting hormone (somatostatin) in the rat median eminence

, 1974
Using an immunohistochemical technique at the electron microscopic level, we have observed that growth hormone‐release inhibiting hormone (somatostatin), the hormone which inhibits the release of growth hormone, is contained in the secretory granules of ...
Schally, Andrew V, Labrie, Fernand, Arimura, Akira, Pelletier, Georges   +3 more
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Characterization of GFAP expression and cell proliferation in the rat median eminence following hypophysectomy [PDF]

, 2011
To analyze whether the reorganization of the rat median eminence after hypophysectomy might be related to changes in glial fibrillary acidic protein (GFAP)- and cellular proliferation, the distribution of cells immunoreactive for GFAP and the ...
Carretero, J., Hernández, E., Vázquez, G., Riesco, J. M., Vázquez, R., Santos, M., Juanes, J. A., Blanco, E., Sánchez, F., Rubio, M.   +9 more
core   +2 more sources

Prolactin Signalling in the Median Eminence in the Mouse

, 2016
The median eminence represents the interface between the hypothalamus and the portal blood, allowing access to the anterior pituitary and thus regulation of its secretion. The structure of the blood brain barrier at the median eminence is highly modified
Kirk, Siobhan Emma
core   +1 more source

Identification of cGnRH-II in the median eminence of Japanese quail (Coturnix coturnix japonica)

, 2003
In a previous paper, we described the presence of cGnRH-II in the quail (Coturnix coturnix japonica) and chicken (Gallus gallus) median eminence using highly specific antibodies directed against a polypeptide corresponding to the C-terminal portion of ...
Clerens, Stefan, Arckens, Lut, Berghman, Luc R., D'Hondt, Els, Vandesande, Frans   +4 more
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

The LepR-mediated leptin transport across brain barriers controls food reward

Molecular Metabolism, 2018
Objective: Leptin is a key hormone in the control of appetite and body weight. Predominantly produced by white adipose tissue, it acts on the brain to inhibit homeostatic feeding and food reward.
Alessandro Di Spiezio, Elvira Sonia Sandin, Riccardo Dore, Helge Müller-Fielitz, Steffen E. Storck, Mareike Bernau, Walter Mier, Henrik Oster, Olaf Jöhren, Claus U. Pietrzik, Hendrik Lehnert, Markus Schwaninger   +11 more
doaj   +1 more source

[News Clip: His Eminence]

, 1959
Video footage from the WBAP-TV television station in Fort Worth, Texas, to accompany a news story about the Greek Orthodox Archbishop of North and South America, His Eminence Iakovos, visiting North ...
WBAP-TV (Television station : Fort Worth, Tex.)
core  

Identification of kainate-preferring glutamate receptor subunit G1uR7 mRNA and protein in the rat median eminence

, 1998
In situ hybridization and immunohistochemistry were used to determine the presence of kainate-preferring glutamate receptor subunits GluR6 and GluR7 mRNA and protein in the median eminence of the rat.
Jennes, Lothar
core   +1 more source