Results 11 to 20 of about 59,578 (214)

The new algorithm for calculation of median lethal dose (LD50) and effective dose fifty (ED50) of Micrarus fulvius venom and anti-venom in mice [PDF]

open access: yesInternational Journal of Veterinary Science and Medicine, 2016
One million people throughout the world are bitten yearly by poisonous snakes. Of this, one-tenth died and three-tenth suffer some forms of disabilities.
Saganuwan Alhaji Saganuwan
doaj   +4 more sources

Median Lethal Dose, Antimalarial Activity, Phytochemical Screening and Radical Scavenging of Methanolic Languas galanga Rhizome Extract [PDF]

open access: yesMolecules, 2010
The methanolic extract of Languas galanga rhizomes was investigated for antimalarial activity against Plasmodium berghei (NK65) infections in mice. The median lethal dose was determined to ascertain the safety of the extract in ICR mice of both sexes ...
Abdulelah H. Al-Adhroey   +3 more
doaj   +2 more sources

Determination of the Median Lethal Dose and Electrophoretic Pattern of Hottentotta saulcyi (Scorpiones, Buthidae) Scorpion Venom [PDF]

open access: yesJournal of Arthropod-Borne Diseases, 2015
Background: In this study, we investigated the lethal potency, electrophoretic protein pattern and in vivo effects of Hottentotta saulcyi scorpion venom in mice. Methods: Scorpions were collected at night, by using a UV lamp from Mardin Province, Turkey.
ErsenAydın Yağmur   +2 more
doaj   +1 more source

Adenylate cyclase affects the virulence of extraintestinal pathogenic escherichia coli derived from sheep lungs [PDF]

open access: yesKafkas Universitesi Veteriner Fakültesi Dergisi, 2023
Escherichia coli is an important component of the normal bacterial community in humans and animals. However, in recent years, the pathogenicity of some virulent strains to the outside of the intestine has been confirmed in clinical medicine.
Yingjin CHAI   +10 more
doaj   +1 more source

Determination of the median lethal dose of indoxacarb pesticide in Wistar rat [PDF]

open access: yesJournal of Veterinary and Animal Sciences, 2023
Indoxacarb is a novel organophosphate substitute and is considered a “lower risk” pesticide in agriculture. However, in humans and animals, indoxacarb exposure had been linked to substantial health problems.
Archana Raj   +5 more
doaj   +1 more source

Does Bacillus thuringiensis Affect the Stress and Immune Responses of Rhynchophorus ferrugineus Larvae, Females, and Males in the Same Way?

open access: yesInsects, 2022
Bacillus thuringiensis (Bt) is considered a potentially useful entomopathogen against red palm weevil (RPW) Rhynchophorus ferrugineus. We compared the effects of Bt on mature larvae, females, and males.
Monica Celi   +4 more
doaj   +1 more source

Calculation of the Median Lethal Dose and Low Lethal Dose Using the CombiStats Biometric Software

open access: yesРегуляторные исследования и экспертиза лекарственных средств, 2021
The median lethal dose (LD50) and low lethal dose (LD10) are calculated in acute toxicity studies, as well as during specific activity assessment of some medicines.
P. V. Shadrin   +3 more
doaj   +1 more source

Research Note: Evaluation of acute oral toxicity of povidone-iodine in cockerels using the up-and-down procedure

open access: yesPoultry Science, 2021
Povidone-iodine (Polidine) is a synthetic broad-spectrum antiseptic and being applied topically to treat wounds and prevent their infection. It is however used by poultry farmers, field veterinarians, and other animal health workers with the claim that ...
D. Sani   +5 more
doaj   +1 more source

Median lethal Dose and Acute Toxicity of Rosa canina L: In-Vivo Study

open access: yesAl-Mustansiriyah Journal of Pharmaceutical Sciences, 2022
Rosa canina belongs to rosacea family. Rosa. canina has a high concentration of phyto-constituents such as flavonoids, carotenoids, triterpene and vitamins as vitamin C, E, and A Rosa canina have an anti-inflammatory and antioxidant   effects. The
Zaman Mahmood Jasim   +2 more
doaj   +1 more source

Assessing a 6-h endpoint observation time in the lethality neutralization assay used to evaluate the preclinical efficacy of snake antivenoms

open access: yesToxicon: X, 2021
The lethality neutralization assay in mice is the gold standard for the evaluation of the preclinical efficacy and specification fulfillment of snake antivenoms. However, owing to the animal suffering involved, this assay is a candidate to be replaced by
Gina Durán   +9 more
doaj   +1 more source

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