Results 21 to 30 of about 59,578 (214)

Toxicity studies of drugs and chemicals in animals: An overview [PDF]

open access: yesBulgarian Journal of Veterinary Medicine, 2017
Toxicity study is the investigation of either short or long-term toxic effects of a drug or chemical on animals. The toxicity is dose-dependent as asserted by Paracelsus over 500 years ago.
S. Saganuwan
doaj   +1 more source

Determination of median embryo lethal dose for a velogenic Newcastle disease virus isolated in Sulaimani/Iraq [PDF]

open access: yesBasrah Journal of Veterinary Research, 2023
 Newcastle disease (ND) is an endemic viral illness in Iraq and has four types: viscerotropic velogenic, neurotropic velogenic, mesogenic, and lentogenic.
Hiewa Dyary   +3 more
doaj   +1 more source

Determination of pesticide toxicity parameters using probit-analysis

open access: yesКарантин і захист рослин, 2023
Goal of the research is to consider the main concepts used in the probit-analysis method, the features of its application to determine the toxicity of pesticides, in particular insecticides, acaricides and fungicides. Methods.
O. Shevchuk   +3 more
doaj   +1 more source

John William Trevan’s concept of Median Lethal Dose (LD50/LC50) – more misused than used

open access: yesJournal of Pre-Clinical and Clinical Research, 2021
Introduction Median lethal dose (MLD) has been a controversial subject among biologists and animal ethicists since its inception in 1927 by Trevan. Toxicologists use MLD (LD50) as the first step to assess the toxicity of a substance.
Sadasivan Kalathil Pillai   +5 more
doaj   +1 more source

Evaluation of the acute hepatotoxicity of Medemia argun seed's extract by determining of LD50 value and dose response curve. [PDF]

open access: yesAlfarama Journal of Basic & Applied Sciences, 2020
Determination of median lethal dose (LD50) is one way to measure the potential short-term toxicity (acute toxicity) of a substance to a biological system that sufficient to kill 50 percent of a population of tested animals.
amal ahmed   +3 more
doaj   +1 more source

Acute and sub-chronic toxicity evaluation of the crude methanolic extract of Diospyros mespiliformis hochst ex a. Dc (ebenaceae) and its fractions

open access: yesToxicology Reports, 2020
Diospyros mespiliformis, commonly called Jackal berry or African ebony, belongs to the plant family, Ebenaceae. The roots, barks and leaves have been used traditionally to treat wide varieties of conditions, however, there is limited information and ...
A.A. Ebbo   +4 more
doaj   +1 more source

Identification and characterization of Aeromonas veronii and Vibrio cholerae from naturally diseased red swamp crayfish (Procambarus clarkia)

open access: yesAquaculture Reports, 2023
A large number of red swamp crayfish (Procambarus clarkia) died at a crayfish breeding farm in Tianjin. Two dominant bacterial strains were isolated from the hepatopancreas of diseased crayfish and named PCG1 and PCG2, respectively.
Yufeng Su   +4 more
doaj   +1 more source

Acute toxicity study and phytochemical screening of Pterocarpus marsupium heartwood

open access: yesNational Journal of Physiology, Pharmacy and Pharmacology, 2022
Background: Conventionally, Ayurvedic herbs are being used to treat various diseases. These medicinal compounds have to be evaluated for their safety and presence of therapeutic compounds for the clinical application.
Narendar Koyagura   +2 more
doaj   +1 more source

Acute toxicity data of common agricultural insecticides to Japanese wild bees

open access: yesData in Brief, 2023
Although numerous ecotoxicological assessments of European honeybee (Apis mellifera L.) have been performed, Japanese wild bees are less well studied in this regard.
Yugo Seko   +5 more
doaj   +1 more source

Quantification of the Relative Virulence of White Spot Syndrome Virus (WSSV) in the Penaeid Shrimps Litopenaeus vannamei (Boone, 1931) and Farfantepenaeus duorarum (Burkenroad, 1939) by Quantitative Real Time PCR

open access: yesAnnals of Tropical Research, 2012
The relative virulence of the China isolate of white spot syndrome virus (WSSV-CN) in the penaeid shrimps Litopenaeus vannamei and Farfantepenaeus duorarum, was assessed by a comparison of 7-d median lethal dose (LD50), survival curve, and mean lethal ...
Rey J. dela Calzada, Jeffrey M. Lotz
doaj   +1 more source

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