Results 31 to 40 of about 56,603 (238)
Toxicity effects of water extracts of H olothuria atra Jaeger in mice
Asian Pacific Journal of Tropical Biomedicine, 2014 Objective: To determine lethal median dose (LD50) and histopathological toxicity of water extract of Holothuria atra (H. atra) in mice. Methods: The behavioral changes, mortality and histopathology examination on liver were assessed in mice 14 d after ...
Ridzwan Bin Hashim +5 more
doaj +1 more source
Toxicology Reports, 2021 Animal models are essential for evaluating the toxicity of chemical warfare nerve agents (CWNAs) to extrapolate to human risk and are necessary to evaluate the efficacy of medical countermeasures.
Lucille Lumley +10 more
doaj +1 more source
Effects of Piper nigrum L. Fruit Essential Oil Toxicity against Stable Fly (Diptera: Muscidae)
Plants, 2023 The efficacy of Piper nigrum L. fruit essential oil (EO) against Stomoxys calcitrans (stable fly), a blood-feeding fly distributed worldwide, was investigated.
Thekhawet Weluwanarak +4 more
doaj +1 more source
UMYU Journal of Microbiology Research, 2019 The continuous quest to annihilate the scourge of malaria parasites and the need for exploration of new drugs for the ever-endemic killer disease opens the way for continued research.
Liadi, Y. M. +3 more
doaj +1 more source
Median Lethality Dose of Xylopia aethiopica Fruit Ethanol Extract
Journal of Analytical Techniques and Research, 2019 The present study was designed to assess the median lethality dose of Xylopia aethiopica fruit ethanol extract (XAFEE) administration on sixteen albino rats. The animals were assigned to four groups (n=4). Each group was administered orally as single arithmetic doses of 1000 mg/kg b.w, 2000 mg/kg b.w, 3000 mg/kg b.w and 4000 mg/kg b.w respectively. The
Akinloye OA, Ayodele PF, Ore A
openaire +1 more source
Toxicity of microwave-assisted biosynthesized zinc nanoparticles in mice: a preliminary study
Artificial Cells, Nanomedicine, and Biotechnology, 2019 This study was designed to describe the oral acute and subacute toxicities and underlying toxicological mechanisms of biogenic Zn NPs in mice. The Zn NPs were prepared by a green microwave-assisted synthesis method in the presence of Lavandula vera leaf ...
Azad Salimi +5 more
doaj +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Pharmaceutics, 2021 The different effects on animals of the thrombolytic protease complex of the new producer S. strictum 203 were studied. The tests of acute toxicity, immunotoxicity and allergenicity should conclude that the studied proteolytic complex is safe for medical
Svetlana Alipkina +3 more
doaj +1 more source
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source