Results 11 to 20 of about 48,009 (234)
Selpercatinib, a RET kinase inhibitor, is an effective treatment for patients with medullary thyroid cancer with RET mutations. In this paper, we present the case of a 62-year-old man with ectopic Cushing’s syndrome due to medullary thyroid cancer who ...
Oskar Ragnarsson +2 more
doaj +1 more source
BackgroundSevere acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a novel coronavirus that has caused a worldwide pandemic. The majority of medullary thyroid cancers present as a thyroid nodule.
Livia Sira +7 more
doaj +1 more source
This study investigated postoperative complications after surgery for medullary thyroid carcinoma (MTC) in Europe. Hypoparathyroidism, recurrent laryngeal nerve palsy and bleeding requiring reoperation occurred in 170 (26·2 per cent), 62 (13·7 per cent) and 17 (2·6 per cent) patients respectively.
D.‐J. van Beek +18 more
wiley +1 more source
Abstract Background Medullary thyroid cancer (MTC) standard of care includes multikinase inhibitors (MKIs), which can exacerbate disease‐related diarrhea, primarily because of non‐RET kinase inhibition. We report diarrhea and other patient‐reported outcomes (PROs) with selpercatinib, a highly selective RET inhibitor, among patients with RET‐mutant MTC ...
Lori J. Wirth +10 more
wiley +1 more source
the aim of the stydy was to analyze the detectability of medullary thyroid metastases in patients at treatment and diagnostic stages, to investigate the applicability of serum calcitonin level as predictor of possible presence of medullary thyroid ...
Volodymyr Palamarchuk +6 more
doaj +1 more source
Anaplastic Thyroid Carcinoma Histologically Mimicking a Plasmacytoma. [PDF]
Anaplastic (undifferentiated) thyroid carcinoma (ATC) is a rare malignancy which may arise from transformation of a pre-existing differentiated carcinoma. We report the unique case where a lesion of thyroid origin presented with the histological features
Mo, Joshua H +4 more
core +1 more source
Breast metastasis from medullary thyroid carcinoma: a report of a case
Background Metastasis to the breast is rare. We herein report a patient with metastatic medullary thyroid carcinoma to the breast for whom measuring the calcitonin level was an important clue to the correct diagnosis.
Yoko Omi +6 more
doaj +1 more source
BACKGROUND: Medullary thyroid cancer, a tumor of the parafollicular C cells, accounts for approximately 10% of all thyroid malignancies. An estimated 75% of cases are sporadic, and the remaining 25% are familial. METHODS: The author reviews the clinical features and diagnostic tests for this entity, as well as the surgical treatment of recurrent or ...
Ramos Santillan V +3 more
europepmc +7 more sources
The goal in managing patients who have MTC is to detect and surgically remove disease at an early stage. Tumor marker-based biochemical screening and DNA-based genetic screening have created the opportunity for effective prophylactic surgery in patients at risk for hereditary MTC.
Y Nancy, You +3 more
openaire +4 more sources
Medullary thyroid cancer is rare, in 25 % of cases genetically determined (multiple endocrine neoplasia type 2), and should be treated by a specialized multidisciplinary team in the Cancer Center. In most cases, total thyroidectomy and at least central compartment lymph node dissection are required.
Barney Harrison, Bruno Carnaille
+5 more sources

