Results 11 to 20 of about 48,009 (234)

Successful Treatment with Selpercatinib for Ectopic Cushing’s Syndrome Due to Medullary Thyroid Cancer

open access: yesCurrent Oncology, 2022
Selpercatinib, a RET kinase inhibitor, is an effective treatment for patients with medullary thyroid cancer with RET mutations. In this paper, we present the case of a 62-year-old man with ectopic Cushing’s syndrome due to medullary thyroid cancer who ...
Oskar Ragnarsson   +2 more
doaj   +1 more source

Case Report: Medullary Thyroid Cancer Workup Initiated by Unexpectedly High Procalcitonin Level—Endocrine Training Saves Life in the COVID-19 Unit

open access: yesFrontiers in Endocrinology, 2021
BackgroundSevere acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a novel coronavirus that has caused a worldwide pandemic. The majority of medullary thyroid cancers present as a thyroid nodule.
Livia Sira   +7 more
doaj   +1 more source

Complications after medullary thyroid carcinoma surgery: multicentre study of the SQRTPA and EUROCRINE® databases

open access: yesBJS (British Journal of Surgery), EarlyView., 2020
This study investigated postoperative complications after surgery for medullary thyroid carcinoma (MTC) in Europe. Hypoparathyroidism, recurrent laryngeal nerve palsy and bleeding requiring reoperation occurred in 170 (26·2 per cent), 62 (13·7 per cent) and 17 (2·6 per cent) patients respectively.
D.‐J. van Beek   +18 more
wiley   +1 more source

Patient‐Reported Outcomes with Selpercatinib Treatment Among Patients with RET‐Mutant Medullary Thyroid Cancer in the Phase I/II LIBRETTO‐001 Trial

open access: yesThe Oncologist, EarlyView., 2021
Abstract Background Medullary thyroid cancer (MTC) standard of care includes multikinase inhibitors (MKIs), which can exacerbate disease‐related diarrhea, primarily because of non‐RET kinase inhibition. We report diarrhea and other patient‐reported outcomes (PROs) with selpercatinib, a highly selective RET inhibitor, among patients with RET‐mutant MTC ...
Lori J. Wirth   +10 more
wiley   +1 more source

The role of calcitonin in the preoperative stage as the predictor of medullary thyroid cancer metastases

open access: yesUkrainian Scientific Medical Youth Journal, 2021
the aim of the stydy was to analyze the detectability of medullary thyroid metastases in patients at treatment and diagnostic stages, to investigate the applicability of serum calcitonin level as predictor of possible presence of medullary thyroid ...
Volodymyr Palamarchuk   +6 more
doaj   +1 more source

Anaplastic Thyroid Carcinoma Histologically Mimicking a Plasmacytoma. [PDF]

open access: yes, 2020
Anaplastic (undifferentiated) thyroid carcinoma (ATC) is a rare malignancy which may arise from transformation of a pre-existing differentiated carcinoma. We report the unique case where a lesion of thyroid origin presented with the histological features
Mo, Joshua H   +4 more
core   +1 more source

Breast metastasis from medullary thyroid carcinoma: a report of a case

open access: yesSurgical Case Reports, 2021
Background Metastasis to the breast is rare. We herein report a patient with metastatic medullary thyroid carcinoma to the breast for whom measuring the calcitonin level was an important clue to the correct diagnosis.
Yoko Omi   +6 more
doaj   +1 more source

Medullary Thyroid Cancer

open access: yesCancer control : journal of the Moffitt Cancer Center
BACKGROUND: Medullary thyroid cancer, a tumor of the parafollicular C cells, accounts for approximately 10% of all thyroid malignancies. An estimated 75% of cases are sporadic, and the remaining 25% are familial. METHODS: The author reviews the clinical features and diagnostic tests for this entity, as well as the surgical treatment of recurrent or ...
Ramos Santillan V   +3 more
europepmc   +7 more sources

Medullary Thyroid Cancer

open access: yesSurgical Oncology Clinics of North America, 2006
The goal in managing patients who have MTC is to detect and surgically remove disease at an early stage. Tumor marker-based biochemical screening and DNA-based genetic screening have created the opportunity for effective prophylactic surgery in patients at risk for hereditary MTC.
Y Nancy, You   +3 more
openaire   +4 more sources

Medullary Thyroid Cancer

open access: yesOncology Times, 2013
Medullary thyroid cancer is rare, in 25 % of cases genetically determined (multiple endocrine neoplasia type 2), and should be treated by a specialized multidisciplinary team in the Cancer Center. In most cases, total thyroidectomy and at least central compartment lymph node dissection are required.
Barney Harrison, Bruno Carnaille
  +5 more sources

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