Results 21 to 30 of about 48,009 (234)

IGF-I influences everolimus activity in medullary thyroid carcinoma [PDF]

, 2015
Context: Medullary thyroid carcinoma (MTC) is a rare tumor originating from thyroid parafollicular C cells. It has been previously demonstrated that insulin-like growth factor I (IGF-I) protects MTC from the effects of antiproliferative drugs. Everolimus,
degli Uberti, Ettore C., Di Pasquale, Carmelina, Gagliano, Teresa, GENTILIN, ERICA, MERANTE BOSCHIN, ISABELLA, Pelizzo, Mariarosa, Rossi, Martina, Rossi, Roberta, Tagliati, Federico, Zatelli, Maria Chiara   +9 more
core   +1 more source

Combination of medullary thyroid cancer and renal cell carcinoma in one patient

Клиническая и экспериментальная тиреоидология, 2018
Patients who received treatment for the first malignant neoplasm remain in the group at increased risk of developing a second primary tumor throughout their later life.
Yuliya A. Dolinskaya, Sergey P. Shevchenko, Vladimir N. Maksimov, Elena N. Voropaeva, Oksana D. Rymar   +4 more
doaj   +1 more source

Susceptibility Genes and Chromosomal Regions Associated With Non-Syndromic Familial Non-Medullary Thyroid Carcinoma: Some Pathogenetic and Diagnostic Keys

Frontiers in Endocrinology, 2022
Thyroid cancer is the malignant tumor that is increasing most rapidly in the world, mainly at the expense of sporadic papillary thyroid carcinoma. The somatic alterations involved in the pathogenesis of sporadic follicular cell derived tumors are well ...
María Sánchez-Ares, Soledad Cameselle-García, Ihab Abdulkader-Nallib, Ihab Abdulkader-Nallib, Gemma Rodríguez-Carnero, Carolina Beiras-Sarasquete, José Antonio Puñal-Rodríguez, José Antonio Puñal-Rodríguez, José Manuel Cameselle-Teijeiro, José Manuel Cameselle-Teijeiro   +9 more
doaj   +1 more source

Elastographic presentation of medullary thyroid carcinoma [PDF]

, 2013
Aim of the study was to evaluate the elastographic appearance of medullary thyroid carcinoma (MTC) by a retrospective evaluation of 18 nodules histologically proven as MTC. Free-hand qualitative elastography was performed using Hitachi Logos EUB 7500.
Amendola, Stefano, Andrioli, Massimiliano, Fukunari, Nobuhiro, Mirella, Moro, Persani, Luca, Trimboli, Pierpaolo, Valabrega, Stefano   +6 more
core   +1 more source

Genetic susceptibility to hereditary non-medullary thyroid cancer

Hereditary Cancer in Clinical Practice, 2022
Non-medullary thyroid cancer (NMTC) is the most common type of thyroid cancer. With the increasing incidence of NMTC in recent years, the familial form of the disease has also become more common than previously reported, accounting for 5–15% of NMTC ...
Tina Kamani, Parsa Charkhchi, Afshan Zahedi, Mohammad R. Akbari   +3 more
doaj   +1 more source

Tyrosine kinase inhibitors for the therapy of anaplastic thyroid cancer [PDF]

, 2015
Anaplastic thyroid cancer (ATC) is often incurable so new therapeutic approaches are needed. Tyrosine kinases inhibitors (such as imanitib, sunitinib or sorafenib) are under evaluation for the treatment of ATC.
Bond JA, Cohen EE, Dowlati A, Goulart B, Grande E, Hayashi N, Ibrahim N, Klopper JP, Mahlknecht U, Ohta K, Ruggeri RM, Sherman SI   +11 more
core   +1 more source

Pediatric thyroid disease: when is surgery necessary, and who should be operating on our children? [PDF]

, 2013
Surgical diseases of the thyroid in the pediatric population represent a diverse set of both benign and malignant conditions. Overall, incidence is rare.
Breuer, Christopher, Solomon, Daniel, Sosa, Julie Ann, Tuggle, Charles   +3 more
core   +1 more source

Educational Case: Endocrine Neoplasm

Academic Pathology, 2018
Medullary thyroid cancer is a rare neuroendocrine tumor that arises the neural crest-derived parafollicular C cells and accounts for approximately 5% to 10% of thyroid cancers worldwide.
Sheila Segura MD, Gloria Ramos-Rivera MD, Mark Suhrland MD   +2 more
doaj   +1 more source

Medullary thyroid cancer: a little history

Mìžnarodnij Endokrinologìčnij Žurnal, 2022
The literature review presents the history on the deve­lopment of modern ideas about medullary thyroid cancer, which is a little more than fifty years.
S.Y. Rybakov
doaj   +1 more source

Identification of BCL2L11 as a Candidate Gene for Hereditary Predisposition to Non-Medullary Thyroid Cancer Using Familial Whole-Exome-Sequencing. [PDF]

Clin Genet
Whole‐exome sequencing of five families with non‐medullary thyroid cancer revealed three candidate genes. Functional analyses confirmed BCL2L11 as a strong candidate gene for hereditary predisposition to non‐medullary thyroid cancer. ABSTRACT Familial non‐medullary thyroid cancer, defined as two or more affected first‐degree relatives, accounts for 3 ...
Abbasoglu D, Lepage M, Sonnier N, Viala S, Uhrhammer N, Ponelle-Chachuat F, Cayre A, Privat M, Cavaillé M, Bidet Y.   +9 more
europepmc   +2 more sources