Results 31 to 40 of about 48,009 (234)

RET mutation and increased angiogenesis in medullary thyroid carcinomas [PDF]

, 2016
Advanced medullary thyroid cancers (MTCs) are now being treated with drugs that inhibit receptor tyrosine kinases, many of which involved in angiogenesis.
Acquaviva, Giorgia, Boichard, Amélie, Casadei, Gian Piero, Checquolo, Saula, Colato, Chiara, de Biase, Dario, Durante, Cosimo, Ferdeghini, Marco, Filetti, Sebastiano, Pecce, Valeria, Rhoden, Kerry, Rosignolo, Francesca, Russo, Diego, Sponziello, Marialuisa, Tallini, Giovanni, Verrienti, Antonella, Visani, Michela   +16 more
core   +1 more source

Medullary Thyroid Cancer: An Introduction [PDF]

Current Oncology, 2019
Medullary thyroid cancer (mtc) is a rare cancer, making up perhaps only a few percent of all thyroid cancers […]
openaire   +2 more sources

External radiotherapy of thyroid cancer [PDF]

, 2001
Differentiated thyroid cancer comprises papillary, mixed papillary-follicular and follicular adenocarcinomas. They are mostly hormone-sensitive and respond to thyroid-stimulating hormone (TSH) suppression. The standard treatment is total thyroidectomy. I-
Dühmke, Eckhart, Pollinger, B.
core   +1 more source

Preventive Transoral Endoscopic Thyroidectomy by Vestibular Approach in 6-Year-Old Patient with the High-Risk RET C634R Germline Mutation

Case Reports in Oncology, 2023
Aggressiveness and age of manifestation of medullary thyroid cancer depend on the risk level of germline RET mutations. For high-risk mutations, preventive thyroidectomy is recommended at young age.
Yury Panaseykin, Vyacheslav Polkin, Nataliya Severskaya, Pavel Isaev, Aleksey Iliyn, Alisa Plugar, Ekaterina Kupriyanova, Sergey Ivanov, Andrey Kaprin   +8 more
doaj   +1 more source

A constitutive active MAPK/ERK pathway due to BRAFV600E positively regulates AHR pathway in PTC [PDF]

, 2015
The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor mediating the toxicity and tumor-promoting properties of dioxin. AHR has been reported to be overexpressed and constitutively active in a variety of solid tumors, but few data
Barollo, Susi, Bertazza, Loris, Bisognin, Andrea, Bortoluzzi, Stefania, Boscaro, Marco, Ceccato, Filippo, Ciato, Denis, Galuppini, Francesca, Guzzardo, Vincenza, Jaffrain Rea, Marie Lise, Mian, Caterina, Occhi, Gianluca, Pennelli, Gianmaria, Regazzo, Daniela, Scaroni, Carla, Vianello, Federica, WATUTANTRIGE FERNANDO, Sara   +16 more
core   +4 more sources

A Benign Medullary Thyroid Cancer [PDF]

Cureus, 2022
Metastatic dissemination occurs in up to 90% of patients with medullary thyroid cancer (MTC) greater than 4 cm in diameter, and elevated calcitonin levels of more than 500 pg/ml preoperatively have been shown to predict the failure to achieve biochemical remission. Herein, we present a patient with a large tumor and extremely elevated calcitonin level,
Pishdad, Reza, Vahidi Rad, Mona, Cespedes, Lissette   +2 more
openaire   +2 more sources

Current perspectives on the management of patients with advanced RET-driven thyroid cancer in Europe

Frontiers in Oncology, 2023
The incidence of thyroid cancer is increasing worldwide with the disease burden in Europe second only to that in Asia. In the last several decades, molecular pathways central to the pathogenesis of thyroid cancer have revealed a spectrum of targetable ...
Rossella Elisei, Enrique Grande, Michael C. Kreissl, Sophie Leboulleux, Tarun Puri, Nicolas Fasnacht, Jaume Capdevila   +6 more
doaj   +1 more source

Unmodifiable variables related to thyroid cancer incidence [PDF]

, 2018
The incidence of thyroid cancer is significantly different between male and female patients. Thyroid cancer is also the only form of cancer where age can be considered a staging variable.
Alecu, Lucian, Hainarosie, Razvan, Jecan, Radu C., Nitipir, Cornelia, Orlov, Cristina, Pituru, Silviu, Slavu, Iulian, Stanculeanu, Dana L., Stoian, Anca P., Tulin, Adrian, Tulin, Raluca   +10 more
core   +2 more sources

Simultaneous Medullary and Papillary Thyroid Carcinoma with Lymph Node Metastasis in the Same Patient: Case Report and Review of the Literature

Asian Journal of Surgery, 2005
We report a rare case of simultaneous medullary thyroid carcinoma on the left thyroid lobe with lymph node metastasis and papillary thyroid cancer on the right thyroid lobe.
Nidal Younes
doaj   +1 more source

Is thyroid nodule location associated with malignancy risk? [PDF]

, 2019
PURPOSE: Nodules located in the upper pole of the thyroid may carry a greater risk for malignancy than those in the lower pole. We conducted a study to analyze the risk of malignancy of nodules depending on location.
Biffoni, Marco, Ciotti, Laura, Durante, Cosimo, Falcone, Rosa, Giacomelli, Laura, Grani, Giorgio, Lamartina, Livia, Lomonaco, Cristiano, Maranghi, Marianna, Ramundo, Valeria   +9 more
core   +1 more source