Results 51 to 60 of about 8,365 (219)

An experimental investigation of fairness and reciprocal behavior in a triangular principal-multiagent relationship [PDF]

, 2001
Issues of fairness in hierarchies have been mostly investigated - both theoretically and experimentally - within dyadic principle-agent relationships.
Rossi, Alessandro, Warglien, Massimo
core  

Distribution of MEFV gene mutations and R202Q polymorphism in the Serbian population and their influence on oxidative stress and clinical manifestations of inflammation [PDF]

, 2016
BACKGROUND: The Mediterranean fever (MEFV) gene codes for protein pyrin, one of the regulators of inflammasome activity in innate immune cells. Mutations in this gene are considered the primary cause of Familial Mediterranean fever, but are also found in
Andrej Veljković, Dragana Lazarević, Dušica Pavlović, Gordana Kocić, Jelena Milenković, Jelena Vojinović, Maja Milojković, Maruša Debeljak, Nataša Toplak, Tadej Avčin, Tatjana Jevtović-Stoimenov, Vladmila Bojanić   +11 more
core   +1 more source

Familial Mediterranean fever : MEFV gene mutations and treatment

Japanese Journal of Clinical Immunology, 2007
Familial Mediterranean fever (FMF) is an autosomal recessive disease which predominantly affects certain ethnic groups mainly Sephardic Jews, Turks, Arabs and Armenians. FMF has been rarely reported in Japan. Characteristic symptoms include self-limited recurrent attacks of fever with serositis such as peritonitis, pleuritis, and arthritis.
Megumu, Saito, Ryuta, Nishikomori, Naotomo, Kambe   +2 more
openaire   +3 more sources

TNF Inhibitor Therapy in Corticosteroid‐Resistant or ‐Dependent Pediatric Neutrophilic Dermatosis

Pediatric Dermatology, EarlyView.
ABSTRACT Neutrophilic dermatoses are rare in children. Systemic corticosteroids are the first‐line treatment, but guidelines for second‐line therapies are lacking. We report five cases of children with systemic steroid‐resistant/dependent neutrophilic dermatoses, successfully treated with tumor necrosis factor inhibitors.
Laure Chêne, Thomas Hubiche, Jean‐Marie De Guillebon, Maella Severino‐Freire, Emmanuelle Bourrat, Sébastien Barbarot, Alice Phan, Christine Chiaverini   +7 more
wiley   +1 more source

An Alternative Perspective to the FMF Clinic: MCP-1 (A-2518G) and CCR2 (G190A) Polymorphisms and MCP1 Expression

Journal of Contemporary Medicine, 2022
Background: Familial Mediterranean Fever (FMF) is an autoinflammatory disease and may express as various clinical findings. Chemokines are crucial elements of the inflammatory process.
Nadir Koçak, Şenol Çitli
doaj   +1 more source

Autoimmune-autoinflammatory rheumatoid arthritis overlaps: a rare but potentially important subgroup of diseases [PDF]

, 2017
At the population level, rheumatoid arthritis (RA) is generally viewed as autoimmune in nature with a small subgroup of cases having a palindromic form or systemic autoinflammatory disorder (SAID) phenotype.
Barcenas-Morales, G, Doffinger, R, Emery, P, McGonagle, D, Mistry, A, Savic, S, Wilson, AG   +6 more
core   +1 more source

The effects of epigenetic regulation on phenotypic expressivity in Turkish patients with familial Mediterranean fever

Indian Journal of Rheumatology, 2019
Introduction: In this study, we aimed to characterize the effect of methylation on clinical diversity and gene expression levels in familial Mediterranean fever.
Eser Dogan, Semra Gursoy, Giray Bozkaya, Secil Arslansoyu Camlar, Ozge Aksel Kilicarslan, Alper Soylu, Ayfer Ulgenalp, Salih Kavukcu, Ozlem Giray Bozkaya   +8 more
doaj   +1 more source

Obesity‐Associated TRIM15 Promotes the Proliferation of Esophageal Adenocarcinoma Through the YY2/FOXRED1 Axis

Advanced Science, Volume 13, Issue 4, 19 January 2026.
The study identifies TRIM15 as a key driver in the development of obesity‐associated esophageal adenocarcinoma (EAC). Mechanistically, TRIM15 degrades YY2 through the proteasome pathway, suppressing FOXRED1 transcription and ultimately accelerating tumor proliferation.
Haohui Wang, Chong Yang, Dayuan Luo, Pingting Liu, Zhen Zeng, Weilin Peng, Dongzi Peng, Hao Su, Xiaoxiong Xiao, Haiqin Wang, Xin Jin   +10 more
wiley   +1 more source

MEFV Gene Mutation Analysis in Children with Immunoglobulin A Vasculitis and Its Effects on Clinical Manifestations: A Big Series from a Tertiary Center

Haseki Tıp Bülteni
Aim: Immunoglobulin A vasculitis (IgAV) is the most common vasculitis of childhood, but its pathogenesis is largely unknown, despite evidence pointing to various environmental and genetic factors. We investigated the frequency of MEFV gene mutations that
Sema Yildirim, Zeynep Karakaya, Ozlem Ozcay, Muferet Erguven   +3 more
doaj   +1 more source

Ageing exacerbates the adverse effects of respiratory muscle fatigue on vascular function, locomotor muscle fatigue and exercise performance in males

Experimental Physiology, Volume 111, Issue 1, Page 283-299, 1 January 2026.
Abstract This study investigated the effect of respiratory muscle fatigue on cardiovascular function, locomotor muscle fatigue and exercise performance in young and master athletes, a model of successful ageing. Ten young male (YA, 27.4 ± 4.4 years) and 11 male master endurance athletes (MA, 65.0 ± 5.1 years) performed, on separate days, two constant ...
Valentin Mons, Colin Lavigne, Olivier Meste, Benjamin Mauroy, Gregory M. Blain   +4 more
wiley   +1 more source