Results 71 to 80 of about 34,194 (287)
Inherited thrombocytopenias—recent advances in clinical and molecular aspects
Platelets, 2017 Since the beginning of the century, our knowledge of inherited thrombocytopenias greatly advanced, and we presently know 30 forms with well-defined genetic defects.
Carlo L. Balduini +2 more
doaj +1 more source
Megakaryocytes in the Pulmonary Circulation [PDF]
Blood, 1963 Abstract The streptolysin 0 hemolysis method for isolation of cancer cells in the blood was employed for direct observations of the incidence and some characteristics of circulating megakaryocytes. In a series of 168 patients, circulating megakaryocytes were found in 77 per cent of the blood samples.
T M, SCHEININ, A P, KOIVUNIEMI
openaire +2 more sources
Repeated Exposure to a Hair Bleaching Mixture Alters cGAS–STING Pathway Transcripts in Mice
Journal of Applied Toxicology, EarlyView.ABSTRACT Hair bleaching products commonly contain ammonia and hydrogen peroxide, chemicals capable of generating reactive oxygen species (ROS). However, their effects on innate immune signaling pathways associated with DNA damage remain poorly understood.
Leticia Rodrigues Sampaio +2 more
wiley +1 more source
Role of Megakaryocytes in Breast Cancer Metastasis to Bone
, 2017 Little is known about how megakaryocytes may affect metastasis beyond serving as a source of platelets. In this study, we explored the functional implications of megakaryocyte accumulation in the femurs of mice after injection of metastatic or non ...
Donna M. Sosnoski +6 more
core +1 more source
Journal of Clinical Laboratory Analysis, EarlyView.ABSTRACT Background T‐cell lymphoblastic lymphoma (T‐LBL) and T‐cell acute lymphoblastic leukemia (T‐ALL) are considered a single biological entity, distinguished primarily by the extent of bone marrow infiltration. This distinction becomes diagnostically challenging in patients with borderline marrow blast counts and predominantly extramedullary ...
Chen Glait‐Santar +3 more
wiley +1 more source
Rapid S-nitrosothiol metabolism by platelets and megakaryocytes
, 2003 RSNOs (S-nitrosothiols) regulate platelet and megakaryocyte function, and may act in vivo as a nitric oxide reservoir. There is a discrepancy between the spontaneous rate of NO release from different RSNO compounds and their pharmacological effects ...
Shah, C.M. +3 more
core
Primary Megakaryocytes Reveal a Role for Transcription Factor Nf-E2 in Integrin αiibβ3 Signaling [PDF]
, 1999 Platelet integrin αIIbβ3 responds to intracellular signals by binding fibrinogen and triggering cytoskeletal reorganization, but the mechanisms of αIIbβ3 signaling remain poorly understood.
Sanford Shattil +19 more
core +1 more source
Biological Specificities of Fetal Anemia Induced by Parvovirus B19 Infection
Prenatal Diagnosis, EarlyView.ABSTRACT Objective To describe the biological fetal parameters in cases of severe anemia induced by parvovirus B19 (B19V) infection. Method A retrospective single center study was conducted including cases of fetal anemia due to B19V receiving in utero transfusion (IUT) from January 2011 to May 2024.
Anaïs Dugas +9 more
wiley +1 more source
Characterization of adhesive interactions between human endothelial cells and megakaryocytes [PDF]
, 1993 Cell-cell adhesion is essential for many immunological functions and is believed to be important in the regulation of hematopoiesis. Adhesive interactions between human endothelial cells and megakaryocytes were characterized in vitro using the CMK ...
Avraham, H +10 more
core +1 more source