Effect of Local Administration of Meglumine Antimoniate and Polyhexamethylene Biguanide Alone or in Combination with a Toll-like Receptor 4 Agonist for the Treatment of Papular Dermatitis due to Leishmania infantum in Dogs [PDF]
Pathogens, 2023 Papular dermatitis is a cutaneous manifestation of canine Leishmania infantum infection associated with mild disease. Although it is a typical presentation, nowadays, there is still no established treatment.
Icíar Martínez-Flórez +10 more
doaj +2 more sources
Comparison of meglumine antimoniate versus miltefosine in the treatment of new world cutaneous leishmaniasis: a systematic review and meta-analysis [PDF]
Anais Brasileiros de DermatologiaBackground Cutaneous leishmaniasis (CL) affects up to 1.2 million people annually, mainly in resource-limited regions. Meglumine antimoniate, the standard treatment, is limited by systemic toxicity, injectable administration, and increasing resistance ...
Ana Carolina Putini Vieira +2 more
doaj +3 more sources
Successful treatment of meglumine antimoniate in patient with cutaneous leishmaniasis with end-stage renal failure undergoing hemodialysis: a case report [PDF]
Journal of Medical Case ReportsBackground Cutaneous leishmaniasis is the most common form of leishmaniasis. Meglumine antimoniate is the first line of available treatment in developing countries. There is limited research on the renal effects of antimonial compounds. Case presentation
Hazem Arab +4 more
doaj +2 more sources
New onset of sinoatrial block in a young patient treated with systemic meglumine antimoniate [PDF]
Clinical Case Reports, 2021 The sinoatrial block is a new side effect of meglumine antimoniate. Prompt interruption of the drug results in the normalization of electrographic changes and prevents sudden cardiac arrest.
Najla Daadaa +6 more
doaj +2 more sources
Comparison of Intralesional Sodium Stibogluconate versus Intralesional Meglumine Antimoniate for the Treatment of Leishmania major Cutaneous Leishmaniasis [PDF]
Acta Dermato-VenereologicaIsrael is endemic for Old-World cutaneous leishmaniasis. The most common species is Leishmania major. However, the available treatment options are limited.
Michal Solomon +6 more
doaj +2 more sources
Is pancreatitis associated with meglumine antimoniate treatment for canine leishmaniosis? A multicentric prospective study [PDF]
Parasites & VectorsBackground Meglumine antimoniate is used to treat canine leishmaniosis. In humans, it has been associated with pancreatitis. Although a few case reports have described acute pancreatitis secondary to antimonial treatment in dogs, some studies have ...
Clàudia Viñeta +6 more
doaj +2 more sources
Effects of meglumine antimoniate and allopurinol treatment on the fecal microbiome profile in dogs with leishmaniosis [PDF]
Animal MicrobiomeBackground The combination of meglumine antimoniate and allopurinol is considered one of the most effective treatments for canine leishmaniosis caused by Leishmania infantum.
Joan Martí-Carreras +8 more
doaj +2 more sources
A Novel Strategy for Enhance Potentiation of Meglumine antimoniate against Leishmania major In Vitro [PDF]
Iranian Journal of Parasitology, 2019 Background: We aimed to design a different method of drug delivery for increased transfer of the choice drug (meglumine antimoniate) within the host cells.
Farzaneh MIRZAEI +4 more
doaj +2 more sources
Pharmacokinetics of neutron-irradiated meglumine antimoniate in Leishmania amazonensis-infected BALB/c mice [PDF]
Journal of Venomous Animals and Toxins including Tropical Diseases, 2019 Background: Cutaneous leishmaniasis (CL) is a parasitic disease caused by the protozoan Leishmania spp. Pentavalent antimonial agents have been used as an effective therapy, despite their side effects and resistant cases.
Samanta Etel Treiger Borborema +3 more
doaj +2 more sources
Pakistan Armed Forces Medical Journal, 2021 Objective: To identify electrocardiographic changes associated with parenteral meglumine antimoniate and to estimate frequency of these changes. Study Design: Prospective observational study.
Moizza Tahir +3 more
doaj +1 more source