Results 41 to 50 of about 4,754 (217)

Comparison of Meglumine Antimoniate and Miltefosine in Cutaneous Leishmaniasis

open access: yesJournal of the College of Physicians and Surgeons Pakistan, 2023
To compare the efficacy and safety of meglumine antimoniate and miltefosine in the treatment of cutaneous leishmaniasis in Pakistan.Randomised-controlled trial. Place and Duration of the Study: Department of Dermatology, Combined Military Hospital, Lahore and Peshawar, from January to December 2021.Smear positive and/or skin biopsy-confirmed cases of ...
Atiya, Rahman   +6 more
openaire   +2 more sources

Management of trypanosomiasis and leishmaniasis [PDF]

open access: yes, 2012
<p>Background: The current treatments for human African trypanosomiasis (HAT), Chagas disease and leishmaniasis (collectively referred to as the kinetoplastid diseases) are far from ideal but, for some, there has been significant recent progress ...
Alsford   +39 more
core   +2 more sources

Comparison of Intralesional Meglumine Antimoniate Plus Oral Allopurinol with Intralesional Meglumine Antimoniate Alone for the Treatment of Cutaneous Leishmaniasis- A Prospective Study

open access: yesLife and Science
Objective: To evaluate the efficacy of the combination of oral allopurinol plus intralesional meglumine for the treatment of Cutaneous Leishmaniasis. Study Design: A prospective study.
Nida Qayyum   +5 more
doaj   +1 more source

Ex vivo host and parasite response to antileishmanial drugs and immunomodulators. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2015
BACKGROUND:Therapeutic response in infectious disease involves host as well as microbial determinants. Because the immune and inflammatory response to Leishmania (Viannia) species defines the outcome of infection and efficacy of treatment ...
Laura Gonzalez-Fajardo   +3 more
doaj   +1 more source

A 6 day course of liposomal amphotericin B in the treatment of infantile visceral leishmaniasis: the Italian experience [PDF]

open access: yes, 2004
OBJECTIVES: To evaluate in a retrospective analysis the efficacy and safety of a 6 day course of liposomal amphotericin B (L-AmB) in infantile cases of Mediterranean visceral leishmaniasis (VL) diagnosed over a 10 year period in Italy.
Aiassa, C   +14 more
core   +2 more sources

Intralesional treatment with meglumine antimoniate in three patients with New World cutaneous leishmaniasis and large periarticular lesions with comorbidities

open access: yesRevista da Sociedade Brasileira de Medicina Tropical
Although New World cutaneous leishmaniasis is not itself a life-threatening disease, its treatment with systemic antimonials can cause toxicity that can be dangerous to some patients.
Maria Inês Fernandes Pimentel   +7 more
doaj   +1 more source

Pupal surveys for Aedes aegypti surveillance and potential targeted control in residential areas of Mérida, México.

open access: yes, 2008
A mosquito larval-pupal survey was conducted in 1,160 households of the Mexican city of Mérida during the rainy season of 2003 to determine their differential productivity for Aedes aegypti.
Che-Medoza, Azael   +6 more
core   +1 more source

Antileishmanial and cytotoxic effects of essential oil and methanolic extract of Myrtus communis L. [PDF]

open access: yes, 2015
: Plants used for traditional medicine contain a wide range of substances that can be used to treat various diseases such as infectious diseases. The present study was designed to evaluate the antileishmanial effects of the essential oil and methanolic
Ezzatkhah, Fatemeh.   +4 more
core   +1 more source

Antileishmanial Activity of 2-Methoxy-4H-spiro-[naphthalene-1,2′-oxiran]-4-one (Epoxymethoxy-lawsone): A Promising New Drug Candidate for Leishmaniasis Treatment

open access: yesMolecules, 2018
Epoxymethoxylawsone is a naphthoquinone derivative promising as drug candidate for the treatment of leishmaniases. In the present work the effectiveness of epoxymethoxylawsone, and meglumine antimoniate on Leishmania (Leishmania) amazonensis parasites ...
Luiz Filipe Gonçalves Oliveira   +10 more
doaj   +1 more source

Comparison of in vitro Resistance of Wild Leishmania İsolates, Which are Resistant to Pentavalent Antimonial Compounds, Against Drugs Used in the Treatment of Leishmaniasis

open access: yesTürkiye Parazitoloji Dergisi, 2020
Objective:Meglumine antimoniate (Glucantime®) and Sodium stibogluconate (Pentostam®) are used for the treatment of cutaneous leismaniasis in Turkey. There is a reported resistance to these drugs in recent years.
Ahmet Özbilgin   +4 more
doaj   +1 more source

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