Risk factors for in-hospital mortality of visceral leishmaniasis patients in eastern Uganda. [PDF]
, 2009 OBJECTIVE: To identify risk factors for in-hospital mortality in patients treated for visceral leishmaniasis (VL) in Uganda. METHODS: Retrospective analysis of VL patients' clinical data collected for project monitoring by Médecins Sans Frontières in ...
Bern +20 more
core +3 more sources
Cost-effectiveness study of therapeutic approaches for mucosal leishmaniasis [PDF]
Cadernos de Saúde Pública: This study aimed to estimate the cost-effectiveness of four therapeutic approaches available for mucosal leishmaniasis in Brazil: miltefosine, meglumine antimoniate, combined with and without pentoxifylline, and liposomal amphotericin B.
Janaína de Pina Carvalho +5 more
doaj +1 more source
Efficacy of Thermotherapy to Treat Cutaneous Leishmaniasis Caused by Leishmania tropica in Kabul, Afghanistan: A Randomized, Controlled Trial [PDF]
, 2005 BACKGROUND: Pentavalent antimony is the agent recommended for treatment of cutaneous leishmaniasis (CL). Its use is problematic, because it is expensive and because of the potential for drug-associated adverse effects during a lengthy and painful ...
Aram H +23 more
core +1 more source
Chitosan-titanium dioxide-glucantime nanoassemblies effects on promastigote and amastigote of Leishmania major [PDF]
, 2018 The purpose of the present study was to design nanoassemblies of chitosan-titanium dioxide (TiO2) nanoparticles (NPs) loaded with glucantime for using their synergistic effects and enhancing the toxic effects of glucantime on Leishmania parasites.
Arbabi, B. +4 more
core +1 more source
Pakistan Armed Forces Medical Journal, 2021 Objective: To compare the efficacy of oral chloroquine with systemic meglumine antimoniate in treatment of cutaneous leishmaniasis. Study Design: Open-label comparative prospective study.
Muhammad Farooq +3 more
doaj +1 more source
In vitro and in vivo antileishmanial activities of Pistacia vera essential oil [PDF]
, 2016 This study aims to evaluate the in vitro and in vivo antileishmanial activities of Pistacia vera essential oil and compare their efficacy with a reference drug, meglumine antimoniate (Glucantime®).
Ezatpour, Behrouz. +5 more
core +1 more source
Journal of Vector Borne Diseases, 2020 Background & objectives: Pentavalent antimonials are the standard treatment for cutaneous leishmaniasis (CL), however, treatment failures are frequent. Nimodipine, a calcium channel blocker is known to show promising antiprotozoal effects.
Reza Azadi +6 more
doaj +1 more source
In vitro and in vivo antileishmanial effects of Pistacia khinjuk against Leishmania tropica and Leishmania major [PDF]
, 2015 The present study aims to evaluate the in vitro and in vivo antileishmanial activities of Pistacia khinjuk Stocks (Anacardiaceae) alcoholic extract and to compare its efficacy with a reference drug, meglumine antimoniate (MA, Glucantime), against ...
Azadpour, Mojgan. +4 more
core +3 more sources
Characterization of the Antimonial Antileishmanial Agent Meglumine Antimonate (Glucantime) [PDF]
Antimicrobial Agents and Chemotherapy, 1998 ABSTRACT Meglumine antimonate (Glucantime), a drug of choice for the treatment of leishmaniasis, is produced by the reaction of pentavalent antimony with N -methyl- d -glucamine, a carbohydrate derivative.
W L, Roberts, W J, McMurray, P M, Rainey
openaire +2 more sources
Preparatory Work for the Future Development of Scientific Opinions on Animal Health [PDF]
, 2015 This final report summarizes the results of two reviews and a scoping study related to Canine leishmaniosis (CanL). Three objectives were addressed in this project.
Dzikamunhenga, Rungano +6 more
core +3 more sources