Results 11 to 20 of about 2,191 (109)
Pakistan Armed Forces Medical Journal, 2021 Objective: To identify electrocardiographic changes associated with parenteral meglumine antimoniate and to estimate frequency of these changes. Study Design: Prospective observational study.
Moizza Tahir +3 more
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Efficacy of Spironolactone Treatment in Murine Models of Cutaneous and Visceral Leishmaniasis
Frontiers in Pharmacology, 2021 Translational studies involving the reuse and association of drugs are approaches that can result in higher success rates in the discovery and development of drugs for serious public health problems, including leishmaniasis.
Valter Viana Andrade-Neto +7 more
doaj +1 more source
Embryonic toxico-pathological effects of meglumine antimoniate using a chick embryo model. [PDF]
PLoS ONE, 2018 Leishmaniasis is one of the diverse and neglected tropical diseases. Embryo-toxicity of drugs has always been a major concern. Chick embryo is a preclinical model relevant in the assessment of adverse effects of drugs.
Ahmad Khosravi +7 more
doaj +1 more source
Revista da Sociedade Brasileira de Medicina Tropical, 2019 Cutaneous leishmaniasis (CL) is a high-morbidity, vector-borne disease endemic to Colombia. Unlike conventional systemic antileishmanial therapy, intralesional meglumine antimoniate administration has fewer adverse effects and can be as effective and ...
Margarita Arboleda +3 more
doaj +1 more source
Novel methods for the encapsulation of meglumine antimoniate into liposomes
Brazilian Journal of Medical and Biological Research, 2000 The antimonial drug, meglumine antimoniate, was successfully encapsulated in dehydration-rehydration vesicles and in freeze-dried empty liposomes (FDELs).
F. Frézard +3 more
doaj +1 more source
Microorganisms, 2021 Cutaneous leishmaniasis (CL) caused by Leishmania (Leishmania) infantum is endemic in the Mediterranean basin. Here we report an autochthonous case of CL in a patient living in central Italy with an unsatisfactory response to treatment with intralesional
Aurora Diotallevi +7 more
doaj +1 more source
Revista da Sociedade Brasileira de Medicina Tropical, 2011 This is a case report of a Brazilian soldier with cutaneous leishmaniasis. The lesion relapsed following two systemic treatments with meglumine antimoniate.
Maria Inês Fernandes Pimentel +11 more
doaj +1 more source
Dermatology Research and Practice, 2011 The purpose of this study was to investigate comparison between oral zinc sulfate and meglumine antimoniate in the treatment of cutaneous leishmaniasis (CL). So 100 patients with CL were included and randomly divided into two groups.
Mohamad Javad Yazdanpanah +6 more
doaj +1 more source
FIRST REPORT ON OTOTOXICITY OF MEGLUMINE ANTIMONIATE
Revista do Instituto de Medicina Tropical de São Paulo, 2014 Introduction: Pentavalent antimonials are the first drug of choice in the treatment of tegumentary leishmaniasis. Data on ototoxicity related with such drugs is scarcely available in literature, leading us to develop a study on cochleovestibular ...
Cláudia Maria Valete-Rosalino +12 more
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Cost-effectiveness study of therapeutic approaches for mucosal leishmaniasis [PDF]
Cadernos de Saúde Pública: This study aimed to estimate the cost-effectiveness of four therapeutic approaches available for mucosal leishmaniasis in Brazil: miltefosine, meglumine antimoniate, combined with and without pentoxifylline, and liposomal amphotericin B.
Janaína de Pina Carvalho +5 more
doaj +1 more source