Results 171 to 180 of about 231,542 (282)

Phytochemical‐Based Strategies for Lung Cancer: Clinical Insights Into Pleiotropic Molecular Signaling and Therapeutic Roles

Phytotherapy Research, EarlyView.
Lung cancer (LC) remains the leading cause of global cancer‐related death. Phytochemicals from medicinal plants are increasingly being considered as potential LC treatment agents due to their multi‐targeted action, safety, and accessibility. These have anticancer properties by regulating key molecular signaling pathways.
Md. Rezaul Islam, Abdur Rauf, Happy Akter, Md. Ibrahim Khalil Al‐Imran, Md. Naeem Hossain Fakir, Gazi Kaifeara Thufa, Umme Habiba, Karjin Nahar Riya, Md. Mahfuzur Rahman, Md Sadique Hussain, Hanan A. Ogaly, Abdullah S. M. Aljohani, Waleed Al Abdulmonem, Dorota Formanowicz, Marcello Iriti   +14 more
wiley   +1 more source

MEK inhibition in adult patients with pilocytic astrocytomas. [PDF]

NPJ Precis Oncol
Rounis K, Delgado AF, Illies C, Shamikh A, Wangerid T, Jensdottir M, Bartek J, Persson O, Hietala MA, Friesland S, Carstens H, Stragliotto G.   +11 more
europepmc   +1 more source

Deep learning‐based ecological analysis of camera trap images is impacted by training data quality and quantity

Remote Sensing in Ecology and Conservation, EarlyView.
Machine learning image classifiers are increasingly being used to automate camera trap image labelling, but we don't know how much ML model accuracy matters for downstream ecological analyses. Using two large data sets from an African savannah and an Asian dry forest ecosystem, we compared human labelled data with predictions from deep‐learning models ...
Peggy A. Bevan, Omiros Pantazis, Holly A.I. Pringle, Guilherme Braga Ferreira, Daniel J. Ingram, Emily K. Madsen, Liam Thomas, Dol Raj Thanet, Thakur Silwal, Santosh Rayamajhi, Gabriel J. Brostow, Oisin Mac Aodha, Kate E. Jones   +12 more
wiley   +1 more source

Metabolic and behavioral effects of neurofibromin result from differential recruitment of MAPK and mTOR signaling. [PDF]

PLoS Genet
Botero V, Barrios J, Knauss A, Dahlen G, Rosendahl E, Colodner KJ, Tomchik SM.   +6 more
europepmc   +1 more source

Impact of Technological Innovation, Environmental Policy, and Policy Inclusion on Renewable Energy Adoption in Sub‐Sahara Africa

Thunderbird International Business Review, EarlyView.
ABSTRACT This study investigates the factors influencing renewable energy consumption and renewable electricity in Sub‐Sahara Africa (SSA) using the Lewbel 2SLS approach, panel quantile regression and Driscoll and Kraay estimator. It focuses on a panel dataset covering 41 countries from 1998 to 2020.
Emmanuel K. Manu, Simplice A. Asongu
wiley   +1 more source

Nintedanib Eye Drops Inhibit Alkali Burn-Induced Corneal Neovascularization Via RAP1/MEK/ERK Signaling Pathway. [PDF]

Invest Ophthalmol Vis Sci
Li J, Zhang G, Li J, Liu R, Zhu L, Li J, Li Z.   +6 more
europepmc   +1 more source

Global Attention and Mobility‐Enabled Knowledge: How Intermediate Units Gain Strategic Visibility in Multinational Corporations

Thunderbird International Business Review, EarlyView.
ABSTRACT This study examines how Intermediate Units (IUs) in multinational corporations gain the attention of corporate headquarters and subsidiaries. Using the Attention‐Based View, we show that attention depends on how visible and useful the IU's knowledge appears to other internal actors.
Jose Pla‐Barber, Ana Botella‐Andreu, Andrea Pallás‐Rocafull   +2 more
wiley   +1 more source

Ganglioside GM2 induces epithelial-mesenchymal transition (EMT) in cancer cells in a MEK/ERK/Egr1-dependent transcriptional program. [PDF]

J Biol Chem
Khamrui E, Banerjee S, Ray S, Ray A, Mahata B, Das T, Ghosh Z, Biswas K.   +7 more
europepmc   +1 more source

BRAF; MEK [PDF]

Science-Business eXchange, 2012
openaire   +1 more source

Do Financialization and Innovation Enhance Environmental Sustainability in Sub‐Saharan Africa?

Thunderbird International Business Review, EarlyView.
ABSTRACT This study addresses the perception of Sub‐Saharan Africa (SSA) as a region with limited financial capabilities and technological advancement to enhance environmental sustainability. Conducted across 24 SSA countries from 2000 to 2021, the research employs instrumental IV and panel quantile regressions.
Emmanuel Kwaku Manu, Maria L. Gorbunova, Simplice A. Asongu   +2 more
wiley   +1 more source