Results 21 to 30 of about 13,359 (150)

TCR Analyses of Two Vast and Shared Melanoma Antigen-Specific T Cell Repertoires: Common and Specific Features

open access: yesFrontiers in Immunology, 2018
Among Immunotherapeutic approaches for cancer treatment, the adoptive transfer of antigen specific T cells is still a relevant approach, that could have higher efficacy when further combined with immune check-point blockade.
Sylvain Simon   +21 more
doaj   +1 more source

Rhabdoid melanoma in a harpy eagle (Harpia harpyja)

open access: yesVeterinary and Animal Science, 2021
A 28-year-old male harpy eagle (Harpia harpyja) with a history of anorexia, hyporexia, lethargy, and progressive weight loss was found dead and submitted for post-mortem examination.
César Augusto Pinzón-Osorio   +3 more
doaj   +1 more source

A Study to Delineate the Immunohistological Parameters of Active Versus Stable Vitiligo Using S100, Melan A in Conjunction with CD4 and CD8 Immunohistochemistry Markers

open access: yesIndian Dermatology Online Journal
Background: Vitiligo is an autoimmune pigmentary disorder where it is important to assess the disease status (active/stable) to guide therapeutic decisions.
Sai Jyoti   +4 more
doaj   +1 more source

Bilateral adrenal cortical rests: An interesting innocuous intruder in the fallopian tubes

open access: yesIndian Journal of Pathology and Microbiology
Ectopic adrenal rests refer to the presence of adrenal tissue outside its normal anatomical location and are usually discovered incidentally on microscopic examination.
Nidha Gaffoor   +4 more
doaj   +1 more source

Fuzhuan Brick Tea Boosts Melanogenesis and Prevents Hair Graying through Reduction of Oxidative Stress via NRF2-HO-1 Signaling

open access: yesAntioxidants, 2022
The anti-graying effect of the hexane fraction of Fuzhuan brick tea is investigated in Melan-A cells and C57BL/6 mice. As a result, it is found that reactive oxygen species-induced damage is associated with the reduction of melanogenesis in hair bulb ...
Peijun Zhao   +3 more
doaj   +1 more source

Nuclear IDH3A Drives Transcriptional Programs in Melanoma via the YBX1–JUN/FOS Axis

open access: yesAdvanced Science, EarlyView.
Genomic amplification drives aberrant nuclear localization of IDH3A in melanoma. Independent of its canonical metabolic activity, nuclear IDH3A cooperates with YBX1 to activate the c‐JUN/c‐FOS transcriptional program, while NONO facilitates its nuclear localization.
Juan Ran   +10 more
wiley   +1 more source

Comparison of SOX-10, HMB-45, and Melan-A in Benign Melanocytic Lesions

open access: yesClinical, Cosmetic and Investigational Dermatology, 2021
Sabrina E Dass,1 Taryn Huizenga,2 Mehdi Farshchian,2 Darius R Mehregan2 1Wayne State University School of Medicine, Detroit, MI, USA; 2Department of Dermatology, Wayne State University, Detroit, MI, USACorrespondence: Mehdi FarshchianDepartment of ...
Dass SE   +3 more
doaj  

Challenges and Pitfalls to Diagnosing NUTM1‐Rearranged Neoplasia of the Pancreas by Cytology and Ancillary Studies

open access: yesDiagnostic Cytopathology, EarlyView.
ABSTRACT Fine‐needle aspiration cytology specimens are frequently utilized for ancillary studies to identify diagnostic and prognostic information. This case highlights diagnostic pitfalls and challenges in diagnosing NUTM1‐rearranged neoplasia on pancreatic cytology.
Terrance J. Lynn
wiley   +1 more source

Epithelioid Enigma: Proximal‐Type Epithelioid Sarcoma in Cyst Fluid Cytology

open access: yesDiagnostic Cytopathology, EarlyView.
ABSTRACT Epithelioid sarcoma (ES) is a rare, aggressive soft tissue malignancy with substantial morphologic overlap with other epithelioid neoplasms, creating diagnostic difficulty in cytology specimens. We report proximal‐type ES identified in cyst fluid from a lesion clinically interpreted as an epidermal inclusion cyst or abscess.
Nathan McGrath   +2 more
wiley   +1 more source

Cutis Verticis Gyrata Differential Diagnosis: Clinical Case

open access: yesВопросы современной педиатрии
Background. Cutis verticis gyrata is rare benign scalp disorder characterized by excessive skin and subcutaneous tissue proliferation and hypertrophy. Nowadays, there are three forms of this disease with various developmental mechanisms and associated ...
Tatiana S. Belysheva   +7 more
doaj   +1 more source

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