Results 131 to 140 of about 60,342 (231)
Abstract Glaucoma is a chronic optic neuropathy characterized by progressive vision loss. A previous study from our group showed that glaucoma‐induced retinal degeneration disrupts photic signaling to the suprachiasmatic nucleus (SCN), altering the molecular components of the central circadian clock.
Pietra Souza Barsanele +7 more
wiley +1 more source
ABSTRACT Background Hyperpigmentation, caused by excessive melanin accumulation, is a significant cosmetic concern in dermatology. Natural compounds are receiving attention as safe and effective skin‐lightening agents due to their antioxidant properties and ability to inhibit melanin synthesis.
Jung‐Wook Kang +4 more
wiley +1 more source
ABSTRACT Genome sharing in gonochorous species is expected to result in intraspecific conflicts due to intersexual competition. The emergence of sexual dimorphism is thus connected to the evolution of mechanisms that, starting from a similar genomic background, produce sufficiently disparate phenotypes to attenuate sexually antagonistic selection. From
Miguel Baltazar‐Soares +6 more
wiley +1 more source
Melanocortin-4 Receptor in Fish: A Review
The melanocortin-4 receptor (MC4R) belongs to the melanocortin system, has been well investigated in mammals. Which plays important roles in several physiological processes, such as regulating energy homeostasis, cachexia, cardiovascular function, glucose and lipid homeostasis, reproduction and sexual function, drug abuse, pain perception, brain ...
openaire +1 more source
Cold exposure and metabolic health: Therapeutic potential for obesity, diabetes, and beyond
Abstract Cold exposure, an inducer of brown adipose tissue thermogenesis, has been applied to relieve exercise‐induced pain and inflammation, modulate circulation and enhance metabolism. However, its role in managing metabolic diseases and the underlying molecular mechanisms remain inadequately understood.
Xirong Li +5 more
wiley +1 more source
Summary: Amphetamine (AMPH) exerts metabolic and cardiovascular effects. The central melanocortin system is a key regulator of both metabolic and cardiovascular functions.
Stephanie E. Simonds +12 more
doaj +1 more source
The central melanocortin system plays a critical role in the regulation of energy balance in rodents and humans. The melanocortin signals in both the hypothalamus and brainstem contribute to this regulation.
Fan, Wei +6 more
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