Results 131 to 140 of about 60,342 (231)

Retinal ganglion cell degeneration in glaucoma disrupts HPA axis temporal organization and dampens corticosterone production

open access: yesJournal of Neuroendocrinology, Volume 38, Issue 4, April 2026.
Abstract Glaucoma is a chronic optic neuropathy characterized by progressive vision loss. A previous study from our group showed that glaucoma‐induced retinal degeneration disrupts photic signaling to the suprachiasmatic nucleus (SCN), altering the molecular components of the central circadian clock.
Pietra Souza Barsanele   +7 more
wiley   +1 more source

Skin‐Lightening Efficacy of Leatherleaf Fern Extract and a Leatherleaf Fern‐Based Facial Serum In Vitro and Clinical Trial

open access: yesJournal of Cosmetic Dermatology, Volume 25, Issue 4, April 2026.
ABSTRACT Background Hyperpigmentation, caused by excessive melanin accumulation, is a significant cosmetic concern in dermatology. Natural compounds are receiving attention as safe and effective skin‐lightening agents due to their antioxidant properties and ability to inhibit melanin synthesis.
Jung‐Wook Kang   +4 more
wiley   +1 more source

Transcriptomics Reveal Molecular Signatures of a Resolved Sexual Conflict and Potential Association With Colour Polymorphism in Tawny Owls

open access: yesMolecular Ecology, Volume 35, Issue 7, April 2026.
ABSTRACT Genome sharing in gonochorous species is expected to result in intraspecific conflicts due to intersexual competition. The emergence of sexual dimorphism is thus connected to the evolution of mechanisms that, starting from a similar genomic background, produce sufficiently disparate phenotypes to attenuate sexually antagonistic selection. From
Miguel Baltazar‐Soares   +6 more
wiley   +1 more source

Melanocortin-4 Receptor in Fish: A Review

open access: yesInternational Journal of Agricultural Science and Food Technology, 2017
The melanocortin-4 receptor (MC4R) belongs to the melanocortin system, has been well investigated in mammals. Which plays important roles in several physiological processes, such as regulating energy homeostasis, cachexia, cardiovascular function, glucose and lipid homeostasis, reproduction and sexual function, drug abuse, pain perception, brain ...
openaire   +1 more source

Cold exposure and metabolic health: Therapeutic potential for obesity, diabetes, and beyond

open access: yesPhysiological Reports, Volume 14, Issue 7, April 2026.
Abstract Cold exposure, an inducer of brown adipose tissue thermogenesis, has been applied to relieve exercise‐induced pain and inflammation, modulate circulation and enhance metabolism. However, its role in managing metabolic diseases and the underlying molecular mechanisms remain inadequately understood.
Xirong Li   +5 more
wiley   +1 more source

Melanocortin 4 receptor (MC4R) [PDF]

open access: yesScience-Business eXchange, 2008
openaire   +1 more source

The metabolic and cardiovascular effects of amphetamine are partially mediated by the central melanocortin system

open access: yesCell Reports Medicine
Summary: Amphetamine (AMPH) exerts metabolic and cardiovascular effects. The central melanocortin system is a key regulator of both metabolic and cardiovascular functions.
Stephanie E. Simonds   +12 more
doaj   +1 more source

Melanocortin 4 receptor (MC4R) [PDF]

open access: yesScience-Business eXchange, 2009
openaire   +1 more source

Brainstem Raphe Pallidus and the Adjacent Area Contain a Novel Action Site in the Melanocortin Circuitry Regulating Energy Balance

open access: yes, 2008
The central melanocortin system plays a critical role in the regulation of energy balance in rodents and humans. The melanocortin signals in both the hypothalamus and brainstem contribute to this regulation.
Fan, Wei   +6 more
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