Results 121 to 130 of about 46,881 (189)

A thalamic circuit facilitates stress susceptibility via melanocortin 4 receptor-mediated activation of nucleus accumbens shell. [PDF]

CNS Neurosci Ther, 2023
Deng Q, Zhang SQ, Yang PF, Dong WT, Wang JL, Chen JG, Wang F, Long LH.   +7 more
europepmc   +1 more source

Orthopedia regulates melanocortin 4 receptor transcription and energy homeostasis. [PDF]

Sci Transl Med
Xu B, Lawler K, Wyler SC, Li L, Swati, Keogh JM, Chen X, Wan R, Almeida AG, Kirsch S, Mountjoy KG, Elmquist JK, Farooqi IS, Liu C.   +13 more
europepmc   +1 more source

Hyperphagia in rare melanocortin-4 receptor pathway diseases: therapeutic options and assessing treatment response. [PDF]

Rev Endocr Metab Disord
Argente J, Clément K, Duis J, Farooqi IS, Kühnen P, Miller JL, Roth CL, van den Akker E.   +7 more
europepmc   +1 more source

Melanocortin-4 receptor complexity in energy homeostasis,obesity and drug development strategies. [PDF]

Diabetes Obes Metab, 2022
Fatima MT, Ahmed I, Fakhro KA, Akil ASA.
europepmc   +1 more source

A peptide display system identifies a potent mutant β-melanocyte-stimulating hormone agonist of melanocortin-4 receptor. [PDF]

Cell Genom
Lin A, Spees K, Valbuena R, Wirbel J, Natarajan A, Enright N, Bhatt AS, Bassik MC.   +7 more
europepmc   +1 more source

Loss of melanocortin receptor accessory protein 2 in melanocortin-4 receptor neurons protect from obesity-associated autonomic and cardiovascular dysfunctions. [PDF]

Cardiovasc Res
Guo DF, Williams PA, Olson A, Morgan DA, Herz H, Resch J, Atasoy D, Stauss HM, Sebag JA, Rahmouni K.   +9 more
europepmc   +1 more source

N-Branched Tricyclic Guanidines as Novel Melanocortin-3 Receptor Agonists and Melanocortin-4 Receptor Antagonists. [PDF]

J Med Chem
Weirath NA, Zajac JWP, Donow HM, Lavoi TM, Pinilla C, Santos RG, Prajapati R, Speth R, Ericson MD, Sarupria S, Giulianotti MA, Haskell-Luevano C.   +11 more
europepmc   +1 more source

Melanocortin-4 Receptor Antagonism Inhibits Colorectal and Anaplastic Thyroid Cancer In Vitro and In Vivo. [PDF]

J Clin Med
Bandini A, Banchi M, Orlandi P, Vaglini F, Alì G, Fontanini G, Ottani A, Giuliani D, Vandini E, Francia G, Carli M, Scarselli M, Bocci G.   +12 more
europepmc   +1 more source

Melanocortin 4 receptor-expressing neurons in the lateral stripe of the striatum regulate affect and motor control. [PDF]

iScience
Sköld J, Lazzarino GP, Nett M, Wiskerke J, Engblom D.   +4 more
europepmc   +1 more source

High-resolution deep mutational scanning of the melanocortin-4 receptor enables target characterization for drug discovery. [PDF]

Elife
Howard CJ, Abell NS, Osuna BA, Jones EM, Chan LY, Chan H, Artis DR, Asfaha JB, Bloom JS, Cooper AR, Liao A, Mahdavi E, Mohammed N, Su AL, Uribe GA, Kosuri S, Dickel DE, Lubock NB.   +17 more
europepmc   +1 more source