Results 101 to 110 of about 46,881 (189)

Variasi Molekuler Gen Reseptor Melanokortin-4 pada Monyet Ekor Panjang

Jurnal Veteriner, 2010
Melanocortin-4 receptor (MC4R) is one of G protein-coupled receptors that plays an important role inregulation of energy homeostasis. MC4R mutations constitute the most common cause of human obesity.The study was conducted in order to investigate the ...
I Gusti Agung Arta Putra, Dondin Sajuthi, Dedy Duryadi Solihin, Raden Roro Dyah Perwitasari   +3 more
doaj  

Melanocortin 4 receptors and obesity [PDF]

Archives of Disease in Childhood, 2003
openaire   +1 more source

The role of accessory proteins and co-factors in regulation of melanocortin-4 receptor signalling: An update. [PDF]

J Neuroendocrinol
Jamaluddin A, McClellan A, Raffan E, Gorvin CM.   +3 more
europepmc   +1 more source

Mice lacking β-arrestin-2 in melanocortin 4 receptor–expressing neurons show marked metabolic deficits

JCI Insight
Hypothalamic melanocortin 4 receptors (MC4Rs) play a central role in regulating food intake and energy homeostasis. In fact, inactivating mutations in the MC4R gene are the most common form of monogenic obesity.
Misbah Rashid, Lei Wang, Zhenzhong Cui, Oksana Gavrilova, Huiyan Lu, Kozo Kaibuchi, Sarah Zeitlmayr, Thomas Gudermann, Andreas Breit, Jürgen Wess   +9 more
doaj   +1 more source

Molecular remodeling of the myocardium in mice with melanocortin-4 receptor deletion before cardiac function impairment. [PDF]

PLoS One
Wang X, Qi Y, Zhu Z, Wang C, Zhang Z, Jia H, Xia L, Meng K, Yuan J.   +8 more
europepmc   +1 more source

Melanocortin-4 receptor in macrophages attenuated angiotensin II-induced abdominal aortic aneurysm in mice. [PDF]

Sci Rep, 2023
Mori K, Okuma H, Nakamura S, Uchinuma H, Kaga S, Nakajima H, Ogawa Y, Tsuchiya K.   +7 more
europepmc   +1 more source

Improving the diagnosis of hyperphagia in melanocortin-4 receptor pathway diseases. [PDF]

Obesity (Silver Spring)
Abuzzahab MJ, Dubern B, Goldstone AP, Haqq AM, Heymsfield SB, Miller JL, Richards J, Wabitsch M, Yanovski JA.   +8 more
europepmc   +1 more source

Modulating food intake by nasal application of peptides targeting melanocortin 4 receptor and ghrelin receptor systems. [PDF]

Brain Commun
Özbay B, Jülke EM, List M, Nowicki M, Els-Heindl S, Immig K, Mörl K, Bechmann I, Beck-Sickinger AG.   +8 more
europepmc   +1 more source

Development of Melanocortin 4 Receptor Agonists by Exploiting Animal-Derived Macrocyclic, Disulfide-Rich Peptide Scaffolds. [PDF]

ACS Pharmacol Transl Sci, 2023
Muratspahić E, Aslanoglou D, White AM, Draxler C, Kozisek X, Farooq Z, Craik DJ, McCormick PJ, Durek T, Gruber CW.   +9 more
europepmc   +1 more source

The effect of melanocortin-4 receptor agonist drugs on obesity and metabolic risk factors: a systematic review and meta-analysis. [PDF]

Diabetol Metab Syndr
Sun Y, Abed M, Sohouli MH.
europepmc   +1 more source