Results 1 to 10 of about 78,152 (310)
BRG1 interacts with SOX10 to establish the melanocyte lineage and to promote differentiation [PDF]
Nucleic Acids Research, 2017 Mutations in SOX10 cause neurocristopathies which display varying degrees of hypopigmentation. Using a sensitized mutagenesis screen, we identified Smarca4 as a modifier gene that exacerbates the phenotypic severity of Sox10 haplo-insufficient mice ...
Dawn E Watkins-Chow +2 more
exaly +2 more sources
eLife, 2023 Tissue-resident stem and progenitor cells are present in many adult organs, where they are important for organ homeostasis and repair in response to injury. However, the signals that activate these cells and the mechanisms governing how these cells renew
William Tyler Frantz +5 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2023 Melanoma is the deadliest form of skin cancer and develops from the melanocytes that are responsible for the pigmentation of the skin. The skin is also a highly regenerative organ, harboring a pool of undifferentiated melanocyte stem cells that ...
Esra Katkat +10 more
doaj +1 more source
The neuropeptide alpha-melanocyte-stimulating hormone is critically involved in the development of cytotoxic CD8+ T cells in mice and humans. [PDF]
PLoS ONE, 2010 BACKGROUND: The neuropeptide alpha-melanocyte-stimulating hormone is well known as a mediator of skin pigmentation. More recently, it has been shown that alpha-melanocyte-stimulating hormone also plays pivotal roles in energy homeostasis, sexual function,
Karin Loser +10 more
doaj +1 more source
A Study of Normal Epidermal Melanocyte Distribution
International Journal of Dermatology and Venerology, 2021 . Objective:. To elucidate the epidermal melanocyte distribution according to sex, age, and body part with the goal of providing benchmark data for the diagnosis and therapeutic effect evaluation of pigmentary skin diseases. Methods:.
Kai-Lv Sun +4 more
doaj +1 more source
Mutations in gfpt1 and skiv2l2 cause distinct stage-specific defects in larval melanocyte regeneration in zebrafish. [PDF]
PLoS Genetics, 2007 The establishment of a single cell type regeneration paradigm in the zebrafish provides an opportunity to investigate the genetic mechanisms specific to regeneration processes.
Chao-Tsung Yang +3 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2023 Neural crest-derived cells play essential roles in skin function and homeostasis. However, how they interact with environmental cues and differentiate into functional skin cells remains unclear.
Shize Ma +13 more
doaj +1 more source
The First Live-Cell Based Product in The Iranian Drug List; ReColorCell® [PDF]
Cell Journal, 2023 Vitiligo is an autoimmune skin disorder that can significantly affect the quality of life in patients. However, currenttreatment strategies such as phototherapy, topical glucocorticosteroids, or systemic immunosuppressants canbe helpful in vitiligo ...
Mohammad Amin Shahrbaf +2 more
doaj +1 more source
Frontiers in Genetics, 2022 Egg production rate in chicken is related to the continuity of follicle development. In this study, we found that the numbers of white prehierarchical, dominant, and yellow preovulatory follicles in the high-yielding layer breed, White Leghorn (WL), were
Yurong Tai +8 more
doaj +1 more source
Mohs micrographic surgery for melanoma: A convincing treatment modality
Indian Journal of Dermatology, 2022 Mohs micrographic surgery (MMS) is the gold standard for treating keratinocyte carcinomas in specific locations or due to other tumor-specific factors, given its comprehensive margin assessment, tissue sparing, and high cure rate.
Stephanie Clements, Amor Khachemoune
doaj +1 more source